RXFP2

 

Full name: relaxin family peptide receptor 2 Alias Symbol: GREAT|GPR106|INSL3R|RXFPR2
Type: protein-coding gene Cytoband: 13q13.1
Entrez ID: 122042 HGNC ID: HGNC:17318 Ensembl Gene: ENSG00000133105 OMIM ID: 606655
Drug and gene relationship at DGIdb

 

Expression of RXFP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RXFP2 122042 1553326_at -0.0204 0.9409
GSE26886 RXFP2 122042 1553326_at -0.0580 0.5904
GSE45670 RXFP2 122042 1553326_at -0.1017 0.2345
GSE53622 RXFP2 122042 888 0.1677 0.0637
GSE53624 RXFP2 122042 888 0.3479 0.0027
GSE63941 RXFP2 122042 1553326_at 0.0849 0.5412
GSE77861 RXFP2 122042 1553326_at -0.0536 0.5285

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by RXFP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RXFP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RXFP2 122042 1 14 15
GSE20123 RXFP2 122042 1 13 16
GSE43470 RXFP2 122042 2 12 29
GSE46452 RXFP2 122042 0 33 26
GSE47630 RXFP2 122042 2 27 11
GSE54993 RXFP2 122042 12 2 56
GSE54994 RXFP2 122042 2 15 36
GSE60625 RXFP2 122042 0 3 8
GSE74703 RXFP2 122042 2 9 25
GSE74704 RXFP2 122042 0 11 9
TCGA RXFP2 122042 8 37 51

Total number of gains: 30; Total number of losses: 176; Total Number of normals: 282.  

 

Somatic mutations of RXFP2:

 

Generating mutation plots.

 

Highly correlated genes for RXFP2:

 

Showing all 12 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RXFP2CALML60.589584303
RXFP2CD40.582946303
RXFP2MYBPC30.581353303
RXFP2LINC013430.555929403
RXFP2TTLL20.545406403
RXFP2TESPA10.540078503
RXFP2LINC003960.539925403
RXFP2MOS0.538878403
RXFP2INSL30.538124403
RXFP2PPP1R170.531845403
RXFP2KRT730.515398403
RXFP2LINC004700.513284403

For details and further investigation, click here