| Full name: synapsin III | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 8224 | HGNC ID: HGNC:11496 | Ensembl Gene: ENSG00000185666 | OMIM ID: 602705 |
| Drug and gene relationship at DGIdb | |||
Expression of SYN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYN3 | 8224 | 206322_at | -0.0104 | 0.9798 | |
| GSE20347 | SYN3 | 8224 | 206322_at | -0.0144 | 0.8559 | |
| GSE23400 | SYN3 | 8224 | 206322_at | -0.0921 | 0.0051 | |
| GSE26886 | SYN3 | 8224 | 206322_at | 0.1582 | 0.1789 | |
| GSE29001 | SYN3 | 8224 | 206322_at | -0.0728 | 0.6140 | |
| GSE38129 | SYN3 | 8224 | 206322_at | 0.0227 | 0.7560 | |
| GSE45670 | SYN3 | 8224 | 206322_at | -0.0577 | 0.5448 | |
| GSE53622 | SYN3 | 8224 | 18176 | 0.0530 | 0.6017 | |
| GSE53624 | SYN3 | 8224 | 18176 | 0.2677 | 0.0429 | |
| GSE63941 | SYN3 | 8224 | 206322_at | 0.0208 | 0.9167 | |
| GSE77861 | SYN3 | 8224 | 206322_at | -0.1509 | 0.0705 | |
| GSE97050 | SYN3 | 8224 | A_33_P3279407 | -0.1137 | 0.5708 | |
| SRP007169 | SYN3 | 8224 | RNAseq | 0.8345 | 0.1939 | |
| SRP064894 | SYN3 | 8224 | RNAseq | 1.8563 | 0.0000 | |
| SRP133303 | SYN3 | 8224 | RNAseq | 0.5801 | 0.0213 | |
| SRP159526 | SYN3 | 8224 | RNAseq | 0.6630 | 0.1847 | |
| SRP193095 | SYN3 | 8224 | RNAseq | 0.0402 | 0.8652 | |
| SRP219564 | SYN3 | 8224 | RNAseq | 0.6296 | 0.4776 | |
| TCGA | SYN3 | 8224 | RNAseq | -0.1283 | 0.8503 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SYN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYN3 | 8224 | 4 | 5 | 21 | |
| GSE20123 | SYN3 | 8224 | 4 | 4 | 22 | |
| GSE43470 | SYN3 | 8224 | 5 | 5 | 33 | |
| GSE46452 | SYN3 | 8224 | 31 | 1 | 27 | |
| GSE47630 | SYN3 | 8224 | 8 | 5 | 27 | |
| GSE54993 | SYN3 | 8224 | 3 | 6 | 61 | |
| GSE54994 | SYN3 | 8224 | 9 | 10 | 34 | |
| GSE60625 | SYN3 | 8224 | 5 | 0 | 6 | |
| GSE74703 | SYN3 | 8224 | 4 | 5 | 27 | |
| GSE74704 | SYN3 | 8224 | 1 | 1 | 18 | |
| TCGA | SYN3 | 8224 | 28 | 15 | 53 |
Total number of gains: 102; Total number of losses: 57; Total Number of normals: 329.
Somatic mutations of SYN3:
Generating mutation plots.
Highly correlated genes for SYN3:
Showing top 20/367 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYN3 | CIDEB | 0.778645 | 3 | 0 | 3 |
| SYN3 | FIBCD1 | 0.740883 | 3 | 0 | 3 |
| SYN3 | ZBTB7A | 0.736471 | 4 | 0 | 3 |
| SYN3 | PDLIM2 | 0.736324 | 3 | 0 | 3 |
| SYN3 | PARP6 | 0.735062 | 3 | 0 | 3 |
| SYN3 | RPTOR | 0.732043 | 3 | 0 | 3 |
| SYN3 | F7 | 0.723581 | 3 | 0 | 3 |
| SYN3 | TMEM38A | 0.712844 | 3 | 0 | 3 |
| SYN3 | FBRS | 0.706958 | 3 | 0 | 3 |
| SYN3 | ZNF362 | 0.706334 | 3 | 0 | 3 |
| SYN3 | KDM5C | 0.705748 | 3 | 0 | 3 |
| SYN3 | FBXO31 | 0.704884 | 3 | 0 | 3 |
| SYN3 | ZNF324B | 0.702991 | 3 | 0 | 3 |
| SYN3 | APOB | 0.702519 | 5 | 0 | 4 |
| SYN3 | MINK1 | 0.700747 | 3 | 0 | 3 |
| SYN3 | ADAM15 | 0.700337 | 3 | 0 | 3 |
| SYN3 | F12 | 0.699092 | 3 | 0 | 3 |
| SYN3 | FKBP8 | 0.695507 | 4 | 0 | 3 |
| SYN3 | BCL9L | 0.69211 | 3 | 0 | 3 |
| SYN3 | C1orf159 | 0.691398 | 3 | 0 | 3 |
For details and further investigation, click here
