SNX32

 

Full name: sorting nexin 32 Alias Symbol: FLJ30934
Type: protein-coding gene Cytoband: 11q13.1
Entrez ID: 254122 HGNC ID: HGNC:26423 Ensembl Gene: ENSG00000172803 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of SNX32:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SNX32 254122 231194_at -0.1244 0.6938
GSE26886 SNX32 254122 231194_at -0.0089 0.9580
GSE45670 SNX32 254122 231194_at 0.1999 0.0097
GSE53622 SNX32 254122 3759 -0.0736 0.3725
GSE53624 SNX32 254122 3759 -0.2888 0.0000
GSE63941 SNX32 254122 231194_at 0.3945 0.0967
GSE77861 SNX32 254122 231194_at 0.0285 0.8565
SRP133303 SNX32 254122 RNAseq -1.0454 0.0010
TCGA SNX32 254122 RNAseq -0.7216 0.2478

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by SNX32 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SNX32:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SNX32 254122 8 5 17
GSE20123 SNX32 254122 8 5 17
GSE43470 SNX32 254122 6 1 36
GSE46452 SNX32 254122 11 3 45
GSE47630 SNX32 254122 7 5 28
GSE54993 SNX32 254122 3 0 67
GSE54994 SNX32 254122 7 5 41
GSE60625 SNX32 254122 0 3 8
GSE74703 SNX32 254122 4 0 32
GSE74704 SNX32 254122 6 3 11
TCGA SNX32 254122 23 7 66

Total number of gains: 83; Total number of losses: 37; Total Number of normals: 368.  


 

Somatic mutations of SNX32:

 

Generating mutation plots.

 

Highly correlated genes for SNX32:

 

Showing top 20/163 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SNX32DMWD0.710531404
SNX32CNGB30.69829303
SNX32SPATA240.690112303
SNX32NXPH30.676536504
SNX32CRLF20.674802303
SNX32SLC25A350.667092303
SNX32SSUH20.66449303
SNX32PTPN180.657214303
SNX32TSGA130.656166303
SNX32KCNIP2-AS10.65264303
SNX32AMHR20.649387403
SNX32TPBGL0.647552303
SNX32KIR2DS50.646656303
SNX32PRB10.644947403
SNX32ACACB0.637939505
SNX32NUP210L0.636781303
SNX32C1orf1050.635973403
SNX32PNPLA20.635257303
SNX32CAMK2B0.634843404
SNX32RNF1330.633954403

For details and further investigation, click here