| Full name: MAGE family member L2 | Alias Symbol: nM15 | ||
| Type: protein-coding gene | Cytoband: 15q11.2 | ||
| Entrez ID: 54551 | HGNC ID: HGNC:6814 | Ensembl Gene: ENSG00000254585 | OMIM ID: 605283 |
| Drug and gene relationship at DGIdb | |||
Expression of MAGEL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAGEL2 | 54551 | 219894_at | -0.1139 | 0.6241 | |
| GSE20347 | MAGEL2 | 54551 | 219894_at | 0.0523 | 0.4635 | |
| GSE23400 | MAGEL2 | 54551 | 219894_at | -0.1623 | 0.0000 | |
| GSE26886 | MAGEL2 | 54551 | 219894_at | 0.0467 | 0.8021 | |
| GSE29001 | MAGEL2 | 54551 | 219894_at | 0.0804 | 0.6318 | |
| GSE38129 | MAGEL2 | 54551 | 219894_at | 0.0812 | 0.3794 | |
| GSE45670 | MAGEL2 | 54551 | 219894_at | 0.0071 | 0.9517 | |
| GSE53622 | MAGEL2 | 54551 | 14834 | 0.3291 | 0.0000 | |
| GSE53624 | MAGEL2 | 54551 | 14834 | 0.2136 | 0.0113 | |
| GSE63941 | MAGEL2 | 54551 | 219894_at | -0.9936 | 0.0000 | |
| GSE77861 | MAGEL2 | 54551 | 219894_at | -0.2814 | 0.0495 | |
| GSE97050 | MAGEL2 | 54551 | A_23_P99996 | 0.0415 | 0.8707 | |
| TCGA | MAGEL2 | 54551 | RNAseq | -0.2040 | 0.6329 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAGEL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAGEL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAGEL2 | 54551 | 3 | 7 | 20 | |
| GSE20123 | MAGEL2 | 54551 | 2 | 7 | 21 | |
| GSE43470 | MAGEL2 | 54551 | 3 | 5 | 35 | |
| GSE46452 | MAGEL2 | 54551 | 3 | 7 | 49 | |
| GSE47630 | MAGEL2 | 54551 | 8 | 11 | 21 | |
| GSE54993 | MAGEL2 | 54551 | 4 | 6 | 60 | |
| GSE54994 | MAGEL2 | 54551 | 7 | 6 | 40 | |
| GSE60625 | MAGEL2 | 54551 | 4 | 3 | 4 | |
| GSE74703 | MAGEL2 | 54551 | 3 | 3 | 30 | |
| GSE74704 | MAGEL2 | 54551 | 1 | 5 | 14 | |
| TCGA | MAGEL2 | 54551 | 17 | 20 | 59 |
Total number of gains: 55; Total number of losses: 80; Total Number of normals: 353.
Somatic mutations of MAGEL2:
Generating mutation plots.
Highly correlated genes for MAGEL2:
Showing top 20/381 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAGEL2 | CNTN4 | 0.815998 | 3 | 0 | 3 |
| MAGEL2 | RGL4 | 0.775763 | 3 | 0 | 3 |
| MAGEL2 | TULP2 | 0.771313 | 3 | 0 | 3 |
| MAGEL2 | DRGX | 0.759463 | 3 | 0 | 3 |
| MAGEL2 | TCEAL7 | 0.747708 | 3 | 0 | 3 |
| MAGEL2 | CLEC12B | 0.737512 | 3 | 0 | 3 |
| MAGEL2 | RBM43 | 0.736278 | 4 | 0 | 4 |
| MAGEL2 | SPACA1 | 0.733005 | 4 | 0 | 3 |
| MAGEL2 | C9orf106 | 0.732587 | 3 | 0 | 3 |
| MAGEL2 | SETDB2 | 0.731413 | 3 | 0 | 3 |
| MAGEL2 | SPRED3 | 0.727478 | 3 | 0 | 3 |
| MAGEL2 | OR2D3 | 0.724529 | 3 | 0 | 3 |
| MAGEL2 | SPN | 0.719425 | 3 | 0 | 3 |
| MAGEL2 | ST8SIA1 | 0.719144 | 4 | 0 | 4 |
| MAGEL2 | PLB1 | 0.714621 | 3 | 0 | 3 |
| MAGEL2 | STK32C | 0.711982 | 3 | 0 | 3 |
| MAGEL2 | PRAMEF12 | 0.709802 | 3 | 0 | 3 |
| MAGEL2 | RXFP3 | 0.709799 | 3 | 0 | 3 |
| MAGEL2 | ZCCHC18 | 0.708937 | 5 | 0 | 5 |
| MAGEL2 | SHC3 | 0.704128 | 4 | 0 | 3 |
For details and further investigation, click here
