| Full name: ribosomal protein L23a | Alias Symbol: L23A | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 6147 | HGNC ID: HGNC:10317 | Ensembl Gene: ENSG00000198242 | OMIM ID: 602326 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL23A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL23A | 6147 | 203012_x_at | -0.0543 | 0.7866 | |
| GSE20347 | RPL23A | 6147 | 203012_x_at | 0.0246 | 0.7884 | |
| GSE23400 | RPL23A | 6147 | 203012_x_at | 0.0702 | 0.0903 | |
| GSE26886 | RPL23A | 6147 | 203012_x_at | 0.6527 | 0.0000 | |
| GSE29001 | RPL23A | 6147 | 203012_x_at | -0.1625 | 0.4505 | |
| GSE38129 | RPL23A | 6147 | 203012_x_at | 0.0329 | 0.5860 | |
| GSE45670 | RPL23A | 6147 | 203012_x_at | -0.1359 | 0.2574 | |
| GSE53622 | RPL23A | 6147 | 2834 | -0.2996 | 0.0000 | |
| GSE53624 | RPL23A | 6147 | 2834 | -0.0308 | 0.5566 | |
| GSE63941 | RPL23A | 6147 | 203012_x_at | 0.4052 | 0.0223 | |
| GSE77861 | RPL23A | 6147 | 203012_x_at | 0.0543 | 0.6658 | |
| GSE97050 | RPL23A | 6147 | A_23_P29747 | -0.4482 | 0.2746 | |
| SRP007169 | RPL23A | 6147 | RNAseq | -0.8160 | 0.0366 | |
| SRP008496 | RPL23A | 6147 | RNAseq | -0.9380 | 0.0001 | |
| SRP064894 | RPL23A | 6147 | RNAseq | -0.1954 | 0.5500 | |
| SRP133303 | RPL23A | 6147 | RNAseq | -0.5061 | 0.0000 | |
| SRP159526 | RPL23A | 6147 | RNAseq | -0.5959 | 0.0088 | |
| SRP193095 | RPL23A | 6147 | RNAseq | -0.8901 | 0.0000 | |
| SRP219564 | RPL23A | 6147 | RNAseq | -0.6932 | 0.0032 | |
| TCGA | RPL23A | 6147 | RNAseq | -0.0213 | 0.6627 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPL23A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL23A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL23A | 6147 | 9 | 1 | 20 | |
| GSE20123 | RPL23A | 6147 | 9 | 1 | 20 | |
| GSE43470 | RPL23A | 6147 | 0 | 1 | 42 | |
| GSE46452 | RPL23A | 6147 | 33 | 1 | 25 | |
| GSE47630 | RPL23A | 6147 | 7 | 1 | 32 | |
| GSE54993 | RPL23A | 6147 | 2 | 3 | 65 | |
| GSE54994 | RPL23A | 6147 | 7 | 6 | 40 | |
| GSE60625 | RPL23A | 6147 | 4 | 0 | 7 | |
| GSE74703 | RPL23A | 6147 | 0 | 1 | 35 | |
| GSE74704 | RPL23A | 6147 | 7 | 1 | 12 | |
| TCGA | RPL23A | 6147 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of RPL23A:
Generating mutation plots.
Highly correlated genes for RPL23A:
Showing top 20/215 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL23A | RPL18A | 0.683103 | 3 | 0 | 3 |
| RPL23A | PTPRM | 0.678288 | 3 | 0 | 3 |
| RPL23A | FKBP5 | 0.676109 | 3 | 0 | 3 |
| RPL23A | RPL27 | 0.674408 | 10 | 0 | 9 |
| RPL23A | IDS | 0.671356 | 3 | 0 | 3 |
| RPL23A | ZCCHC7 | 0.667164 | 3 | 0 | 3 |
| RPL23A | RAB20 | 0.66122 | 4 | 0 | 3 |
| RPL23A | FAM192A | 0.660111 | 3 | 0 | 3 |
| RPL23A | RPS15A | 0.659375 | 11 | 0 | 10 |
| RPL23A | RPS13 | 0.658993 | 4 | 0 | 4 |
| RPL23A | RPL31 | 0.653016 | 11 | 0 | 9 |
| RPL23A | RPS17 | 0.650484 | 11 | 0 | 9 |
| RPL23A | RPL19 | 0.649397 | 13 | 0 | 12 |
| RPL23A | UBA2 | 0.649307 | 3 | 0 | 3 |
| RPL23A | BUD31 | 0.643573 | 5 | 0 | 4 |
| RPL23A | RPS27 | 0.638936 | 12 | 0 | 11 |
| RPL23A | RPL23 | 0.635247 | 4 | 0 | 3 |
| RPL23A | DNAJC1 | 0.624912 | 3 | 0 | 3 |
| RPL23A | CXorf40A | 0.6224 | 3 | 0 | 3 |
| RPL23A | RPS10 | 0.621026 | 10 | 0 | 7 |
For details and further investigation, click here
