| Full name: ribosomal protein L27 | Alias Symbol: L27 | ||
| Type: protein-coding gene | Cytoband: 17q21 | ||
| Entrez ID: 6155 | HGNC ID: HGNC:10328 | Ensembl Gene: ENSG00000131469 | OMIM ID: 607526 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL27 | 6155 | 200025_s_at | -0.0344 | 0.8641 | |
| GSE20347 | RPL27 | 6155 | 200025_s_at | 0.0330 | 0.7047 | |
| GSE23400 | RPL27 | 6155 | 200025_s_at | 0.1024 | 0.0229 | |
| GSE26886 | RPL27 | 6155 | 200025_s_at | 0.3646 | 0.0013 | |
| GSE29001 | RPL27 | 6155 | 200025_s_at | -0.0968 | 0.5869 | |
| GSE38129 | RPL27 | 6155 | 200025_s_at | 0.0260 | 0.6740 | |
| GSE45670 | RPL27 | 6155 | 200025_s_at | -0.0706 | 0.3417 | |
| GSE53622 | RPL27 | 6155 | 87624 | -0.3576 | 0.0000 | |
| GSE53624 | RPL27 | 6155 | 87624 | -0.1521 | 0.0183 | |
| GSE63941 | RPL27 | 6155 | 200025_s_at | 0.1009 | 0.4055 | |
| GSE77861 | RPL27 | 6155 | 200025_s_at | 0.0191 | 0.8479 | |
| GSE97050 | RPL27 | 6155 | A_23_P141389 | -0.2824 | 0.4164 | |
| SRP007169 | RPL27 | 6155 | RNAseq | -0.7486 | 0.0170 | |
| SRP008496 | RPL27 | 6155 | RNAseq | -0.7695 | 0.0001 | |
| SRP064894 | RPL27 | 6155 | RNAseq | -0.0129 | 0.9682 | |
| SRP133303 | RPL27 | 6155 | RNAseq | -0.4160 | 0.0008 | |
| SRP159526 | RPL27 | 6155 | RNAseq | -0.5393 | 0.0048 | |
| SRP193095 | RPL27 | 6155 | RNAseq | -0.9273 | 0.0000 | |
| SRP219564 | RPL27 | 6155 | RNAseq | -0.5898 | 0.0237 | |
| TCGA | RPL27 | 6155 | RNAseq | 0.0493 | 0.3005 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPL27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL27 | 6155 | 6 | 2 | 22 | |
| GSE20123 | RPL27 | 6155 | 6 | 2 | 22 | |
| GSE43470 | RPL27 | 6155 | 1 | 2 | 40 | |
| GSE46452 | RPL27 | 6155 | 34 | 0 | 25 | |
| GSE47630 | RPL27 | 6155 | 8 | 1 | 31 | |
| GSE54993 | RPL27 | 6155 | 3 | 4 | 63 | |
| GSE54994 | RPL27 | 6155 | 8 | 5 | 40 | |
| GSE60625 | RPL27 | 6155 | 4 | 0 | 7 | |
| GSE74703 | RPL27 | 6155 | 1 | 1 | 34 | |
| GSE74704 | RPL27 | 6155 | 4 | 1 | 15 | |
| TCGA | RPL27 | 6155 | 22 | 7 | 67 |
Total number of gains: 97; Total number of losses: 25; Total Number of normals: 366.
Somatic mutations of RPL27:
Generating mutation plots.
Highly correlated genes for RPL27:
Showing top 20/160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL27 | RPS13 | 0.760509 | 3 | 0 | 3 |
| RPL27 | EIF3M | 0.724392 | 3 | 0 | 3 |
| RPL27 | SNX7 | 0.693113 | 3 | 0 | 3 |
| RPL27 | RPL23A | 0.674408 | 10 | 0 | 9 |
| RPL27 | ELP3 | 0.666932 | 3 | 0 | 3 |
| RPL27 | MTPN | 0.657694 | 3 | 0 | 3 |
| RPL27 | RPS28 | 0.657319 | 6 | 0 | 5 |
| RPL27 | BTG1 | 0.650738 | 3 | 0 | 3 |
| RPL27 | TMEM126A | 0.647829 | 3 | 0 | 3 |
| RPL27 | RPL19 | 0.626606 | 10 | 0 | 9 |
| RPL27 | UEVLD | 0.619734 | 3 | 0 | 3 |
| RPL27 | RPS15A | 0.619302 | 11 | 0 | 8 |
| RPL27 | RPS17 | 0.616012 | 11 | 0 | 7 |
| RPL27 | RPS10 | 0.612764 | 9 | 0 | 7 |
| RPL27 | C12orf29 | 0.612553 | 4 | 0 | 3 |
| RPL27 | RPL32 | 0.601561 | 6 | 0 | 3 |
| RPL27 | RPL41 | 0.60057 | 9 | 0 | 8 |
| RPL27 | ATF6 | 0.600404 | 4 | 0 | 3 |
| RPL27 | ARFGAP3 | 0.597128 | 4 | 0 | 3 |
| RPL27 | PDZD8 | 0.596197 | 4 | 0 | 3 |
For details and further investigation, click here
