| Full name: dynamin 3 | Alias Symbol: KIAA0820 | ||
| Type: protein-coding gene | Cytoband: 1q24.3 | ||
| Entrez ID: 26052 | HGNC ID: HGNC:29125 | Ensembl Gene: ENSG00000197959 | OMIM ID: 611445 |
| Drug and gene relationship at DGIdb | |||
DNM3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05100 | Bacterial invasion of epithelial cells |
Expression of DNM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNM3 | 26052 | 209839_at | 0.2587 | 0.4999 | |
| GSE20347 | DNM3 | 26052 | 209839_at | 0.3003 | 0.1301 | |
| GSE23400 | DNM3 | 26052 | 209839_at | -0.0166 | 0.7149 | |
| GSE26886 | DNM3 | 26052 | 1558502_s_at | -0.0121 | 0.9184 | |
| GSE29001 | DNM3 | 26052 | 209839_at | 0.5006 | 0.3609 | |
| GSE38129 | DNM3 | 26052 | 209839_at | -0.0013 | 0.9955 | |
| GSE45670 | DNM3 | 26052 | 209839_at | -0.0549 | 0.8941 | |
| GSE53622 | DNM3 | 26052 | 89252 | -0.5392 | 0.0001 | |
| GSE53624 | DNM3 | 26052 | 89252 | -0.1289 | 0.2433 | |
| GSE63941 | DNM3 | 26052 | 209839_at | -0.4106 | 0.5311 | |
| GSE77861 | DNM3 | 26052 | 1558502_s_at | -0.1068 | 0.5320 | |
| GSE97050 | DNM3 | 26052 | A_33_P3264364 | -0.5104 | 0.1664 | |
| SRP007169 | DNM3 | 26052 | RNAseq | 0.1096 | 0.8892 | |
| SRP064894 | DNM3 | 26052 | RNAseq | 0.4528 | 0.1099 | |
| SRP133303 | DNM3 | 26052 | RNAseq | -0.6224 | 0.0011 | |
| SRP159526 | DNM3 | 26052 | RNAseq | 0.3561 | 0.3575 | |
| SRP193095 | DNM3 | 26052 | RNAseq | 0.2159 | 0.3300 | |
| SRP219564 | DNM3 | 26052 | RNAseq | 0.4606 | 0.3462 | |
| TCGA | DNM3 | 26052 | RNAseq | -0.4058 | 0.0596 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNM3 | 26052 | 12 | 1 | 17 | |
| GSE20123 | DNM3 | 26052 | 12 | 1 | 17 | |
| GSE43470 | DNM3 | 26052 | 7 | 2 | 34 | |
| GSE46452 | DNM3 | 26052 | 3 | 1 | 55 | |
| GSE47630 | DNM3 | 26052 | 14 | 0 | 26 | |
| GSE54993 | DNM3 | 26052 | 0 | 6 | 64 | |
| GSE54994 | DNM3 | 26052 | 16 | 0 | 37 | |
| GSE60625 | DNM3 | 26052 | 0 | 0 | 11 | |
| GSE74703 | DNM3 | 26052 | 7 | 2 | 27 | |
| GSE74704 | DNM3 | 26052 | 6 | 0 | 14 | |
| TCGA | DNM3 | 26052 | 43 | 3 | 50 |
Total number of gains: 120; Total number of losses: 16; Total Number of normals: 352.
Somatic mutations of DNM3:
Generating mutation plots.
Highly correlated genes for DNM3:
Showing top 20/126 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNM3 | TEAD2 | 0.749884 | 3 | 0 | 3 |
| DNM3 | OBP2A | 0.711153 | 3 | 0 | 3 |
| DNM3 | PARD3B | 0.709199 | 3 | 0 | 3 |
| DNM3 | BCL7B | 0.709005 | 3 | 0 | 3 |
| DNM3 | PARP6 | 0.706406 | 4 | 0 | 4 |
| DNM3 | NCSTN | 0.68992 | 3 | 0 | 3 |
| DNM3 | TWISTNB | 0.682209 | 3 | 0 | 3 |
| DNM3 | GPR37L1 | 0.681078 | 3 | 0 | 3 |
| DNM3 | SH2B1 | 0.670781 | 3 | 0 | 3 |
| DNM3 | TRHDE | 0.667818 | 4 | 0 | 3 |
| DNM3 | SLC13A2 | 0.658878 | 3 | 0 | 3 |
| DNM3 | EXOC3L4 | 0.657738 | 3 | 0 | 3 |
| DNM3 | G0S2 | 0.655504 | 3 | 0 | 3 |
| DNM3 | AFP | 0.65547 | 3 | 0 | 3 |
| DNM3 | CLN6 | 0.653261 | 3 | 0 | 3 |
| DNM3 | BCORL1 | 0.650041 | 4 | 0 | 3 |
| DNM3 | RNF220 | 0.646069 | 3 | 0 | 3 |
| DNM3 | MSI1 | 0.645792 | 4 | 0 | 3 |
| DNM3 | TXNDC15 | 0.645069 | 4 | 0 | 4 |
| DNM3 | RAPGEF6 | 0.643766 | 4 | 0 | 3 |
For details and further investigation, click here
