| Full name: Ras association domain family member 4 | Alias Symbol: AD037|MGC44914 | ||
| Type: protein-coding gene | Cytoband: 10q11.21 | ||
| Entrez ID: 83937 | HGNC ID: HGNC:20793 | Ensembl Gene: ENSG00000107551 | OMIM ID: 610559 |
| Drug and gene relationship at DGIdb | |||
Expression of RASSF4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RASSF4 | 83937 | 226436_at | 0.0335 | 0.9779 | |
| GSE20347 | RASSF4 | 83937 | 221578_at | -0.0166 | 0.8817 | |
| GSE23400 | RASSF4 | 83937 | 221578_at | -0.0550 | 0.0869 | |
| GSE26886 | RASSF4 | 83937 | 221578_at | -0.0414 | 0.7811 | |
| GSE29001 | RASSF4 | 83937 | 221578_at | -0.1303 | 0.4404 | |
| GSE38129 | RASSF4 | 83937 | 221578_at | -0.0708 | 0.3452 | |
| GSE45670 | RASSF4 | 83937 | 226436_at | -0.3651 | 0.2562 | |
| GSE53622 | RASSF4 | 83937 | 73334 | 0.6715 | 0.0000 | |
| GSE53624 | RASSF4 | 83937 | 73334 | 0.6585 | 0.0000 | |
| GSE63941 | RASSF4 | 83937 | 221578_at | 0.0586 | 0.7762 | |
| GSE77861 | RASSF4 | 83937 | 221578_at | -0.0392 | 0.7153 | |
| GSE97050 | RASSF4 | 83937 | A_24_P295590 | 0.3509 | 0.2987 | |
| SRP007169 | RASSF4 | 83937 | RNAseq | 3.6363 | 0.0001 | |
| SRP008496 | RASSF4 | 83937 | RNAseq | 3.0789 | 0.0000 | |
| SRP064894 | RASSF4 | 83937 | RNAseq | 1.1907 | 0.0003 | |
| SRP133303 | RASSF4 | 83937 | RNAseq | 0.5968 | 0.0126 | |
| SRP159526 | RASSF4 | 83937 | RNAseq | -0.1208 | 0.7526 | |
| SRP193095 | RASSF4 | 83937 | RNAseq | 0.5151 | 0.1005 | |
| SRP219564 | RASSF4 | 83937 | RNAseq | 0.5256 | 0.2356 | |
| TCGA | RASSF4 | 83937 | RNAseq | -0.0891 | 0.4669 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by RASSF4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RASSF4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RASSF4 | 83937 | 3 | 5 | 22 | |
| GSE20123 | RASSF4 | 83937 | 3 | 5 | 22 | |
| GSE43470 | RASSF4 | 83937 | 1 | 6 | 36 | |
| GSE46452 | RASSF4 | 83937 | 0 | 13 | 46 | |
| GSE47630 | RASSF4 | 83937 | 4 | 12 | 24 | |
| GSE54993 | RASSF4 | 83937 | 9 | 0 | 61 | |
| GSE54994 | RASSF4 | 83937 | 2 | 10 | 41 | |
| GSE60625 | RASSF4 | 83937 | 0 | 0 | 11 | |
| GSE74703 | RASSF4 | 83937 | 1 | 3 | 32 | |
| GSE74704 | RASSF4 | 83937 | 2 | 4 | 14 | |
| TCGA | RASSF4 | 83937 | 17 | 17 | 62 |
Total number of gains: 42; Total number of losses: 75; Total Number of normals: 371.
Somatic mutations of RASSF4:
Generating mutation plots.
Highly correlated genes for RASSF4:
Showing top 20/597 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RASSF4 | C1QA | 0.799876 | 6 | 0 | 6 |
| RASSF4 | FCGR3A | 0.779983 | 3 | 0 | 3 |
| RASSF4 | TFEC | 0.775116 | 5 | 0 | 5 |
| RASSF4 | C1QB | 0.766025 | 6 | 0 | 6 |
| RASSF4 | C3AR1 | 0.753931 | 5 | 0 | 4 |
| RASSF4 | RGS3 | 0.752805 | 3 | 0 | 3 |
| RASSF4 | CERKL | 0.746513 | 3 | 0 | 3 |
| RASSF4 | TMEM140 | 0.737275 | 6 | 0 | 6 |
| RASSF4 | ANGPTL6 | 0.736336 | 3 | 0 | 3 |
| RASSF4 | SLC43A2 | 0.734376 | 4 | 0 | 4 |
| RASSF4 | GPR141 | 0.732208 | 3 | 0 | 3 |
| RASSF4 | TNFRSF1B | 0.732181 | 6 | 0 | 6 |
| RASSF4 | FCER1G | 0.730171 | 5 | 0 | 5 |
| RASSF4 | ITGB2 | 0.729635 | 6 | 0 | 6 |
| RASSF4 | SLC41A2 | 0.727575 | 4 | 0 | 4 |
| RASSF4 | CD53 | 0.727234 | 4 | 0 | 4 |
| RASSF4 | MILR1 | 0.72122 | 5 | 0 | 5 |
| RASSF4 | TIRAP | 0.720648 | 3 | 0 | 3 |
| RASSF4 | CD84 | 0.717994 | 8 | 0 | 7 |
| RASSF4 | SLC15A3 | 0.716869 | 5 | 0 | 4 |
For details and further investigation, click here
