| Full name: tetrapeptide repeat homeobox 1 | Alias Symbol: FLJ40321 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 284355 | HGNC ID: HGNC:32174 | Ensembl Gene: ENSG00000178928 | OMIM ID: 611166 |
| Drug and gene relationship at DGIdb | |||
Expression of TPRX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TPRX1 | 284355 | 13416 | -0.6672 | 0.0000 | |
| GSE53624 | TPRX1 | 284355 | 13416 | -0.2284 | 0.0090 | |
| GSE97050 | TPRX1 | 284355 | A_24_P323997 | -0.2656 | 0.2615 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TPRX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TPRX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPRX1 | 284355 | 4 | 4 | 22 | |
| GSE20123 | TPRX1 | 284355 | 4 | 3 | 23 | |
| GSE43470 | TPRX1 | 284355 | 3 | 10 | 30 | |
| GSE46452 | TPRX1 | 284355 | 45 | 1 | 13 | |
| GSE47630 | TPRX1 | 284355 | 8 | 7 | 25 | |
| GSE54993 | TPRX1 | 284355 | 17 | 4 | 49 | |
| GSE54994 | TPRX1 | 284355 | 4 | 14 | 35 | |
| GSE60625 | TPRX1 | 284355 | 9 | 0 | 2 | |
| GSE74703 | TPRX1 | 284355 | 3 | 7 | 26 | |
| GSE74704 | TPRX1 | 284355 | 4 | 1 | 15 | |
| TCGA | TPRX1 | 284355 | 15 | 18 | 63 |
Total number of gains: 116; Total number of losses: 69; Total Number of normals: 303.
Somatic mutations of TPRX1:
Generating mutation plots.
Highly correlated genes for TPRX1:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPRX1 | PRG3 | 0.826267 | 3 | 0 | 3 |
| TPRX1 | KRTAP6-1 | 0.802557 | 3 | 0 | 3 |
| TPRX1 | PKD2L1 | 0.800557 | 3 | 0 | 3 |
| TPRX1 | MFSD2B | 0.792845 | 3 | 0 | 3 |
| TPRX1 | OR51T1 | 0.788028 | 3 | 0 | 3 |
| TPRX1 | CHRND | 0.785304 | 3 | 0 | 3 |
| TPRX1 | MAP3K10 | 0.7792 | 3 | 0 | 3 |
| TPRX1 | GDF7 | 0.774387 | 3 | 0 | 3 |
| TPRX1 | FXYD2 | 0.773837 | 3 | 0 | 3 |
| TPRX1 | HTR3A | 0.773136 | 3 | 0 | 3 |
| TPRX1 | OR2Z1 | 0.770162 | 3 | 0 | 3 |
| TPRX1 | TFAP2E | 0.769005 | 3 | 0 | 3 |
| TPRX1 | RRP1 | 0.768891 | 3 | 0 | 3 |
| TPRX1 | OR10G3 | 0.763426 | 3 | 0 | 3 |
| TPRX1 | ZNF235 | 0.760203 | 3 | 0 | 3 |
| TPRX1 | OR13G1 | 0.759023 | 3 | 0 | 3 |
| TPRX1 | NT5C1A | 0.758707 | 3 | 0 | 3 |
| TPRX1 | KRTAP20-1 | 0.755593 | 3 | 0 | 3 |
| TPRX1 | PAX2 | 0.752052 | 3 | 0 | 3 |
| TPRX1 | PSPN | 0.75193 | 3 | 0 | 3 |
For details and further investigation, click here
