POLR3E

 

Full name: RNA polymerase III subunit E Alias Symbol: RPC5|SIN|FLJ10509
Type: protein-coding gene Cytoband: 16p12.2
Entrez ID: 55718 HGNC ID: HGNC:30347 Ensembl Gene: ENSG00000058600 OMIM ID: 617815
Screen Evidence:

 

Expression of POLR3E:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 POLR3E 55718 233459_at 0.0532 0.8100
GSE26886 POLR3E 55718 233459_at -0.1565 0.2623
GSE45670 POLR3E 55718 233459_at 0.0857 0.4261
GSE53622 POLR3E 55718 22775 0.1715 0.0021
GSE53624 POLR3E 55718 22775 0.2868 0.0000
GSE63941 POLR3E 55718 233459_at 0.0739 0.6940
GSE77861 POLR3E 55718 233459_at 0.0076 0.9312
GSE97050 POLR3E 55718 A_23_P152181 0.0669 0.8594
SRP007169 POLR3E 55718 RNAseq 0.2820 0.4366
SRP008496 POLR3E 55718 RNAseq 0.3946 0.1535
SRP064894 POLR3E 55718 RNAseq -0.2041 0.1968
SRP133303 POLR3E 55718 RNAseq 0.1660 0.3606
SRP159526 POLR3E 55718 RNAseq 0.2911 0.1082
SRP193095 POLR3E 55718 RNAseq 0.2071 0.0151
SRP219564 POLR3E 55718 RNAseq -0.0101 0.9716
TCGA POLR3E 55718 RNAseq -0.0492 0.3255

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by POLR3E expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of POLR3E:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 POLR3E 55718 6 3 21
GSE20123 POLR3E 55718 6 2 22
GSE43470 POLR3E 55718 3 3 37
GSE46452 POLR3E 55718 38 1 20
GSE47630 POLR3E 55718 11 6 23
GSE54993 POLR3E 55718 3 5 62
GSE54994 POLR3E 55718 3 10 40
GSE60625 POLR3E 55718 4 0 7
GSE74703 POLR3E 55718 3 2 31
GSE74704 POLR3E 55718 3 1 16
TCGA POLR3E 55718 19 13 64

Total number of gains: 99; Total number of losses: 46; Total Number of normals: 343.  


 

Somatic mutations of POLR3E:

 

Generating mutation plots.

 

Highly correlated genes for POLR3E:

 

Showing all 18 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
POLR3ELYPD80.667048303
POLR3ETEX280.640244404
POLR3EZNF5980.605936404
POLR3EC14orf1780.578843303
POLR3EACTR50.568687303
POLR3ETMPRSS50.568083404
POLR3EKDM4D0.560224404
POLR3EZNF4290.557045504
POLR3EPPIB0.554859303
POLR3ESLC22A18AS0.553589403
POLR3EC16orf910.547886403
POLR3EZBTB20-AS10.514961403
POLR3ETHOC60.510397503
POLR3EGPR37L10.509176403
POLR3ERNPS10.50819503
POLR3EEARS20.507369603
POLR3EHCCAT50.503176504
POLR3EDNAJA30.502346503

For details and further investigation, click here