RPL23

 

Full name: ribosomal protein L23 Alias Symbol: rpL17|L23
Type: protein-coding gene Cytoband: 17q12
Entrez ID: 9349 HGNC ID: HGNC:10316 Ensembl Gene: ENSG00000125691 OMIM ID: 603662
Drug and gene relationship at DGIdb

 

Expression of RPL23:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 RPL23 9349 75400 -0.0556 0.4209
GSE53624 RPL23 9349 53296 0.0295 0.6277
GSE97050 RPL23 9349 A_32_P30710 -0.2820 0.3954
SRP007169 RPL23 9349 RNAseq -0.5391 0.1373
SRP008496 RPL23 9349 RNAseq -0.5158 0.0342
SRP064894 RPL23 9349 RNAseq -0.2056 0.4967
SRP133303 RPL23 9349 RNAseq -0.3917 0.0009
SRP159526 RPL23 9349 RNAseq -0.5271 0.0791
SRP193095 RPL23 9349 RNAseq -0.9561 0.0000
SRP219564 RPL23 9349 RNAseq -0.5811 0.0422
TCGA RPL23 9349 RNAseq 0.0419 0.3336

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by RPL23 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RPL23:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RPL23 9349 7 1 22
GSE20123 RPL23 9349 7 1 22
GSE43470 RPL23 9349 1 1 41
GSE46452 RPL23 9349 34 0 25
GSE47630 RPL23 9349 8 1 31
GSE54993 RPL23 9349 3 4 63
GSE54994 RPL23 9349 8 5 40
GSE60625 RPL23 9349 4 0 7
GSE74703 RPL23 9349 1 0 35
GSE74704 RPL23 9349 4 1 15
TCGA RPL23 9349 19 8 69

Total number of gains: 96; Total number of losses: 22; Total Number of normals: 370.  


 

Somatic mutations of RPL23:

 

Generating mutation plots.

 

Highly correlated genes for RPL23:

 

Showing all 12 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RPL23RPL190.72323303
RPL23RPS170.648183403
RPL23RPL23A0.635247403
RPL23RPS200.623271404
RPL23RPS80.619056303
RPL23RPS180.612919303
RPL23RPL120.601563303
RPL23RPL360.586785303
RPL23RPS100.569569403
RPL23RPL130.565538303
RPL23RPL270.556147403
RPL23RPL110.547508403

For details and further investigation, click here