RGS8

 

Full name: regulator of G protein signaling 8 Alias Symbol: MGC119067|MGC119068|MGC119069
Type: protein-coding gene Cytoband: 1q25.3
Entrez ID: 85397 HGNC ID: HGNC:16810 Ensembl Gene: ENSG00000135824 OMIM ID: 607189
Drug and gene relationship at DGIdb

 

Expression of RGS8:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RGS8 85397 224390_s_at -0.0132 0.9672
GSE26886 RGS8 85397 224390_s_at 0.1777 0.1040
GSE45670 RGS8 85397 224390_s_at -0.0312 0.8029
GSE53622 RGS8 85397 6097 0.2958 0.0068
GSE53624 RGS8 85397 6097 0.4660 0.0000
GSE63941 RGS8 85397 224390_s_at 0.0224 0.8967
GSE77861 RGS8 85397 224390_s_at -0.1031 0.3635

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by RGS8 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RGS8:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RGS8 85397 12 0 18
GSE20123 RGS8 85397 12 0 18
GSE43470 RGS8 85397 7 1 35
GSE46452 RGS8 85397 3 1 55
GSE47630 RGS8 85397 14 0 26
GSE54993 RGS8 85397 0 6 64
GSE54994 RGS8 85397 15 0 38
GSE60625 RGS8 85397 0 0 11
GSE74703 RGS8 85397 7 1 28
GSE74704 RGS8 85397 5 0 15
TCGA RGS8 85397 40 3 53

Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.  

 

Somatic mutations of RGS8:

 

Generating mutation plots.

 

Highly correlated genes for RGS8:

 

Showing all 12 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RGS8GAP430.664823303
RGS8LINC008410.634383303
RGS8RPL34-AS10.627341303
RGS8NEURL20.614083303
RGS8OR13C40.560824403
RGS8RASSF40.559508303
RGS8TBATA0.557093404
RGS8TNFAIP8L20.556698303
RGS8SMAD1-AS20.535982403
RGS8SNX320.532293303
RGS8JAK30.5267403
RGS8GJD40.519597403

For details and further investigation, click here