| Full name: neuralized E3 ubiquitin protein ligase 2 | Alias Symbol: dJ337O18.6|FLJ30259|Ozz|Ozz-E3 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 140825 | HGNC ID: HGNC:16156 | Ensembl Gene: ENSG00000124257 | OMIM ID: 608597 |
| Drug and gene relationship at DGIdb | |||
Expression of NEURL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEURL2 | 140825 | 230283_at | -0.1086 | 0.7847 | |
| GSE26886 | NEURL2 | 140825 | 230283_at | 0.4904 | 0.0021 | |
| GSE45670 | NEURL2 | 140825 | 230283_at | -0.0568 | 0.5430 | |
| GSE53622 | NEURL2 | 140825 | 767 | -0.0369 | 0.7238 | |
| GSE53624 | NEURL2 | 140825 | 767 | 0.0982 | 0.2731 | |
| GSE63941 | NEURL2 | 140825 | 230283_at | -0.1202 | 0.7052 | |
| GSE77861 | NEURL2 | 140825 | 230283_at | -0.0221 | 0.8235 | |
| GSE97050 | NEURL2 | 140825 | A_23_P165989 | -0.0759 | 0.8080 | |
| SRP133303 | NEURL2 | 140825 | RNAseq | -0.2136 | 0.4991 | |
| SRP219564 | NEURL2 | 140825 | RNAseq | 0.2569 | 0.7340 | |
| TCGA | NEURL2 | 140825 | RNAseq | -0.3213 | 0.0257 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NEURL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEURL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEURL2 | 140825 | 14 | 1 | 15 | |
| GSE20123 | NEURL2 | 140825 | 14 | 1 | 15 | |
| GSE43470 | NEURL2 | 140825 | 12 | 1 | 30 | |
| GSE46452 | NEURL2 | 140825 | 29 | 0 | 30 | |
| GSE47630 | NEURL2 | 140825 | 24 | 1 | 15 | |
| GSE54993 | NEURL2 | 140825 | 0 | 17 | 53 | |
| GSE54994 | NEURL2 | 140825 | 25 | 0 | 28 | |
| GSE60625 | NEURL2 | 140825 | 0 | 0 | 11 | |
| GSE74703 | NEURL2 | 140825 | 10 | 1 | 25 | |
| GSE74704 | NEURL2 | 140825 | 10 | 0 | 10 | |
| TCGA | NEURL2 | 140825 | 46 | 3 | 47 |
Total number of gains: 184; Total number of losses: 25; Total Number of normals: 279.
Somatic mutations of NEURL2:
Generating mutation plots.
Highly correlated genes for NEURL2:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEURL2 | TMEM108 | 0.736338 | 3 | 0 | 3 |
| NEURL2 | KCNK9 | 0.685098 | 3 | 0 | 3 |
| NEURL2 | ZNF576 | 0.68465 | 3 | 0 | 3 |
| NEURL2 | FERD3L | 0.683581 | 4 | 0 | 4 |
| NEURL2 | CAMK2B | 0.667039 | 3 | 0 | 3 |
| NEURL2 | GPR17 | 0.666149 | 4 | 0 | 4 |
| NEURL2 | XIRP1 | 0.665537 | 3 | 0 | 3 |
| NEURL2 | HTR6 | 0.650078 | 3 | 0 | 3 |
| NEURL2 | SHISA7 | 0.648624 | 3 | 0 | 3 |
| NEURL2 | GPRC5C | 0.646117 | 3 | 0 | 3 |
| NEURL2 | ACTL6B | 0.64528 | 3 | 0 | 3 |
| NEURL2 | BTBD19 | 0.644825 | 3 | 0 | 3 |
| NEURL2 | SYCE3 | 0.64218 | 3 | 0 | 3 |
| NEURL2 | RTBDN | 0.639164 | 3 | 0 | 3 |
| NEURL2 | LMX1B | 0.638313 | 4 | 0 | 3 |
| NEURL2 | TPO | 0.637762 | 3 | 0 | 3 |
| NEURL2 | SV2C | 0.635308 | 3 | 0 | 3 |
| NEURL2 | LRRN4 | 0.627108 | 4 | 0 | 3 |
| NEURL2 | ANKRD53 | 0.626026 | 3 | 0 | 3 |
| NEURL2 | CIB2 | 0.620162 | 3 | 0 | 3 |
For details and further investigation, click here
