| Full name: kinesin family member 6 | Alias Symbol: dJ1043E3.1|MGC33317|dJ137F1.4|dJ188D3.1|DKFZp451I2418 | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 221458 | HGNC ID: HGNC:21202 | Ensembl Gene: ENSG00000164627 | OMIM ID: 613919 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF6 | 221458 | 1556232_at | 0.0399 | 0.9084 | |
| GSE26886 | KIF6 | 221458 | 1556232_at | 0.0437 | 0.7184 | |
| GSE45670 | KIF6 | 221458 | 1556232_at | 0.0137 | 0.9053 | |
| GSE53622 | KIF6 | 221458 | 410 | -0.0210 | 0.8787 | |
| GSE53624 | KIF6 | 221458 | 410 | 0.2184 | 0.0163 | |
| GSE63941 | KIF6 | 221458 | 1556232_at | 0.0169 | 0.9467 | |
| GSE77861 | KIF6 | 221458 | 1552538_a_at | -0.2764 | 0.0284 | |
| GSE97050 | KIF6 | 221458 | A_33_P3330643 | 0.0629 | 0.7542 | |
| SRP007169 | KIF6 | 221458 | RNAseq | 0.9068 | 0.2752 | |
| SRP064894 | KIF6 | 221458 | RNAseq | -0.0611 | 0.7653 | |
| SRP133303 | KIF6 | 221458 | RNAseq | -0.0516 | 0.6648 | |
| SRP159526 | KIF6 | 221458 | RNAseq | 1.0245 | 0.0108 | |
| SRP193095 | KIF6 | 221458 | RNAseq | 0.0687 | 0.6474 | |
| SRP219564 | KIF6 | 221458 | RNAseq | 0.1099 | 0.8276 | |
| TCGA | KIF6 | 221458 | RNAseq | -0.6933 | 0.0627 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KIF6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF6 | 221458 | 4 | 1 | 25 | |
| GSE20123 | KIF6 | 221458 | 4 | 1 | 25 | |
| GSE43470 | KIF6 | 221458 | 6 | 0 | 37 | |
| GSE46452 | KIF6 | 221458 | 2 | 9 | 48 | |
| GSE47630 | KIF6 | 221458 | 8 | 4 | 28 | |
| GSE54993 | KIF6 | 221458 | 3 | 2 | 65 | |
| GSE54994 | KIF6 | 221458 | 11 | 4 | 38 | |
| GSE60625 | KIF6 | 221458 | 0 | 1 | 10 | |
| GSE74703 | KIF6 | 221458 | 6 | 0 | 30 | |
| GSE74704 | KIF6 | 221458 | 1 | 1 | 18 | |
| TCGA | KIF6 | 221458 | 17 | 14 | 65 |
Total number of gains: 62; Total number of losses: 37; Total Number of normals: 389.
Somatic mutations of KIF6:
Generating mutation plots.
Highly correlated genes for KIF6:
Showing top 20/98 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF6 | C16orf82 | 0.801823 | 3 | 0 | 3 |
| KIF6 | ZNF568 | 0.758594 | 3 | 0 | 3 |
| KIF6 | PHYHIP | 0.75198 | 3 | 0 | 3 |
| KIF6 | TTC39A | 0.737291 | 3 | 0 | 3 |
| KIF6 | C20orf173 | 0.733915 | 3 | 0 | 3 |
| KIF6 | FAM71A | 0.728909 | 4 | 0 | 3 |
| KIF6 | EPS8L2 | 0.718216 | 3 | 0 | 3 |
| KIF6 | PALM3 | 0.717037 | 4 | 0 | 4 |
| KIF6 | GRID2 | 0.716306 | 3 | 0 | 3 |
| KIF6 | CA4 | 0.715888 | 3 | 0 | 3 |
| KIF6 | C4BPA | 0.714303 | 4 | 0 | 4 |
| KIF6 | TREH | 0.704298 | 3 | 0 | 3 |
| KIF6 | OR2H2 | 0.70052 | 3 | 0 | 3 |
| KIF6 | C10orf71 | 0.696986 | 3 | 0 | 3 |
| KIF6 | GPR78 | 0.69386 | 3 | 0 | 3 |
| KIF6 | SHD | 0.681006 | 3 | 0 | 3 |
| KIF6 | SORCS3 | 0.680848 | 3 | 0 | 3 |
| KIF6 | ITIH3 | 0.674395 | 4 | 0 | 3 |
| KIF6 | NTRK1 | 0.66434 | 3 | 0 | 3 |
| KIF6 | CATSPER3 | 0.658742 | 4 | 0 | 3 |
For details and further investigation, click here
