| Full name: ribosomal protein L11 | Alias Symbol: L11|uL5 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 6135 | HGNC ID: HGNC:10301 | Ensembl Gene: ENSG00000142676 | OMIM ID: 604175 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL11 | 6135 | 200010_at | -0.2234 | 0.2830 | |
| GSE20347 | RPL11 | 6135 | 200010_at | -0.2555 | 0.0294 | |
| GSE23400 | RPL11 | 6135 | 200010_at | -0.0510 | 0.4230 | |
| GSE26886 | RPL11 | 6135 | 200010_at | 0.2078 | 0.3749 | |
| GSE29001 | RPL11 | 6135 | 200010_at | -0.3625 | 0.4892 | |
| GSE38129 | RPL11 | 6135 | 200010_at | -0.2109 | 0.0152 | |
| GSE45670 | RPL11 | 6135 | 200010_at | -0.2462 | 0.0023 | |
| GSE53622 | RPL11 | 6135 | 121228 | -0.4854 | 0.0000 | |
| GSE53624 | RPL11 | 6135 | 121228 | -0.2788 | 0.0000 | |
| GSE63941 | RPL11 | 6135 | 200010_at | 0.4592 | 0.0178 | |
| GSE77861 | RPL11 | 6135 | 200010_at | -0.3834 | 0.0280 | |
| GSE97050 | RPL11 | 6135 | A_23_P62605 | -0.3801 | 0.4031 | |
| SRP007169 | RPL11 | 6135 | RNAseq | -1.1144 | 0.0004 | |
| SRP008496 | RPL11 | 6135 | RNAseq | -1.0622 | 0.0000 | |
| SRP064894 | RPL11 | 6135 | RNAseq | -0.3445 | 0.2797 | |
| SRP133303 | RPL11 | 6135 | RNAseq | -0.4600 | 0.0021 | |
| SRP159526 | RPL11 | 6135 | RNAseq | -0.6916 | 0.0000 | |
| SRP193095 | RPL11 | 6135 | RNAseq | -1.0465 | 0.0000 | |
| SRP219564 | RPL11 | 6135 | RNAseq | -0.6638 | 0.0296 | |
| TCGA | RPL11 | 6135 | RNAseq | -0.0475 | 0.2901 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RPL11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL11 | 6135 | 0 | 5 | 25 | |
| GSE20123 | RPL11 | 6135 | 0 | 4 | 26 | |
| GSE43470 | RPL11 | 6135 | 2 | 6 | 35 | |
| GSE46452 | RPL11 | 6135 | 5 | 1 | 53 | |
| GSE47630 | RPL11 | 6135 | 8 | 3 | 29 | |
| GSE54993 | RPL11 | 6135 | 2 | 1 | 67 | |
| GSE54994 | RPL11 | 6135 | 11 | 4 | 38 | |
| GSE60625 | RPL11 | 6135 | 0 | 0 | 11 | |
| GSE74703 | RPL11 | 6135 | 1 | 4 | 31 | |
| GSE74704 | RPL11 | 6135 | 0 | 0 | 20 | |
| TCGA | RPL11 | 6135 | 9 | 24 | 63 |
Total number of gains: 38; Total number of losses: 52; Total Number of normals: 398.
Somatic mutations of RPL11:
Generating mutation plots.
Highly correlated genes for RPL11:
Showing top 20/281 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL11 | RPL10A | 0.705667 | 11 | 0 | 9 |
| RPL11 | NACA | 0.703855 | 11 | 0 | 11 |
| RPL11 | RPS5 | 0.672625 | 11 | 0 | 9 |
| RPL11 | RPL29 | 0.671477 | 12 | 0 | 10 |
| RPL11 | RPS9 | 0.665501 | 11 | 0 | 9 |
| RPL11 | BRK1 | 0.660616 | 4 | 0 | 4 |
| RPL11 | RPS3A | 0.658597 | 3 | 0 | 3 |
| RPL11 | RPS18 | 0.654167 | 13 | 0 | 12 |
| RPL11 | RPL34 | 0.647998 | 12 | 0 | 9 |
| RPL11 | SHROOM3 | 0.647955 | 4 | 0 | 4 |
| RPL11 | RPL9 | 0.647854 | 10 | 0 | 8 |
| RPL11 | N4BP3 | 0.641637 | 4 | 0 | 4 |
| RPL11 | RPL6 | 0.640377 | 13 | 0 | 9 |
| RPL11 | DCTN3 | 0.637147 | 6 | 0 | 6 |
| RPL11 | RPS14 | 0.633134 | 11 | 0 | 9 |
| RPL11 | PFDN5 | 0.630235 | 12 | 0 | 7 |
| RPL11 | RPS24 | 0.629939 | 12 | 0 | 11 |
| RPL11 | GSTO2 | 0.618349 | 4 | 0 | 3 |
| RPL11 | RPS6 | 0.61583 | 11 | 0 | 8 |
| RPL11 | DHRS3 | 0.613891 | 4 | 0 | 3 |
For details and further investigation, click here
