| Full name: olfactory receptor family 2 subfamily T member 4 | Alias Symbol: OR2T4Q | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 127074 | HGNC ID: HGNC:15016 | Ensembl Gene: ENSG00000196944 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
OR2T4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR2T4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OR2T4 | 127074 | 123494 | 0.1448 | 0.0223 | |
| GSE53624 | OR2T4 | 127074 | 123494 | -0.0035 | 0.9749 | |
| GSE97050 | OR2T4 | 127074 | A_33_P3260680 | -0.0948 | 0.7123 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR2T4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR2T4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR2T4 | 127074 | 8 | 1 | 21 | |
| GSE20123 | OR2T4 | 127074 | 7 | 1 | 22 | |
| GSE43470 | OR2T4 | 127074 | 4 | 3 | 36 | |
| GSE46452 | OR2T4 | 127074 | 4 | 2 | 53 | |
| GSE47630 | OR2T4 | 127074 | 15 | 1 | 24 | |
| GSE54993 | OR2T4 | 127074 | 0 | 6 | 64 | |
| GSE54994 | OR2T4 | 127074 | 18 | 0 | 35 | |
| GSE60625 | OR2T4 | 127074 | 0 | 0 | 11 | |
| GSE74703 | OR2T4 | 127074 | 4 | 1 | 31 | |
| GSE74704 | OR2T4 | 127074 | 2 | 0 | 18 | |
| TCGA | OR2T4 | 127074 | 45 | 4 | 47 |
Total number of gains: 107; Total number of losses: 19; Total Number of normals: 362.
Somatic mutations of OR2T4:
Generating mutation plots.
Highly correlated genes for OR2T4:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR2T4 | OR2B11 | 0.833587 | 3 | 0 | 3 |
| OR2T4 | TTLL9 | 0.791925 | 3 | 0 | 3 |
| OR2T4 | EPHA10 | 0.780882 | 3 | 0 | 3 |
| OR2T4 | OR4D1 | 0.775728 | 3 | 0 | 3 |
| OR2T4 | TSSK3 | 0.770971 | 3 | 0 | 3 |
| OR2T4 | OR1F1 | 0.766617 | 3 | 0 | 3 |
| OR2T4 | OR2G2 | 0.757726 | 3 | 0 | 3 |
| OR2T4 | OR7G2 | 0.757517 | 3 | 0 | 3 |
| OR2T4 | ISLR2 | 0.749099 | 3 | 0 | 3 |
| OR2T4 | CIB3 | 0.748694 | 3 | 0 | 3 |
| OR2T4 | DDC | 0.740012 | 3 | 0 | 3 |
| OR2T4 | OR2A5 | 0.737181 | 3 | 0 | 3 |
| OR2T4 | AANAT | 0.729836 | 3 | 0 | 3 |
| OR2T4 | TEX13B | 0.728465 | 3 | 0 | 3 |
| OR2T4 | RBM43 | 0.727257 | 3 | 0 | 3 |
| OR2T4 | CPNE9 | 0.723026 | 3 | 0 | 3 |
| OR2T4 | SERPINA10 | 0.722931 | 3 | 0 | 3 |
| OR2T4 | FFAR1 | 0.722041 | 3 | 0 | 3 |
| OR2T4 | SLC22A12 | 0.719338 | 3 | 0 | 3 |
| OR2T4 | DEFB121 | 0.718544 | 3 | 0 | 3 |
For details and further investigation, click here
