| Full name: immunoglobulin superfamily member 22 | Alias Symbol: FLJ37794|IGFN2 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 283284 | HGNC ID: HGNC:26750 | Ensembl Gene: ENSG00000179057 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IGSF22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGSF22 | 283284 | 1553857_at | -0.3158 | 0.1564 | |
| GSE26886 | IGSF22 | 283284 | 1553857_at | -0.2136 | 0.0604 | |
| GSE45670 | IGSF22 | 283284 | 1553857_at | -0.0468 | 0.6836 | |
| GSE63941 | IGSF22 | 283284 | 1553857_at | 0.1220 | 0.5581 | |
| GSE77861 | IGSF22 | 283284 | 1553857_at | 0.0148 | 0.9283 | |
| GSE97050 | IGSF22 | 283284 | A_32_P486620 | 0.0511 | 0.8190 | |
| SRP133303 | IGSF22 | 283284 | RNAseq | -0.9019 | 0.0039 | |
| SRP219564 | IGSF22 | 283284 | RNAseq | -0.7804 | 0.1502 | |
| TCGA | IGSF22 | 283284 | RNAseq | -0.9275 | 0.0680 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IGSF22 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of IGSF22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGSF22 | 283284 | 0 | 10 | 20 | |
| GSE20123 | IGSF22 | 283284 | 0 | 10 | 20 | |
| GSE43470 | IGSF22 | 283284 | 1 | 5 | 37 | |
| GSE46452 | IGSF22 | 283284 | 7 | 5 | 47 | |
| GSE47630 | IGSF22 | 283284 | 3 | 10 | 27 | |
| GSE54993 | IGSF22 | 283284 | 3 | 0 | 67 | |
| GSE54994 | IGSF22 | 283284 | 3 | 12 | 38 | |
| GSE60625 | IGSF22 | 283284 | 0 | 0 | 11 | |
| GSE74703 | IGSF22 | 283284 | 1 | 3 | 32 | |
| GSE74704 | IGSF22 | 283284 | 0 | 9 | 11 | |
| TCGA | IGSF22 | 283284 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 93; Total Number of normals: 366.
Somatic mutations of IGSF22:
Generating mutation plots.
Highly correlated genes for IGSF22:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGSF22 | PHYHIP | 0.775076 | 3 | 0 | 3 |
| IGSF22 | RNF215 | 0.715961 | 3 | 0 | 3 |
| IGSF22 | LY6H | 0.713261 | 3 | 0 | 3 |
| IGSF22 | OR3A3 | 0.698322 | 3 | 0 | 3 |
| IGSF22 | PDZRN3 | 0.697448 | 3 | 0 | 3 |
| IGSF22 | ZNF763 | 0.67151 | 3 | 0 | 3 |
| IGSF22 | HAP1 | 0.669366 | 3 | 0 | 3 |
| IGSF22 | F2RL3 | 0.667873 | 3 | 0 | 3 |
| IGSF22 | CD200R1 | 0.666624 | 3 | 0 | 3 |
| IGSF22 | IL17B | 0.663805 | 3 | 0 | 3 |
| IGSF22 | SLC22A7 | 0.663683 | 3 | 0 | 3 |
| IGSF22 | CCDC61 | 0.659551 | 4 | 0 | 3 |
| IGSF22 | CLYBL-AS2 | 0.658077 | 3 | 0 | 3 |
| IGSF22 | KLKB1 | 0.653244 | 3 | 0 | 3 |
| IGSF22 | GAB2 | 0.650262 | 3 | 0 | 3 |
| IGSF22 | IL37 | 0.648328 | 3 | 0 | 3 |
| IGSF22 | RAX2 | 0.645728 | 4 | 0 | 4 |
| IGSF22 | CA4 | 0.640383 | 3 | 0 | 3 |
| IGSF22 | NTF3 | 0.639632 | 3 | 0 | 3 |
| IGSF22 | NRXN1 | 0.6321 | 4 | 0 | 3 |
For details and further investigation, click here
