| Full name: zinc finger protein 146 | Alias Symbol: OZF | ||
| Type: protein-coding gene | Cytoband: 19q13.1 | ||
| Entrez ID: 7705 | HGNC ID: HGNC:12931 | Ensembl Gene: ENSG00000167635 | OMIM ID: 601505 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF146:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF146 | 7705 | 200050_at | 0.4211 | 0.2838 | |
| GSE20347 | ZNF146 | 7705 | 200050_at | 0.7414 | 0.0000 | |
| GSE23400 | ZNF146 | 7705 | 200050_at | 0.8501 | 0.0000 | |
| GSE26886 | ZNF146 | 7705 | 200050_at | 0.5445 | 0.0346 | |
| GSE29001 | ZNF146 | 7705 | 200050_at | 0.7263 | 0.0014 | |
| GSE38129 | ZNF146 | 7705 | 200050_at | 0.8674 | 0.0000 | |
| GSE45670 | ZNF146 | 7705 | 200050_at | 0.3436 | 0.0110 | |
| GSE53622 | ZNF146 | 7705 | 17736 | 0.6639 | 0.0000 | |
| GSE53624 | ZNF146 | 7705 | 17736 | 0.6741 | 0.0000 | |
| GSE63941 | ZNF146 | 7705 | 200050_at | 0.3211 | 0.5435 | |
| GSE77861 | ZNF146 | 7705 | 200050_at | 0.5940 | 0.0048 | |
| GSE97050 | ZNF146 | 7705 | A_23_P108028 | 0.5231 | 0.1539 | |
| SRP007169 | ZNF146 | 7705 | RNAseq | 2.2536 | 0.0003 | |
| SRP008496 | ZNF146 | 7705 | RNAseq | 1.9596 | 0.0000 | |
| SRP064894 | ZNF146 | 7705 | RNAseq | 0.5416 | 0.0259 | |
| SRP133303 | ZNF146 | 7705 | RNAseq | 0.7412 | 0.0013 | |
| SRP159526 | ZNF146 | 7705 | RNAseq | 0.8093 | 0.0102 | |
| SRP193095 | ZNF146 | 7705 | RNAseq | 0.3478 | 0.0004 | |
| SRP219564 | ZNF146 | 7705 | RNAseq | 0.1419 | 0.5435 | |
| TCGA | ZNF146 | 7705 | RNAseq | 0.1302 | 0.0100 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZNF146 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF146:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF146 | 7705 | 8 | 4 | 18 | |
| GSE20123 | ZNF146 | 7705 | 8 | 3 | 19 | |
| GSE43470 | ZNF146 | 7705 | 3 | 7 | 33 | |
| GSE46452 | ZNF146 | 7705 | 48 | 1 | 10 | |
| GSE47630 | ZNF146 | 7705 | 9 | 5 | 26 | |
| GSE54993 | ZNF146 | 7705 | 17 | 3 | 50 | |
| GSE54994 | ZNF146 | 7705 | 6 | 9 | 38 | |
| GSE60625 | ZNF146 | 7705 | 9 | 0 | 2 | |
| GSE74703 | ZNF146 | 7705 | 3 | 4 | 29 | |
| GSE74704 | ZNF146 | 7705 | 7 | 1 | 12 | |
| TCGA | ZNF146 | 7705 | 22 | 10 | 64 |
Total number of gains: 140; Total number of losses: 47; Total Number of normals: 301.
Somatic mutations of ZNF146:
Generating mutation plots.
Highly correlated genes for ZNF146:
Showing top 20/1788 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF146 | RBM26 | 0.910028 | 3 | 0 | 3 |
| ZNF146 | GLRX2 | 0.812533 | 3 | 0 | 3 |
| ZNF146 | EXOC8 | 0.797664 | 4 | 0 | 4 |
| ZNF146 | SLC25A29 | 0.767414 | 3 | 0 | 3 |
| ZNF146 | CELF1 | 0.762845 | 6 | 0 | 6 |
| ZNF146 | TMEM181 | 0.75722 | 4 | 0 | 4 |
| ZNF146 | WWP1 | 0.756287 | 3 | 0 | 3 |
| ZNF146 | SLC39A3 | 0.753735 | 3 | 0 | 3 |
| ZNF146 | ANAPC4 | 0.752906 | 3 | 0 | 3 |
| ZNF146 | IMMP1L | 0.752474 | 4 | 0 | 4 |
| ZNF146 | PLEKHH1 | 0.749741 | 3 | 0 | 3 |
| ZNF146 | ATP11C | 0.740371 | 4 | 0 | 3 |
| ZNF146 | KANSL3 | 0.739149 | 3 | 0 | 3 |
| ZNF146 | RNF217 | 0.734499 | 4 | 0 | 3 |
| ZNF146 | ZNF830 | 0.733942 | 3 | 0 | 3 |
| ZNF146 | UCK2 | 0.731205 | 3 | 0 | 3 |
| ZNF146 | NOL8 | 0.731178 | 6 | 0 | 5 |
| ZNF146 | MORC2 | 0.728905 | 11 | 0 | 11 |
| ZNF146 | UBA2 | 0.728826 | 13 | 0 | 11 |
| ZNF146 | RNASEH2B | 0.726885 | 5 | 0 | 4 |
For details and further investigation, click here
