KDM4D

 

Full name: lysine demethylase 4D Alias Symbol: FLJ10251
Type: protein-coding gene Cytoband: 11q21
Entrez ID: 55693 HGNC ID: HGNC:25498 Ensembl Gene: ENSG00000186280 OMIM ID: 609766

 

Expression of KDM4D:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KDM4D 55693 242788_at 0.1742 0.3766
GSE20347 KDM4D 55693 220278_at 0.1696 0.0507
GSE23400 KDM4D 55693 220278_at 0.0385 0.1004
GSE26886 KDM4D 55693 242788_at 0.0712 0.5073
GSE29001 KDM4D 55693 220278_at 0.2773 0.0297
GSE38129 KDM4D 55693 220278_at 0.1135 0.1450
GSE45670 KDM4D 55693 242788_at 0.1128 0.3228
GSE53622 KDM4D 55693 803 0.6360 0.0000
GSE53624 KDM4D 55693 803 0.9641 0.0000
GSE63941 KDM4D 55693 242788_at 0.2301 0.2436
GSE77861 KDM4D 55693 242788_at -0.0451 0.7427
GSE97050 KDM4D 55693 A_23_P127406 -0.0587 0.8772
SRP007169 KDM4D 55693 RNAseq 1.4110 0.0540
SRP133303 KDM4D 55693 RNAseq 0.0152 0.9603
SRP159526 KDM4D 55693 RNAseq 1.0973 0.0224
SRP219564 KDM4D 55693 RNAseq 0.3915 0.4278
TCGA KDM4D 55693 RNAseq 0.5712 0.0002

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by KDM4D expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of KDM4D:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KDM4D 55693 3 8 19
GSE20123 KDM4D 55693 3 8 19
GSE43470 KDM4D 55693 2 5 36
GSE46452 KDM4D 55693 5 24 30
GSE47630 KDM4D 55693 2 19 19
GSE54993 KDM4D 55693 8 2 60
GSE54994 KDM4D 55693 7 18 28
GSE60625 KDM4D 55693 0 3 8
GSE74703 KDM4D 55693 1 4 31
GSE74704 KDM4D 55693 3 4 13
TCGA KDM4D 55693 11 43 42

Total number of gains: 45; Total number of losses: 138; Total Number of normals: 305.  


 

Somatic mutations of KDM4D:

 

Generating mutation plots.

 

Highly correlated genes for KDM4D:

 

Showing top 20/381 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KDM4DSAAL10.65811404
KDM4DCLSPN0.657996403
KDM4DORAI10.656662303
KDM4DPRDX30.650805404
KDM4DMRPS230.646896404
KDM4DCKAP2L0.644038403
KDM4DBOLA30.634458403
KDM4DSLC35B20.633373303
KDM4DZBTB410.631006303
KDM4DKLHL120.628581404
KDM4DSLC25A170.62545605
KDM4DHEATR60.619536504
KDM4DDDIAS0.615906303
KDM4DVRK10.615905504
KDM4DDDX200.613112403
KDM4DPANK40.612893303
KDM4DACACA0.611539303
KDM4DABCF10.611303303
KDM4DZNF280C0.610097303
KDM4DHEATR10.607704505

For details and further investigation, click here