| Full name: actin related protein 5 | Alias Symbol: FLJ12785|Arp5|INO80M | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 79913 | HGNC ID: HGNC:14671 | Ensembl Gene: ENSG00000101442 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ACTR5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTR5 | 79913 | 219623_at | 0.6518 | 0.2418 | |
| GSE20347 | ACTR5 | 79913 | 219623_at | 0.3181 | 0.0132 | |
| GSE23400 | ACTR5 | 79913 | 219623_at | 0.2406 | 0.0000 | |
| GSE26886 | ACTR5 | 79913 | 219623_at | 0.4077 | 0.0067 | |
| GSE29001 | ACTR5 | 79913 | 219623_at | 0.6337 | 0.0241 | |
| GSE38129 | ACTR5 | 79913 | 219623_at | 0.3228 | 0.0050 | |
| GSE45670 | ACTR5 | 79913 | 219623_at | 0.1812 | 0.1981 | |
| GSE53622 | ACTR5 | 79913 | 167586 | 0.5580 | 0.0000 | |
| GSE53624 | ACTR5 | 79913 | 167586 | 0.4458 | 0.0000 | |
| GSE63941 | ACTR5 | 79913 | 219623_at | 0.3061 | 0.3468 | |
| GSE77861 | ACTR5 | 79913 | 219623_at | -0.0924 | 0.5237 | |
| GSE97050 | ACTR5 | 79913 | A_23_P165952 | 0.4093 | 0.1839 | |
| SRP007169 | ACTR5 | 79913 | RNAseq | 0.8444 | 0.0871 | |
| SRP008496 | ACTR5 | 79913 | RNAseq | 0.5961 | 0.0759 | |
| SRP064894 | ACTR5 | 79913 | RNAseq | 0.7968 | 0.0001 | |
| SRP133303 | ACTR5 | 79913 | RNAseq | 0.4240 | 0.0061 | |
| SRP159526 | ACTR5 | 79913 | RNAseq | 0.2142 | 0.4439 | |
| SRP193095 | ACTR5 | 79913 | RNAseq | 0.1539 | 0.1599 | |
| SRP219564 | ACTR5 | 79913 | RNAseq | 0.5238 | 0.1778 | |
| TCGA | ACTR5 | 79913 | RNAseq | 0.1818 | 0.0080 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACTR5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTR5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTR5 | 79913 | 14 | 2 | 14 | |
| GSE20123 | ACTR5 | 79913 | 14 | 2 | 14 | |
| GSE43470 | ACTR5 | 79913 | 13 | 0 | 30 | |
| GSE46452 | ACTR5 | 79913 | 29 | 0 | 30 | |
| GSE47630 | ACTR5 | 79913 | 24 | 0 | 16 | |
| GSE54993 | ACTR5 | 79913 | 0 | 17 | 53 | |
| GSE54994 | ACTR5 | 79913 | 24 | 0 | 29 | |
| GSE60625 | ACTR5 | 79913 | 0 | 0 | 11 | |
| GSE74703 | ACTR5 | 79913 | 10 | 0 | 26 | |
| GSE74704 | ACTR5 | 79913 | 10 | 1 | 9 | |
| TCGA | ACTR5 | 79913 | 47 | 4 | 45 |
Total number of gains: 185; Total number of losses: 26; Total Number of normals: 277.
Somatic mutations of ACTR5:
Generating mutation plots.
Highly correlated genes for ACTR5:
Showing top 20/258 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTR5 | ULBP3 | 0.752027 | 3 | 0 | 3 |
| ACTR5 | STK4-AS1 | 0.693928 | 4 | 0 | 4 |
| ACTR5 | PASD1 | 0.693806 | 3 | 0 | 3 |
| ACTR5 | MMP15 | 0.687 | 3 | 0 | 3 |
| ACTR5 | CDK5RAP1 | 0.682864 | 11 | 0 | 11 |
| ACTR5 | DDX27 | 0.673473 | 10 | 0 | 10 |
| ACTR5 | PDRG1 | 0.649352 | 5 | 0 | 4 |
| ACTR5 | CKAP2L | 0.639553 | 4 | 0 | 4 |
| ACTR5 | CSE1L | 0.638351 | 10 | 0 | 10 |
| ACTR5 | DNAJC14 | 0.63693 | 3 | 0 | 3 |
| ACTR5 | BLCAP | 0.632947 | 10 | 0 | 10 |
| ACTR5 | NFS1 | 0.627389 | 10 | 0 | 9 |
| ACTR5 | RIOK1 | 0.623088 | 4 | 0 | 4 |
| ACTR5 | RALGAPB | 0.621913 | 6 | 0 | 5 |
| ACTR5 | CCM2 | 0.616001 | 3 | 0 | 3 |
| ACTR5 | CSTF1 | 0.615847 | 11 | 0 | 8 |
| ACTR5 | PTPN1 | 0.615182 | 6 | 0 | 5 |
| ACTR5 | RAE1 | 0.614034 | 11 | 0 | 8 |
| ACTR5 | NOP14 | 0.612711 | 4 | 0 | 3 |
| ACTR5 | TOP1 | 0.612004 | 9 | 0 | 7 |
For details and further investigation, click here
