| Full name: RNA binding protein with serine rich domain 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 10921 | HGNC ID: HGNC:10080 | Ensembl Gene: ENSG00000205937 | OMIM ID: 606447 |
| Drug and gene relationship at DGIdb | |||
Expression of RNPS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNPS1 | 10921 | 200060_s_at | 0.6287 | 0.0953 | |
| GSE20347 | RNPS1 | 10921 | 200060_s_at | 0.8471 | 0.0000 | |
| GSE23400 | RNPS1 | 10921 | 200060_s_at | 0.6366 | 0.0000 | |
| GSE26886 | RNPS1 | 10921 | 200060_s_at | 0.0861 | 0.6275 | |
| GSE29001 | RNPS1 | 10921 | 200060_s_at | 0.6149 | 0.0307 | |
| GSE38129 | RNPS1 | 10921 | 200060_s_at | 0.7390 | 0.0000 | |
| GSE45670 | RNPS1 | 10921 | 200060_s_at | 0.3963 | 0.0055 | |
| GSE53622 | RNPS1 | 10921 | 4296 | 0.6809 | 0.0000 | |
| GSE53624 | RNPS1 | 10921 | 37546 | 0.8449 | 0.0000 | |
| GSE63941 | RNPS1 | 10921 | 200060_s_at | 1.3881 | 0.0000 | |
| GSE77861 | RNPS1 | 10921 | 200060_s_at | 0.7218 | 0.0009 | |
| GSE97050 | RNPS1 | 10921 | A_23_P152272 | 0.4856 | 0.1783 | |
| SRP007169 | RNPS1 | 10921 | RNAseq | 0.7403 | 0.0213 | |
| SRP008496 | RNPS1 | 10921 | RNAseq | 0.7923 | 0.0000 | |
| SRP064894 | RNPS1 | 10921 | RNAseq | 0.4821 | 0.0038 | |
| SRP133303 | RNPS1 | 10921 | RNAseq | 0.7863 | 0.0000 | |
| SRP159526 | RNPS1 | 10921 | RNAseq | 0.5622 | 0.0138 | |
| SRP193095 | RNPS1 | 10921 | RNAseq | 0.5860 | 0.0000 | |
| SRP219564 | RNPS1 | 10921 | RNAseq | 0.5398 | 0.0958 | |
| TCGA | RNPS1 | 10921 | RNAseq | 0.2052 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RNPS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNPS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNPS1 | 10921 | 5 | 5 | 20 | |
| GSE20123 | RNPS1 | 10921 | 5 | 4 | 21 | |
| GSE43470 | RNPS1 | 10921 | 4 | 7 | 32 | |
| GSE46452 | RNPS1 | 10921 | 38 | 1 | 20 | |
| GSE47630 | RNPS1 | 10921 | 13 | 6 | 21 | |
| GSE54993 | RNPS1 | 10921 | 3 | 5 | 62 | |
| GSE54994 | RNPS1 | 10921 | 5 | 9 | 39 | |
| GSE60625 | RNPS1 | 10921 | 4 | 0 | 7 | |
| GSE74703 | RNPS1 | 10921 | 4 | 5 | 27 | |
| GSE74704 | RNPS1 | 10921 | 3 | 2 | 15 | |
| TCGA | RNPS1 | 10921 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of RNPS1:
Generating mutation plots.
Highly correlated genes for RNPS1:
Showing top 20/1906 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNPS1 | CCDC117 | 0.797331 | 3 | 0 | 3 |
| RNPS1 | KLF13 | 0.791686 | 4 | 0 | 4 |
| RNPS1 | ALKBH6 | 0.788985 | 3 | 0 | 3 |
| RNPS1 | MCM6 | 0.787309 | 10 | 0 | 10 |
| RNPS1 | FKTN | 0.780484 | 3 | 0 | 3 |
| RNPS1 | MCM7 | 0.777979 | 10 | 0 | 9 |
| RNPS1 | LRRC58 | 0.777065 | 4 | 0 | 4 |
| RNPS1 | MSH6 | 0.774287 | 10 | 0 | 10 |
| RNPS1 | USP42 | 0.773903 | 6 | 0 | 6 |
| RNPS1 | SPNS1 | 0.773052 | 5 | 0 | 5 |
| RNPS1 | FARS2 | 0.770953 | 3 | 0 | 3 |
| RNPS1 | PFDN2 | 0.767388 | 9 | 0 | 9 |
| RNPS1 | RFC4 | 0.767362 | 10 | 0 | 9 |
| RNPS1 | SENP1 | 0.76387 | 3 | 0 | 3 |
| RNPS1 | RILPL2 | 0.758892 | 3 | 0 | 3 |
| RNPS1 | ILF3 | 0.753305 | 11 | 0 | 10 |
| RNPS1 | FBXO16 | 0.749272 | 3 | 0 | 3 |
| RNPS1 | ZNF707 | 0.748784 | 3 | 0 | 3 |
| RNPS1 | EBNA1BP2 | 0.748181 | 3 | 0 | 3 |
| RNPS1 | ELAVL1 | 0.748073 | 7 | 0 | 7 |
For details and further investigation, click here
