| Full name: poly(ADP-ribose) polymerase family member 6 | Alias Symbol: pART17 | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 56965 | HGNC ID: HGNC:26921 | Ensembl Gene: ENSG00000137817 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PARP6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARP6 | 56965 | 219639_x_at | -0.0032 | 0.9954 | |
| GSE20347 | PARP6 | 56965 | 219639_x_at | 0.5715 | 0.0313 | |
| GSE23400 | PARP6 | 56965 | 219639_x_at | -0.0758 | 0.1107 | |
| GSE26886 | PARP6 | 56965 | 219639_x_at | 0.4178 | 0.0198 | |
| GSE29001 | PARP6 | 56965 | 219639_x_at | 0.3282 | 0.1027 | |
| GSE38129 | PARP6 | 56965 | 219639_x_at | 0.3451 | 0.0373 | |
| GSE45670 | PARP6 | 56965 | 219639_x_at | 0.0312 | 0.8543 | |
| GSE53622 | PARP6 | 56965 | 64478 | 0.3599 | 0.0000 | |
| GSE53624 | PARP6 | 56965 | 64478 | 0.3306 | 0.0159 | |
| GSE63941 | PARP6 | 56965 | 219639_x_at | 0.1806 | 0.7727 | |
| GSE77861 | PARP6 | 56965 | 219639_x_at | -0.0792 | 0.6541 | |
| GSE97050 | PARP6 | 56965 | A_33_P3313302 | -0.0301 | 0.9326 | |
| SRP007169 | PARP6 | 56965 | RNAseq | 0.0249 | 0.9485 | |
| SRP008496 | PARP6 | 56965 | RNAseq | 0.4783 | 0.2691 | |
| SRP064894 | PARP6 | 56965 | RNAseq | 0.2855 | 0.0180 | |
| SRP133303 | PARP6 | 56965 | RNAseq | 0.3808 | 0.0215 | |
| SRP159526 | PARP6 | 56965 | RNAseq | 0.2578 | 0.2355 | |
| SRP193095 | PARP6 | 56965 | RNAseq | 0.5183 | 0.0000 | |
| SRP219564 | PARP6 | 56965 | RNAseq | 0.1529 | 0.6880 | |
| TCGA | PARP6 | 56965 | RNAseq | 0.0681 | 0.2961 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PARP6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARP6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARP6 | 56965 | 8 | 0 | 22 | |
| GSE20123 | PARP6 | 56965 | 8 | 0 | 22 | |
| GSE43470 | PARP6 | 56965 | 4 | 6 | 33 | |
| GSE46452 | PARP6 | 56965 | 3 | 7 | 49 | |
| GSE47630 | PARP6 | 56965 | 8 | 10 | 22 | |
| GSE54993 | PARP6 | 56965 | 5 | 6 | 59 | |
| GSE54994 | PARP6 | 56965 | 5 | 8 | 40 | |
| GSE60625 | PARP6 | 56965 | 4 | 4 | 3 | |
| GSE74703 | PARP6 | 56965 | 4 | 3 | 29 | |
| GSE74704 | PARP6 | 56965 | 4 | 0 | 16 | |
| TCGA | PARP6 | 56965 | 12 | 15 | 69 |
Total number of gains: 65; Total number of losses: 59; Total Number of normals: 364.
Somatic mutations of PARP6:
Generating mutation plots.
Highly correlated genes for PARP6:
Showing top 20/197 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARP6 | KRTAP12-2 | 0.896391 | 3 | 0 | 3 |
| PARP6 | LINC00454 | 0.791464 | 3 | 0 | 3 |
| PARP6 | KRTAP10-9 | 0.774691 | 3 | 0 | 3 |
| PARP6 | OR2T33 | 0.750153 | 3 | 0 | 3 |
| PARP6 | RFNG | 0.74729 | 3 | 0 | 3 |
| PARP6 | USP2-AS1 | 0.741934 | 3 | 0 | 3 |
| PARP6 | SYN3 | 0.735062 | 3 | 0 | 3 |
| PARP6 | SPEG | 0.733307 | 3 | 0 | 3 |
| PARP6 | ANKRD65 | 0.729882 | 3 | 0 | 3 |
| PARP6 | SLC26A5 | 0.729383 | 3 | 0 | 3 |
| PARP6 | KLHL33 | 0.729006 | 3 | 0 | 3 |
| PARP6 | BARHL1 | 0.724548 | 3 | 0 | 3 |
| PARP6 | C6orf163 | 0.720788 | 3 | 0 | 3 |
| PARP6 | ARL17A | 0.710248 | 3 | 0 | 3 |
| PARP6 | EID3 | 0.707871 | 3 | 0 | 3 |
| PARP6 | DNM3 | 0.706406 | 4 | 0 | 4 |
| PARP6 | GFAP | 0.698138 | 3 | 0 | 3 |
| PARP6 | GNPAT | 0.692356 | 3 | 0 | 3 |
| PARP6 | ADCY3 | 0.685886 | 3 | 0 | 3 |
| PARP6 | CCDC154 | 0.679901 | 4 | 0 | 3 |
For details and further investigation, click here
