| Full name: protein phosphatase 1 regulatory subunit 17 | Alias Symbol: GSBS | ||
| Type: protein-coding gene | Cytoband: 7p14.3 | ||
| Entrez ID: 10842 | HGNC ID: HGNC:16973 | Ensembl Gene: ENSG00000106341 | OMIM ID: 604088 |
| Drug and gene relationship at DGIdb | |||
PPP1R17 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04730 | Long-term depression |
Expression of PPP1R17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R17 | 10842 | 231509_at | 0.0412 | 0.8953 | |
| GSE20347 | PPP1R17 | 10842 | 220231_at | -0.0545 | 0.4522 | |
| GSE23400 | PPP1R17 | 10842 | 220231_at | -0.0232 | 0.3824 | |
| GSE26886 | PPP1R17 | 10842 | 220231_at | 0.0419 | 0.7262 | |
| GSE29001 | PPP1R17 | 10842 | 220231_at | -0.1251 | 0.4807 | |
| GSE38129 | PPP1R17 | 10842 | 220231_at | -0.1359 | 0.0158 | |
| GSE45670 | PPP1R17 | 10842 | 220231_at | 0.4933 | 0.3948 | |
| GSE53622 | PPP1R17 | 10842 | 7276 | 0.1444 | 0.2322 | |
| GSE53624 | PPP1R17 | 10842 | 7276 | -0.2143 | 0.0088 | |
| GSE63941 | PPP1R17 | 10842 | 231509_at | 0.1569 | 0.4397 | |
| GSE77861 | PPP1R17 | 10842 | 231509_at | -0.1906 | 0.1482 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPP1R17 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PPP1R17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R17 | 10842 | 15 | 0 | 15 | |
| GSE20123 | PPP1R17 | 10842 | 15 | 0 | 15 | |
| GSE43470 | PPP1R17 | 10842 | 4 | 0 | 39 | |
| GSE46452 | PPP1R17 | 10842 | 11 | 1 | 47 | |
| GSE47630 | PPP1R17 | 10842 | 8 | 1 | 31 | |
| GSE54993 | PPP1R17 | 10842 | 0 | 6 | 64 | |
| GSE54994 | PPP1R17 | 10842 | 19 | 3 | 31 | |
| GSE60625 | PPP1R17 | 10842 | 0 | 0 | 11 | |
| GSE74703 | PPP1R17 | 10842 | 4 | 0 | 32 | |
| GSE74704 | PPP1R17 | 10842 | 9 | 0 | 11 | |
| TCGA | PPP1R17 | 10842 | 54 | 7 | 35 |
Total number of gains: 139; Total number of losses: 18; Total Number of normals: 331.
Somatic mutations of PPP1R17:
Generating mutation plots.
Highly correlated genes for PPP1R17:
Showing top 20/294 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R17 | NFE4 | 0.7093 | 3 | 0 | 3 |
| PPP1R17 | TECTA | 0.672172 | 4 | 0 | 3 |
| PPP1R17 | FN3K | 0.660049 | 4 | 0 | 3 |
| PPP1R17 | ATP4B | 0.655334 | 3 | 0 | 3 |
| PPP1R17 | KLF14 | 0.653842 | 3 | 0 | 3 |
| PPP1R17 | OLIG3 | 0.65024 | 4 | 0 | 3 |
| PPP1R17 | OPRK1 | 0.644628 | 5 | 0 | 5 |
| PPP1R17 | CA7 | 0.64401 | 6 | 0 | 5 |
| PPP1R17 | SLC1A6 | 0.636981 | 3 | 0 | 3 |
| PPP1R17 | UMOD | 0.635769 | 5 | 0 | 5 |
| PPP1R17 | PRODH2 | 0.630665 | 6 | 0 | 5 |
| PPP1R17 | PADI4 | 0.630426 | 3 | 0 | 3 |
| PPP1R17 | PDX1 | 0.626487 | 3 | 0 | 3 |
| PPP1R17 | NR6A1 | 0.621918 | 4 | 0 | 3 |
| PPP1R17 | TRPC5 | 0.613501 | 4 | 0 | 4 |
| PPP1R17 | SPRR4 | 0.608835 | 3 | 0 | 3 |
| PPP1R17 | P2RY4 | 0.608598 | 6 | 0 | 5 |
| PPP1R17 | GML | 0.60686 | 6 | 0 | 5 |
| PPP1R17 | DBH | 0.605971 | 5 | 0 | 3 |
| PPP1R17 | KIR2DS2 | 0.604135 | 7 | 0 | 5 |
For details and further investigation, click here
