| Full name: RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 5986 | HGNC ID: HGNC:9974 | Ensembl Gene: ENSG00000169733 | OMIM ID: 602578 |
| Drug and gene relationship at DGIdb | |||
RFNG involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04330 | Notch signaling pathway |
Expression of RFNG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFNG | 5986 | 212968_at | 0.3798 | 0.4825 | |
| GSE20347 | RFNG | 5986 | 212968_at | -0.2070 | 0.0590 | |
| GSE23400 | RFNG | 5986 | 212968_at | -0.0201 | 0.7245 | |
| GSE26886 | RFNG | 5986 | 212968_at | 0.3936 | 0.0261 | |
| GSE29001 | RFNG | 5986 | 212968_at | -0.1223 | 0.4185 | |
| GSE38129 | RFNG | 5986 | 212968_at | -0.1841 | 0.0258 | |
| GSE45670 | RFNG | 5986 | 212968_at | -0.0375 | 0.7042 | |
| GSE53622 | RFNG | 5986 | 4437 | 0.0328 | 0.6473 | |
| GSE53624 | RFNG | 5986 | 4437 | 0.1318 | 0.0678 | |
| GSE63941 | RFNG | 5986 | 212968_at | -0.5202 | 0.1945 | |
| GSE77861 | RFNG | 5986 | 212968_at | -0.0774 | 0.7138 | |
| GSE97050 | RFNG | 5986 | A_23_P84629 | 0.3202 | 0.1657 | |
| SRP007169 | RFNG | 5986 | RNAseq | -0.5334 | 0.2013 | |
| SRP008496 | RFNG | 5986 | RNAseq | -0.7848 | 0.0129 | |
| SRP064894 | RFNG | 5986 | RNAseq | 0.6436 | 0.0375 | |
| SRP133303 | RFNG | 5986 | RNAseq | -0.2113 | 0.2348 | |
| SRP159526 | RFNG | 5986 | RNAseq | 0.2177 | 0.4363 | |
| SRP193095 | RFNG | 5986 | RNAseq | -0.2306 | 0.0208 | |
| SRP219564 | RFNG | 5986 | RNAseq | -0.1682 | 0.6473 | |
| TCGA | RFNG | 5986 | RNAseq | -0.0691 | 0.1832 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RFNG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFNG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFNG | 5986 | 4 | 4 | 22 | |
| GSE20123 | RFNG | 5986 | 4 | 4 | 22 | |
| GSE43470 | RFNG | 5986 | 3 | 5 | 35 | |
| GSE46452 | RFNG | 5986 | 34 | 0 | 25 | |
| GSE47630 | RFNG | 5986 | 9 | 2 | 29 | |
| GSE54993 | RFNG | 5986 | 2 | 5 | 63 | |
| GSE54994 | RFNG | 5986 | 10 | 6 | 37 | |
| GSE60625 | RFNG | 5986 | 6 | 0 | 5 | |
| GSE74703 | RFNG | 5986 | 3 | 3 | 30 | |
| GSE74704 | RFNG | 5986 | 4 | 3 | 13 | |
| TCGA | RFNG | 5986 | 24 | 13 | 59 |
Total number of gains: 103; Total number of losses: 45; Total Number of normals: 340.
Somatic mutations of RFNG:
Generating mutation plots.
Highly correlated genes for RFNG:
Showing top 20/303 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFNG | ANAPC5 | 0.864046 | 3 | 0 | 3 |
| RFNG | POP5 | 0.863274 | 3 | 0 | 3 |
| RFNG | THAP5 | 0.81879 | 3 | 0 | 3 |
| RFNG | ZFYVE27 | 0.816009 | 3 | 0 | 3 |
| RFNG | C1orf122 | 0.808085 | 3 | 0 | 3 |
| RFNG | MEA1 | 0.804173 | 3 | 0 | 3 |
| RFNG | ZNF764 | 0.798866 | 3 | 0 | 3 |
| RFNG | SMARCD1 | 0.790841 | 3 | 0 | 3 |
| RFNG | GYG2 | 0.789733 | 3 | 0 | 3 |
| RFNG | ANAPC11 | 0.78164 | 3 | 0 | 3 |
| RFNG | SPHK2 | 0.777579 | 3 | 0 | 3 |
| RFNG | NOL9 | 0.777312 | 3 | 0 | 3 |
| RFNG | CUTA | 0.773761 | 3 | 0 | 3 |
| RFNG | ELFN1 | 0.772536 | 3 | 0 | 3 |
| RFNG | FZD4 | 0.772443 | 3 | 0 | 3 |
| RFNG | EXOSC10 | 0.769909 | 3 | 0 | 3 |
| RFNG | SENP5 | 0.76725 | 3 | 0 | 3 |
| RFNG | MOB3C | 0.756822 | 3 | 0 | 3 |
| RFNG | INTS9 | 0.756511 | 3 | 0 | 3 |
| RFNG | GNL3 | 0.753746 | 3 | 0 | 3 |
For details and further investigation, click here
