| Full name: thyroid hormone responsive | Alias Symbol: SPOT14|Lpgp|S14|THRP | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 7069 | HGNC ID: HGNC:11800 | Ensembl Gene: ENSG00000151365 | OMIM ID: 601926 |
| Drug and gene relationship at DGIdb | |||
Expression of THRSP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THRSP | 7069 | 1553583_a_at | -0.1312 | 0.4794 | |
| GSE26886 | THRSP | 7069 | 1553583_a_at | -0.0111 | 0.9393 | |
| GSE45670 | THRSP | 7069 | 1553583_a_at | -0.0305 | 0.7911 | |
| GSE53622 | THRSP | 7069 | 62081 | 0.0484 | 0.5471 | |
| GSE53624 | THRSP | 7069 | 62081 | 0.0479 | 0.5607 | |
| GSE63941 | THRSP | 7069 | 229477_at | 0.0204 | 0.9375 | |
| GSE77861 | THRSP | 7069 | 1553583_a_at | -0.1363 | 0.1641 | |
| GSE97050 | THRSP | 7069 | A_23_P363954 | 0.1185 | 0.5808 | |
| TCGA | THRSP | 7069 | RNAseq | -1.5101 | 0.0474 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by THRSP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THRSP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THRSP | 7069 | 3 | 10 | 17 | |
| GSE20123 | THRSP | 7069 | 3 | 9 | 18 | |
| GSE43470 | THRSP | 7069 | 3 | 5 | 35 | |
| GSE46452 | THRSP | 7069 | 7 | 22 | 30 | |
| GSE47630 | THRSP | 7069 | 4 | 17 | 19 | |
| GSE54993 | THRSP | 7069 | 8 | 2 | 60 | |
| GSE54994 | THRSP | 7069 | 5 | 17 | 31 | |
| GSE60625 | THRSP | 7069 | 4 | 3 | 4 | |
| GSE74703 | THRSP | 7069 | 2 | 4 | 30 | |
| GSE74704 | THRSP | 7069 | 3 | 5 | 12 | |
| TCGA | THRSP | 7069 | 18 | 32 | 46 |
Total number of gains: 60; Total number of losses: 126; Total Number of normals: 302.
Somatic mutations of THRSP:
Generating mutation plots.
Highly correlated genes for THRSP:
Showing top 20/283 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THRSP | HMGCLL1 | 0.827603 | 3 | 0 | 3 |
| THRSP | PHYHIP | 0.76925 | 3 | 0 | 3 |
| THRSP | CRTAC1 | 0.748654 | 3 | 0 | 3 |
| THRSP | ADORA1 | 0.737581 | 3 | 0 | 3 |
| THRSP | PPM1N | 0.733316 | 3 | 0 | 3 |
| THRSP | TSPAN32 | 0.720841 | 3 | 0 | 3 |
| THRSP | SLC25A47 | 0.71928 | 4 | 0 | 4 |
| THRSP | MYH13 | 0.71402 | 4 | 0 | 4 |
| THRSP | HAAO | 0.712249 | 4 | 0 | 4 |
| THRSP | NXF3 | 0.711796 | 3 | 0 | 3 |
| THRSP | TERT | 0.70342 | 3 | 0 | 3 |
| THRSP | RASL10B | 0.700533 | 4 | 0 | 3 |
| THRSP | DPEP3 | 0.695373 | 4 | 0 | 3 |
| THRSP | LMAN1L | 0.695278 | 4 | 0 | 4 |
| THRSP | KCNT1 | 0.684928 | 4 | 0 | 4 |
| THRSP | ZMYND10 | 0.683997 | 5 | 0 | 4 |
| THRSP | NRXN1 | 0.683514 | 3 | 0 | 3 |
| THRSP | IL17B | 0.682003 | 3 | 0 | 3 |
| THRSP | TEF | 0.681159 | 3 | 0 | 3 |
| THRSP | S100A1 | 0.681059 | 3 | 0 | 3 |
For details and further investigation, click here
