| Full name: DAB2 interacting protein | Alias Symbol: AF9Q34|DIP1/2|KIAA1743|AIP1 | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 153090 | HGNC ID: HGNC:17294 | Ensembl Gene: ENSG00000136848 | OMIM ID: 609205 |
| Drug and gene relationship at DGIdb | |||
DAB2IP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04210 | Apoptosis | |
| hsa04668 | TNF signaling pathway |
Expression of DAB2IP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DAB2IP | 153090 | 225020_at | 0.5815 | 0.1406 | |
| GSE26886 | DAB2IP | 153090 | 235966_at | 0.1242 | 0.2957 | |
| GSE45670 | DAB2IP | 153090 | 225020_at | 0.1629 | 0.3086 | |
| GSE53622 | DAB2IP | 153090 | 123374 | -0.0271 | 0.7727 | |
| GSE53624 | DAB2IP | 153090 | 123374 | 0.3022 | 0.0008 | |
| GSE63941 | DAB2IP | 153090 | 225020_at | 0.9392 | 0.1400 | |
| GSE77861 | DAB2IP | 153090 | 235966_at | -0.0815 | 0.4561 | |
| GSE97050 | DAB2IP | 153090 | A_24_P149704 | -0.3186 | 0.4154 | |
| SRP007169 | DAB2IP | 153090 | RNAseq | 1.4622 | 0.0107 | |
| SRP008496 | DAB2IP | 153090 | RNAseq | 1.1500 | 0.0021 | |
| SRP064894 | DAB2IP | 153090 | RNAseq | 0.3152 | 0.0820 | |
| SRP133303 | DAB2IP | 153090 | RNAseq | 0.2212 | 0.4519 | |
| SRP159526 | DAB2IP | 153090 | RNAseq | -0.2230 | 0.4138 | |
| SRP193095 | DAB2IP | 153090 | RNAseq | 0.4341 | 0.0057 | |
| SRP219564 | DAB2IP | 153090 | RNAseq | -0.2315 | 0.5116 | |
| TCGA | DAB2IP | 153090 | RNAseq | -0.0629 | 0.3378 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DAB2IP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DAB2IP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DAB2IP | 153090 | 3 | 7 | 20 | |
| GSE20123 | DAB2IP | 153090 | 3 | 7 | 20 | |
| GSE43470 | DAB2IP | 153090 | 5 | 4 | 34 | |
| GSE46452 | DAB2IP | 153090 | 6 | 13 | 40 | |
| GSE47630 | DAB2IP | 153090 | 3 | 16 | 21 | |
| GSE54993 | DAB2IP | 153090 | 3 | 3 | 64 | |
| GSE54994 | DAB2IP | 153090 | 9 | 10 | 34 | |
| GSE60625 | DAB2IP | 153090 | 0 | 0 | 11 | |
| GSE74703 | DAB2IP | 153090 | 5 | 3 | 28 | |
| GSE74704 | DAB2IP | 153090 | 2 | 5 | 13 | |
| TCGA | DAB2IP | 153090 | 27 | 24 | 45 |
Total number of gains: 66; Total number of losses: 92; Total Number of normals: 330.
Somatic mutations of DAB2IP:
Generating mutation plots.
Highly correlated genes for DAB2IP:
Showing top 20/152 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DAB2IP | LIMD2 | 0.752853 | 3 | 0 | 3 |
| DAB2IP | TNPO2 | 0.741231 | 3 | 0 | 3 |
| DAB2IP | COMMD5 | 0.718678 | 3 | 0 | 3 |
| DAB2IP | USP36 | 0.715311 | 3 | 0 | 3 |
| DAB2IP | ZNF787 | 0.711483 | 3 | 0 | 3 |
| DAB2IP | PRR12 | 0.706844 | 3 | 0 | 3 |
| DAB2IP | FBXL6 | 0.696867 | 3 | 0 | 3 |
| DAB2IP | CARS2 | 0.695793 | 3 | 0 | 3 |
| DAB2IP | AVP | 0.688869 | 3 | 0 | 3 |
| DAB2IP | DGAT1 | 0.687302 | 3 | 0 | 3 |
| DAB2IP | NOXO1 | 0.678246 | 3 | 0 | 3 |
| DAB2IP | ACHE | 0.669403 | 3 | 0 | 3 |
| DAB2IP | DCUN1D2 | 0.666305 | 3 | 0 | 3 |
| DAB2IP | FAM124A | 0.663659 | 3 | 0 | 3 |
| DAB2IP | SEMA4G | 0.662389 | 3 | 0 | 3 |
| DAB2IP | SYMPK | 0.658857 | 3 | 0 | 3 |
| DAB2IP | CRTC2 | 0.654882 | 3 | 0 | 3 |
| DAB2IP | SLC25A28 | 0.65296 | 3 | 0 | 3 |
| DAB2IP | TP53I13 | 0.652522 | 3 | 0 | 3 |
| DAB2IP | TCEA2 | 0.651904 | 3 | 0 | 3 |
For details and further investigation, click here
