| Full name: zinc finger protein 598 | Alias Symbol: FLJ00086|HEL2 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 90850 | HGNC ID: HGNC:28079 | Ensembl Gene: ENSG00000167962 | OMIM ID: 617508 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF598:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF598 | 90850 | 225104_at | 0.7306 | 0.1116 | |
| GSE26886 | ZNF598 | 90850 | 232367_x_at | -0.2761 | 0.2005 | |
| GSE45670 | ZNF598 | 90850 | 225104_at | 0.8167 | 0.0000 | |
| GSE53622 | ZNF598 | 90850 | 147548 | 0.7292 | 0.0000 | |
| GSE53624 | ZNF598 | 90850 | 147548 | 0.6910 | 0.0000 | |
| GSE63941 | ZNF598 | 90850 | 225104_at | 0.3790 | 0.2249 | |
| GSE77861 | ZNF598 | 90850 | 232367_x_at | 0.0126 | 0.9528 | |
| GSE97050 | ZNF598 | 90850 | A_23_P407684 | 0.7626 | 0.1113 | |
| SRP007169 | ZNF598 | 90850 | RNAseq | 0.0328 | 0.9396 | |
| SRP008496 | ZNF598 | 90850 | RNAseq | 0.0509 | 0.8521 | |
| SRP064894 | ZNF598 | 90850 | RNAseq | 0.3703 | 0.0823 | |
| SRP133303 | ZNF598 | 90850 | RNAseq | 0.7408 | 0.0000 | |
| SRP159526 | ZNF598 | 90850 | RNAseq | 0.3814 | 0.2276 | |
| SRP193095 | ZNF598 | 90850 | RNAseq | 0.7977 | 0.0000 | |
| SRP219564 | ZNF598 | 90850 | RNAseq | 0.7213 | 0.1568 | |
| TCGA | ZNF598 | 90850 | RNAseq | 0.1802 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF598 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF598:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF598 | 90850 | 5 | 5 | 20 | |
| GSE20123 | ZNF598 | 90850 | 5 | 4 | 21 | |
| GSE43470 | ZNF598 | 90850 | 4 | 7 | 32 | |
| GSE46452 | ZNF598 | 90850 | 38 | 1 | 20 | |
| GSE47630 | ZNF598 | 90850 | 13 | 6 | 21 | |
| GSE54993 | ZNF598 | 90850 | 3 | 5 | 62 | |
| GSE54994 | ZNF598 | 90850 | 5 | 9 | 39 | |
| GSE60625 | ZNF598 | 90850 | 4 | 0 | 7 | |
| GSE74703 | ZNF598 | 90850 | 4 | 5 | 27 | |
| GSE74704 | ZNF598 | 90850 | 3 | 2 | 15 | |
| TCGA | ZNF598 | 90850 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of ZNF598:
Generating mutation plots.
Highly correlated genes for ZNF598:
Showing top 20/561 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF598 | PGP | 0.765698 | 3 | 0 | 3 |
| ZNF598 | PSMC3IP | 0.751752 | 3 | 0 | 3 |
| ZNF598 | NTMT1 | 0.751252 | 3 | 0 | 3 |
| ZNF598 | CD276 | 0.750222 | 3 | 0 | 3 |
| ZNF598 | DNAJA3 | 0.74321 | 4 | 0 | 4 |
| ZNF598 | CDCA3 | 0.738447 | 3 | 0 | 3 |
| ZNF598 | PHLDA3 | 0.737667 | 3 | 0 | 3 |
| ZNF598 | ACOT7 | 0.734146 | 4 | 0 | 4 |
| ZNF598 | POC1A | 0.726821 | 3 | 0 | 3 |
| ZNF598 | CDC6 | 0.723925 | 3 | 0 | 3 |
| ZNF598 | TXNDC12 | 0.722607 | 4 | 0 | 4 |
| ZNF598 | RUVBL1 | 0.716347 | 4 | 0 | 4 |
| ZNF598 | ORC1 | 0.716105 | 3 | 0 | 3 |
| ZNF598 | THOC6 | 0.713746 | 3 | 0 | 3 |
| ZNF598 | APCS | 0.710532 | 4 | 0 | 4 |
| ZNF598 | GPBAR1 | 0.710477 | 3 | 0 | 3 |
| ZNF598 | DCTPP1 | 0.709484 | 4 | 0 | 4 |
| ZNF598 | OGFOD2 | 0.704054 | 4 | 0 | 4 |
| ZNF598 | CDCA8 | 0.703357 | 5 | 0 | 4 |
| ZNF598 | C19orf48 | 0.70301 | 3 | 0 | 3 |
For details and further investigation, click here
