| Full name: phytanoyl-CoA 2-hydroxylase interacting protein | Alias Symbol: KIAA0273|PAHX-AP | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 9796 | HGNC ID: HGNC:16865 | Ensembl Gene: ENSG00000168490 | OMIM ID: 608511 |
| Drug and gene relationship at DGIdb | |||
Expression of PHYHIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHYHIP | 9796 | 205325_at | -0.8171 | 0.0559 | |
| GSE20347 | PHYHIP | 9796 | 205325_at | -0.6575 | 0.0000 | |
| GSE23400 | PHYHIP | 9796 | 205325_at | -0.4210 | 0.0000 | |
| GSE26886 | PHYHIP | 9796 | 205325_at | -0.3866 | 0.0064 | |
| GSE29001 | PHYHIP | 9796 | 205325_at | -0.6124 | 0.0134 | |
| GSE38129 | PHYHIP | 9796 | 205325_at | -0.7821 | 0.0000 | |
| GSE45670 | PHYHIP | 9796 | 205325_at | -0.3292 | 0.0087 | |
| GSE53622 | PHYHIP | 9796 | 14518 | -0.7270 | 0.0000 | |
| GSE53624 | PHYHIP | 9796 | 14518 | -0.7946 | 0.0000 | |
| GSE63941 | PHYHIP | 9796 | 205325_at | 0.1317 | 0.4942 | |
| GSE77861 | PHYHIP | 9796 | 205325_at | -0.6062 | 0.0048 | |
| GSE97050 | PHYHIP | 9796 | A_23_P433229 | -0.2236 | 0.5183 | |
| SRP064894 | PHYHIP | 9796 | RNAseq | -2.1078 | 0.0000 | |
| SRP133303 | PHYHIP | 9796 | RNAseq | -3.3302 | 0.0000 | |
| SRP159526 | PHYHIP | 9796 | RNAseq | -1.8027 | 0.0376 | |
| SRP219564 | PHYHIP | 9796 | RNAseq | -0.7035 | 0.4158 | |
| TCGA | PHYHIP | 9796 | RNAseq | -0.9898 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by PHYHIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHYHIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHYHIP | 9796 | 4 | 10 | 16 | |
| GSE20123 | PHYHIP | 9796 | 4 | 10 | 16 | |
| GSE43470 | PHYHIP | 9796 | 4 | 9 | 30 | |
| GSE46452 | PHYHIP | 9796 | 13 | 13 | 33 | |
| GSE47630 | PHYHIP | 9796 | 10 | 8 | 22 | |
| GSE54993 | PHYHIP | 9796 | 2 | 14 | 54 | |
| GSE54994 | PHYHIP | 9796 | 9 | 17 | 27 | |
| GSE60625 | PHYHIP | 9796 | 3 | 0 | 8 | |
| GSE74703 | PHYHIP | 9796 | 4 | 7 | 25 | |
| GSE74704 | PHYHIP | 9796 | 3 | 7 | 10 | |
| TCGA | PHYHIP | 9796 | 14 | 43 | 39 |
Total number of gains: 70; Total number of losses: 138; Total Number of normals: 280.
Somatic mutations of PHYHIP:
Generating mutation plots.
Highly correlated genes for PHYHIP:
Showing top 20/839 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHYHIP | SMDT1 | 0.780403 | 3 | 0 | 3 |
| PHYHIP | IGSF22 | 0.775076 | 3 | 0 | 3 |
| PHYHIP | THRSP | 0.76925 | 3 | 0 | 3 |
| PHYHIP | KIF6 | 0.75198 | 3 | 0 | 3 |
| PHYHIP | C9orf106 | 0.751339 | 3 | 0 | 3 |
| PHYHIP | GPR146 | 0.749119 | 3 | 0 | 3 |
| PHYHIP | OR51T1 | 0.748184 | 3 | 0 | 3 |
| PHYHIP | TPRX1 | 0.747224 | 3 | 0 | 3 |
| PHYHIP | MFSD2B | 0.744981 | 4 | 0 | 4 |
| PHYHIP | SNORA68 | 0.744887 | 4 | 0 | 4 |
| PHYHIP | FAM95B1 | 0.742834 | 4 | 0 | 4 |
| PHYHIP | OR2Z1 | 0.741747 | 3 | 0 | 3 |
| PHYHIP | KRTAP20-1 | 0.741664 | 3 | 0 | 3 |
| PHYHIP | SUMF1 | 0.738458 | 3 | 0 | 3 |
| PHYHIP | ANKDD1A | 0.734283 | 3 | 0 | 3 |
| PHYHIP | OR13G1 | 0.731706 | 3 | 0 | 3 |
| PHYHIP | OR10G3 | 0.729717 | 3 | 0 | 3 |
| PHYHIP | CATSPER3 | 0.727731 | 4 | 0 | 3 |
| PHYHIP | KBTBD13 | 0.727521 | 3 | 0 | 3 |
| PHYHIP | ZDHHC20 | 0.724974 | 3 | 0 | 3 |
For details and further investigation, click here
