| Full name: ribosomal protein S18 | Alias Symbol: KE3|KE-3|HKE3|S18 | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 6222 | HGNC ID: HGNC:10401 | Ensembl Gene: ENSG00000231500 | OMIM ID: 180473 |
| Drug and gene relationship at DGIdb | |||
Expression of RPS18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS18 | 6222 | 201049_s_at | -0.0218 | 0.9426 | |
| GSE20347 | RPS18 | 6222 | 201049_s_at | -0.1556 | 0.0363 | |
| GSE23400 | RPS18 | 6222 | 201049_s_at | -0.0376 | 0.5364 | |
| GSE26886 | RPS18 | 6222 | 201049_s_at | -0.0424 | 0.7341 | |
| GSE29001 | RPS18 | 6222 | 201049_s_at | -0.5130 | 0.0799 | |
| GSE38129 | RPS18 | 6222 | 201049_s_at | -0.0425 | 0.5616 | |
| GSE45670 | RPS18 | 6222 | 201049_s_at | -0.2379 | 0.0028 | |
| GSE53622 | RPS18 | 6222 | 17903 | -0.2457 | 0.0045 | |
| GSE53624 | RPS18 | 6222 | 17903 | -0.2737 | 0.0000 | |
| GSE63941 | RPS18 | 6222 | 201049_s_at | 0.1863 | 0.1044 | |
| GSE77861 | RPS18 | 6222 | 201049_s_at | -0.2316 | 0.1165 | |
| GSE97050 | RPS18 | 6222 | A_23_P214666 | -0.4364 | 0.3091 | |
| SRP007169 | RPS18 | 6222 | RNAseq | -1.4628 | 0.0002 | |
| SRP008496 | RPS18 | 6222 | RNAseq | -1.3354 | 0.0000 | |
| SRP064894 | RPS18 | 6222 | RNAseq | -0.5852 | 0.0462 | |
| SRP133303 | RPS18 | 6222 | RNAseq | -0.8156 | 0.0000 | |
| SRP159526 | RPS18 | 6222 | RNAseq | -0.8047 | 0.0050 | |
| SRP193095 | RPS18 | 6222 | RNAseq | -1.3101 | 0.0000 | |
| SRP219564 | RPS18 | 6222 | RNAseq | -0.5846 | 0.1550 | |
| TCGA | RPS18 | 6222 | RNAseq | 0.0278 | 0.6892 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RPS18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS18 | 6222 | 5 | 0 | 25 | |
| GSE20123 | RPS18 | 6222 | 5 | 0 | 25 | |
| GSE43470 | RPS18 | 6222 | 4 | 1 | 38 | |
| GSE46452 | RPS18 | 6222 | 2 | 9 | 48 | |
| GSE47630 | RPS18 | 6222 | 8 | 4 | 28 | |
| GSE54993 | RPS18 | 6222 | 3 | 1 | 66 | |
| GSE54994 | RPS18 | 6222 | 11 | 4 | 38 | |
| GSE60625 | RPS18 | 6222 | 1 | 0 | 10 | |
| GSE74703 | RPS18 | 6222 | 4 | 0 | 32 | |
| GSE74704 | RPS18 | 6222 | 2 | 0 | 18 | |
| TCGA | RPS18 | 6222 | 15 | 16 | 65 |
Total number of gains: 60; Total number of losses: 35; Total Number of normals: 393.
Somatic mutations of RPS18:
Generating mutation plots.
Highly correlated genes for RPS18:
Showing top 20/161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS18 | RPL12 | 0.692998 | 9 | 0 | 8 |
| RPS18 | RPLP0 | 0.679626 | 11 | 0 | 9 |
| RPS18 | RPL10A | 0.668685 | 12 | 0 | 10 |
| RPS18 | RPL3 | 0.665145 | 11 | 0 | 9 |
| RPS18 | GABARAP | 0.659247 | 4 | 0 | 3 |
| RPS18 | RPL18 | 0.654192 | 13 | 0 | 11 |
| RPS18 | RPL11 | 0.654167 | 13 | 0 | 12 |
| RPS18 | RPL15 | 0.648348 | 12 | 0 | 10 |
| RPS18 | RPS5 | 0.644944 | 12 | 0 | 10 |
| RPS18 | RPS10 | 0.640605 | 11 | 0 | 8 |
| RPS18 | NACA | 0.638299 | 11 | 0 | 9 |
| RPS18 | RPL6 | 0.626521 | 13 | 0 | 10 |
| RPS18 | RPS14 | 0.62523 | 12 | 0 | 9 |
| RPS18 | RPL29 | 0.622535 | 12 | 0 | 10 |
| RPS18 | CYC1 | 0.620979 | 3 | 0 | 3 |
| RPS18 | RPS13 | 0.619926 | 4 | 0 | 3 |
| RPS18 | RPL23 | 0.612919 | 3 | 0 | 3 |
| RPS18 | RPL18A | 0.612278 | 4 | 0 | 3 |
| RPS18 | RPLP1 | 0.610748 | 8 | 0 | 4 |
| RPS18 | RPL31 | 0.610312 | 10 | 0 | 8 |
For details and further investigation, click here
