| Full name: TNF alpha induced protein 8 like 2 | Alias Symbol: FLJ23467 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 79626 | HGNC ID: HGNC:26277 | Ensembl Gene: ENSG00000163154 | OMIM ID: 612112 |
| Drug and gene relationship at DGIdb | |||
Expression of TNFAIP8L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFAIP8L2 | 79626 | 223583_at | -0.0383 | 0.9548 | |
| GSE26886 | TNFAIP8L2 | 79626 | 223583_at | -0.0999 | 0.6531 | |
| GSE45670 | TNFAIP8L2 | 79626 | 223583_at | -0.1731 | 0.3085 | |
| GSE53622 | TNFAIP8L2 | 79626 | 3312 | -0.1533 | 0.4615 | |
| GSE53624 | TNFAIP8L2 | 79626 | 3312 | -0.1151 | 0.5352 | |
| GSE63941 | TNFAIP8L2 | 79626 | 223583_at | 0.2436 | 0.1402 | |
| GSE77861 | TNFAIP8L2 | 79626 | 223583_at | -0.2022 | 0.1371 | |
| GSE97050 | TNFAIP8L2 | 79626 | A_23_P46356 | 0.3795 | 0.1721 | |
| SRP064894 | TNFAIP8L2 | 79626 | RNAseq | 1.0754 | 0.0123 | |
| SRP133303 | TNFAIP8L2 | 79626 | RNAseq | -0.0350 | 0.9033 | |
| SRP159526 | TNFAIP8L2 | 79626 | RNAseq | -0.3859 | 0.5979 | |
| SRP193095 | TNFAIP8L2 | 79626 | RNAseq | -0.1483 | 0.4007 | |
| SRP219564 | TNFAIP8L2 | 79626 | RNAseq | 0.9282 | 0.0818 | |
| TCGA | TNFAIP8L2 | 79626 | RNAseq | 0.5000 | 0.0105 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TNFAIP8L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFAIP8L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFAIP8L2 | 79626 | 14 | 0 | 16 | |
| GSE20123 | TNFAIP8L2 | 79626 | 14 | 0 | 16 | |
| GSE43470 | TNFAIP8L2 | 79626 | 6 | 1 | 36 | |
| GSE46452 | TNFAIP8L2 | 79626 | 2 | 1 | 56 | |
| GSE47630 | TNFAIP8L2 | 79626 | 14 | 0 | 26 | |
| GSE54993 | TNFAIP8L2 | 79626 | 0 | 4 | 66 | |
| GSE54994 | TNFAIP8L2 | 79626 | 15 | 0 | 38 | |
| GSE60625 | TNFAIP8L2 | 79626 | 0 | 0 | 11 | |
| GSE74703 | TNFAIP8L2 | 79626 | 6 | 1 | 29 | |
| GSE74704 | TNFAIP8L2 | 79626 | 7 | 0 | 13 | |
| TCGA | TNFAIP8L2 | 79626 | 37 | 2 | 57 |
Total number of gains: 115; Total number of losses: 9; Total Number of normals: 364.
Somatic mutations of TNFAIP8L2:
Generating mutation plots.
Highly correlated genes for TNFAIP8L2:
Showing top 20/495 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFAIP8L2 | BIN2 | 0.829322 | 6 | 0 | 6 |
| TNFAIP8L2 | SNX20 | 0.823804 | 5 | 0 | 5 |
| TNFAIP8L2 | CD79B | 0.794462 | 4 | 0 | 4 |
| TNFAIP8L2 | MPEG1 | 0.791413 | 5 | 0 | 5 |
| TNFAIP8L2 | TNFSF8 | 0.78585 | 4 | 0 | 4 |
| TNFAIP8L2 | CST7 | 0.77418 | 6 | 0 | 6 |
| TNFAIP8L2 | GPR65 | 0.768122 | 6 | 0 | 6 |
| TNFAIP8L2 | NCKAP1L | 0.768058 | 6 | 0 | 5 |
| TNFAIP8L2 | LILRB5 | 0.763825 | 3 | 0 | 3 |
| TNFAIP8L2 | CCR4 | 0.754367 | 4 | 0 | 4 |
| TNFAIP8L2 | ARHGDIB | 0.752197 | 6 | 0 | 6 |
| TNFAIP8L2 | FGF6 | 0.751057 | 3 | 0 | 3 |
| TNFAIP8L2 | SLA | 0.750355 | 6 | 0 | 6 |
| TNFAIP8L2 | PREX1 | 0.748372 | 3 | 0 | 3 |
| TNFAIP8L2 | TAGAP | 0.748351 | 5 | 0 | 5 |
| TNFAIP8L2 | NEDD9 | 0.747686 | 3 | 0 | 3 |
| TNFAIP8L2 | GPR171 | 0.747601 | 5 | 0 | 5 |
| TNFAIP8L2 | C19orf38 | 0.747224 | 3 | 0 | 3 |
| TNFAIP8L2 | CORO1A | 0.746575 | 7 | 0 | 6 |
| TNFAIP8L2 | AOAH | 0.745495 | 6 | 0 | 5 |
For details and further investigation, click here
