| Full name: zinc finger DHHC-type containing 20 | Alias Symbol: FLJ25952|DHHC20 | ||
| Type: protein-coding gene | Cytoband: 13q12.11 | ||
| Entrez ID: 253832 | HGNC ID: HGNC:20749 | Ensembl Gene: ENSG00000180776 | OMIM ID: 617972 |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC20 | 253832 | 225365_at | -0.1472 | 0.8216 | |
| GSE26886 | ZDHHC20 | 253832 | 225365_at | -0.7372 | 0.0008 | |
| GSE45670 | ZDHHC20 | 253832 | 225365_at | -0.3628 | 0.0217 | |
| GSE53622 | ZDHHC20 | 253832 | 19601 | 0.2856 | 0.0000 | |
| GSE53624 | ZDHHC20 | 253832 | 19601 | 0.2455 | 0.0001 | |
| GSE63941 | ZDHHC20 | 253832 | 225365_at | 0.1816 | 0.5995 | |
| GSE77861 | ZDHHC20 | 253832 | 225365_at | -0.8880 | 0.0016 | |
| GSE97050 | ZDHHC20 | 253832 | A_33_P3221177 | -0.0909 | 0.6790 | |
| SRP007169 | ZDHHC20 | 253832 | RNAseq | -2.3172 | 0.0000 | |
| SRP008496 | ZDHHC20 | 253832 | RNAseq | -2.0518 | 0.0000 | |
| SRP064894 | ZDHHC20 | 253832 | RNAseq | -0.8611 | 0.0002 | |
| SRP133303 | ZDHHC20 | 253832 | RNAseq | -0.4750 | 0.0157 | |
| SRP159526 | ZDHHC20 | 253832 | RNAseq | -1.0967 | 0.0000 | |
| SRP193095 | ZDHHC20 | 253832 | RNAseq | -1.3332 | 0.0000 | |
| SRP219564 | ZDHHC20 | 253832 | RNAseq | -1.4194 | 0.0024 | |
| TCGA | ZDHHC20 | 253832 | RNAseq | -0.1093 | 0.1609 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ZDHHC20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC20 | 253832 | 1 | 14 | 15 | |
| GSE20123 | ZDHHC20 | 253832 | 1 | 13 | 16 | |
| GSE43470 | ZDHHC20 | 253832 | 2 | 13 | 28 | |
| GSE46452 | ZDHHC20 | 253832 | 0 | 33 | 26 | |
| GSE47630 | ZDHHC20 | 253832 | 3 | 26 | 11 | |
| GSE54993 | ZDHHC20 | 253832 | 11 | 2 | 57 | |
| GSE54994 | ZDHHC20 | 253832 | 1 | 13 | 39 | |
| GSE60625 | ZDHHC20 | 253832 | 0 | 3 | 8 | |
| GSE74703 | ZDHHC20 | 253832 | 2 | 10 | 24 | |
| GSE74704 | ZDHHC20 | 253832 | 0 | 11 | 9 | |
| TCGA | ZDHHC20 | 253832 | 6 | 43 | 47 |
Total number of gains: 27; Total number of losses: 181; Total Number of normals: 280.
Somatic mutations of ZDHHC20:
Generating mutation plots.
Highly correlated genes for ZDHHC20:
Showing top 20/281 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC20 | KANK3 | 0.86178 | 3 | 0 | 3 |
| ZDHHC20 | CXorf38 | 0.841714 | 4 | 0 | 4 |
| ZDHHC20 | ZDHHC13 | 0.763028 | 4 | 0 | 4 |
| ZDHHC20 | KLF17 | 0.754013 | 4 | 0 | 4 |
| ZDHHC20 | LARP4B | 0.75388 | 3 | 0 | 3 |
| ZDHHC20 | EBP | 0.751903 | 3 | 0 | 3 |
| ZDHHC20 | C15orf40 | 0.750731 | 4 | 0 | 4 |
| ZDHHC20 | CRTAC1 | 0.749596 | 3 | 0 | 3 |
| ZDHHC20 | EPB41L4A | 0.746931 | 4 | 0 | 4 |
| ZDHHC20 | MFSD1 | 0.746866 | 5 | 0 | 5 |
| ZDHHC20 | IKZF2 | 0.739159 | 4 | 0 | 4 |
| ZDHHC20 | ZNF780A | 0.7386 | 3 | 0 | 3 |
| ZDHHC20 | MFSD11 | 0.73781 | 3 | 0 | 3 |
| ZDHHC20 | MAP3K9 | 0.734933 | 4 | 0 | 4 |
| ZDHHC20 | TMEM125 | 0.734749 | 4 | 0 | 4 |
| ZDHHC20 | PLAGL1 | 0.731552 | 3 | 0 | 3 |
| ZDHHC20 | NIPAL2 | 0.730239 | 4 | 0 | 4 |
| ZDHHC20 | CPNE3 | 0.727894 | 4 | 0 | 4 |
| ZDHHC20 | CDS1 | 0.727697 | 4 | 0 | 4 |
| ZDHHC20 | PHYHIP | 0.724974 | 3 | 0 | 3 |
For details and further investigation, click here
