| Full name: keratin 73 | Alias Symbol: KRT6IRS3|K6IRS3 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 319101 | HGNC ID: HGNC:28928 | Ensembl Gene: ENSG00000186049 | OMIM ID: 608247 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT73:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT73 | 319101 | 237507_at | -0.1257 | 0.6359 | |
| GSE26886 | KRT73 | 319101 | 237507_at | -0.2733 | 0.1164 | |
| GSE45670 | KRT73 | 319101 | 237507_at | -0.0909 | 0.4202 | |
| GSE53622 | KRT73 | 319101 | 1288 | 0.1275 | 0.1974 | |
| GSE53624 | KRT73 | 319101 | 1288 | -0.0613 | 0.5795 | |
| GSE63941 | KRT73 | 319101 | 237507_at | 0.1639 | 0.3942 | |
| GSE77861 | KRT73 | 319101 | 237507_at | -0.1966 | 0.0743 | |
| GSE97050 | KRT73 | 319101 | A_33_P3315303 | -0.0137 | 0.9540 | |
| TCGA | KRT73 | 319101 | RNAseq | 0.6756 | 0.5378 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRT73 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT73:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT73 | 319101 | 8 | 1 | 21 | |
| GSE20123 | KRT73 | 319101 | 8 | 1 | 21 | |
| GSE43470 | KRT73 | 319101 | 3 | 0 | 40 | |
| GSE46452 | KRT73 | 319101 | 7 | 1 | 51 | |
| GSE47630 | KRT73 | 319101 | 10 | 2 | 28 | |
| GSE54993 | KRT73 | 319101 | 0 | 5 | 65 | |
| GSE54994 | KRT73 | 319101 | 5 | 1 | 47 | |
| GSE60625 | KRT73 | 319101 | 0 | 0 | 11 | |
| GSE74703 | KRT73 | 319101 | 3 | 0 | 33 | |
| GSE74704 | KRT73 | 319101 | 5 | 1 | 14 | |
| TCGA | KRT73 | 319101 | 13 | 11 | 72 |
Total number of gains: 62; Total number of losses: 23; Total Number of normals: 403.
Somatic mutations of KRT73:
Generating mutation plots.
Highly correlated genes for KRT73:
Showing top 20/273 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT73 | KRTAP10-12 | 0.765174 | 3 | 0 | 3 |
| KRT73 | ACTA2-AS1 | 0.703981 | 3 | 0 | 3 |
| KRT73 | STRA6 | 0.702103 | 3 | 0 | 3 |
| KRT73 | KCTD19 | 0.701936 | 3 | 0 | 3 |
| KRT73 | CREB3L3 | 0.692733 | 3 | 0 | 3 |
| KRT73 | LINC00917 | 0.685006 | 3 | 0 | 3 |
| KRT73 | LINC00930 | 0.681829 | 5 | 0 | 5 |
| KRT73 | BTNL8 | 0.681592 | 3 | 0 | 3 |
| KRT73 | HCN1 | 0.678567 | 3 | 0 | 3 |
| KRT73 | KRTAP5-7 | 0.669204 | 3 | 0 | 3 |
| KRT73 | MAPK4 | 0.664289 | 3 | 0 | 3 |
| KRT73 | RIT2 | 0.661311 | 3 | 0 | 3 |
| KRT73 | LINC01281 | 0.660653 | 3 | 0 | 3 |
| KRT73 | ST3GAL3 | 0.659747 | 4 | 0 | 3 |
| KRT73 | LINC01122 | 0.655204 | 4 | 0 | 3 |
| KRT73 | LINC00523 | 0.651747 | 4 | 0 | 4 |
| KRT73 | ZNF761 | 0.648088 | 3 | 0 | 3 |
| KRT73 | F2RL3 | 0.646055 | 5 | 0 | 5 |
| KRT73 | SIM1 | 0.646034 | 4 | 0 | 3 |
| KRT73 | ACRBP | 0.645876 | 3 | 0 | 3 |
For details and further investigation, click here
