| Full name: ribosomal protein L36 | Alias Symbol: DKFZp566B023|L36 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 25873 | HGNC ID: HGNC:13631 | Ensembl Gene: ENSG00000130255 | OMIM ID: 617893 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPL36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL36 | 25873 | 219762_s_at | -0.1107 | 0.7734 | |
| GSE20347 | RPL36 | 25873 | 219762_s_at | -0.1488 | 0.2431 | |
| GSE23400 | RPL36 | 25873 | 219762_s_at | -0.0431 | 0.6726 | |
| GSE26886 | RPL36 | 25873 | 219762_s_at | 0.6663 | 0.0128 | |
| GSE29001 | RPL36 | 25873 | 219762_s_at | -0.2528 | 0.4333 | |
| GSE38129 | RPL36 | 25873 | 219762_s_at | 0.0979 | 0.4063 | |
| GSE45670 | RPL36 | 25873 | 219762_s_at | -0.0343 | 0.7814 | |
| GSE53622 | RPL36 | 25873 | 9948 | -0.3453 | 0.0000 | |
| GSE53624 | RPL36 | 25873 | 9948 | 0.0968 | 0.0561 | |
| GSE63941 | RPL36 | 25873 | 219762_s_at | 0.0136 | 0.9735 | |
| GSE77861 | RPL36 | 25873 | 219762_s_at | -0.0711 | 0.8135 | |
| GSE97050 | RPL36 | 25873 | A_23_P153383 | -0.1431 | 0.6467 | |
| SRP007169 | RPL36 | 25873 | RNAseq | -1.1201 | 0.0015 | |
| SRP008496 | RPL36 | 25873 | RNAseq | -0.8410 | 0.0000 | |
| SRP064894 | RPL36 | 25873 | RNAseq | 0.2314 | 0.6047 | |
| SRP133303 | RPL36 | 25873 | RNAseq | -0.4737 | 0.0363 | |
| SRP159526 | RPL36 | 25873 | RNAseq | -0.5761 | 0.0016 | |
| SRP193095 | RPL36 | 25873 | RNAseq | -0.8173 | 0.0000 | |
| SRP219564 | RPL36 | 25873 | RNAseq | -0.0942 | 0.7312 | |
| TCGA | RPL36 | 25873 | RNAseq | 0.0516 | 0.3467 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPL36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL36 | 25873 | 5 | 3 | 22 | |
| GSE20123 | RPL36 | 25873 | 4 | 2 | 24 | |
| GSE43470 | RPL36 | 25873 | 2 | 6 | 35 | |
| GSE46452 | RPL36 | 25873 | 47 | 1 | 11 | |
| GSE47630 | RPL36 | 25873 | 5 | 7 | 28 | |
| GSE54993 | RPL36 | 25873 | 16 | 3 | 51 | |
| GSE54994 | RPL36 | 25873 | 6 | 16 | 31 | |
| GSE60625 | RPL36 | 25873 | 9 | 0 | 2 | |
| GSE74703 | RPL36 | 25873 | 2 | 4 | 30 | |
| GSE74704 | RPL36 | 25873 | 1 | 2 | 17 | |
| TCGA | RPL36 | 25873 | 10 | 18 | 68 |
Total number of gains: 107; Total number of losses: 62; Total Number of normals: 319.
Somatic mutations of RPL36:
Generating mutation plots.
Highly correlated genes for RPL36:
Showing top 20/79 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL36 | DNAJC4 | 0.72859 | 3 | 0 | 3 |
| RPL36 | RPL18A | 0.67447 | 3 | 0 | 3 |
| RPL36 | RHPN1 | 0.656521 | 3 | 0 | 3 |
| RPL36 | RPL39 | 0.636522 | 6 | 0 | 4 |
| RPL36 | RPL12 | 0.635787 | 11 | 0 | 11 |
| RPL36 | RPS15 | 0.632005 | 12 | 0 | 10 |
| RPL36 | RPS28 | 0.631151 | 11 | 0 | 9 |
| RPL36 | RPL31 | 0.624251 | 10 | 0 | 10 |
| RPL36 | RPL35 | 0.623793 | 11 | 0 | 9 |
| RPL36 | RPS13 | 0.621465 | 4 | 0 | 4 |
| RPL36 | PHPT1 | 0.61462 | 3 | 0 | 3 |
| RPL36 | RPS5 | 0.604012 | 11 | 0 | 9 |
| RPL36 | UBA52 | 0.603134 | 12 | 0 | 9 |
| RPL36 | ATAD3A | 0.60266 | 3 | 0 | 3 |
| RPL36 | ITIH4 | 0.602532 | 3 | 0 | 3 |
| RPL36 | RPL13 | 0.593682 | 3 | 0 | 3 |
| RPL36 | GLB1L2 | 0.593681 | 3 | 0 | 3 |
| RPL36 | EEF2 | 0.592006 | 10 | 0 | 8 |
| RPL36 | RPL23 | 0.586785 | 3 | 0 | 3 |
| RPL36 | DNM2 | 0.584881 | 4 | 0 | 3 |
For details and further investigation, click here
