| Full name: EF-hand and coiled-coil domain containing 1 | Alias Symbol: FLJ12057 | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 79825 | HGNC ID: HGNC:25692 | Ensembl Gene: ENSG00000114654 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EFCC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFCC1 | 79825 | 220006_at | -0.2379 | 0.2593 | |
| GSE20347 | EFCC1 | 79825 | 220006_at | 0.1244 | 0.1786 | |
| GSE23400 | EFCC1 | 79825 | 220006_at | -0.2181 | 0.0000 | |
| GSE26886 | EFCC1 | 79825 | 220006_at | 0.2237 | 0.1800 | |
| GSE29001 | EFCC1 | 79825 | 220006_at | -0.0662 | 0.6644 | |
| GSE38129 | EFCC1 | 79825 | 220006_at | -0.2038 | 0.1134 | |
| GSE45670 | EFCC1 | 79825 | 220006_at | -0.1782 | 0.1234 | |
| GSE53622 | EFCC1 | 79825 | 5551 | -0.1939 | 0.0005 | |
| GSE53624 | EFCC1 | 79825 | 5551 | 0.0099 | 0.8850 | |
| GSE63941 | EFCC1 | 79825 | 220006_at | -0.3233 | 0.1255 | |
| GSE77861 | EFCC1 | 79825 | 220006_at | -0.0500 | 0.6633 | |
| SRP064894 | EFCC1 | 79825 | RNAseq | -0.6256 | 0.0733 | |
| SRP133303 | EFCC1 | 79825 | RNAseq | -1.2936 | 0.0002 | |
| SRP159526 | EFCC1 | 79825 | RNAseq | -0.8023 | 0.1207 | |
| SRP219564 | EFCC1 | 79825 | RNAseq | -0.1889 | 0.8571 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EFCC1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of EFCC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFCC1 | 79825 | 17 | 0 | 13 | |
| GSE20123 | EFCC1 | 79825 | 17 | 0 | 13 | |
| GSE43470 | EFCC1 | 79825 | 19 | 0 | 24 | |
| GSE46452 | EFCC1 | 79825 | 14 | 5 | 40 | |
| GSE47630 | EFCC1 | 79825 | 18 | 3 | 19 | |
| GSE54993 | EFCC1 | 79825 | 2 | 7 | 61 | |
| GSE54994 | EFCC1 | 79825 | 31 | 3 | 19 | |
| GSE60625 | EFCC1 | 79825 | 0 | 6 | 5 | |
| GSE74703 | EFCC1 | 79825 | 17 | 0 | 19 | |
| GSE74704 | EFCC1 | 79825 | 13 | 0 | 7 | |
| TCGA | EFCC1 | 79825 | 58 | 5 | 33 |
Total number of gains: 206; Total number of losses: 29; Total Number of normals: 253.
Somatic mutations of EFCC1:
Generating mutation plots.
Highly correlated genes for EFCC1:
Showing top 20/443 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFCC1 | KRT35 | 0.664448 | 3 | 0 | 3 |
| EFCC1 | SEMA4G | 0.66394 | 4 | 0 | 4 |
| EFCC1 | SYT13 | 0.661943 | 3 | 0 | 3 |
| EFCC1 | PZP | 0.655074 | 3 | 0 | 3 |
| EFCC1 | EPX | 0.654384 | 4 | 0 | 4 |
| EFCC1 | TNP1 | 0.649512 | 3 | 0 | 3 |
| EFCC1 | HTR3B | 0.647862 | 4 | 0 | 4 |
| EFCC1 | SYT5 | 0.646148 | 4 | 0 | 4 |
| EFCC1 | PSG1 | 0.645985 | 4 | 0 | 3 |
| EFCC1 | NPBWR2 | 0.644048 | 3 | 0 | 3 |
| EFCC1 | HNF4A | 0.643157 | 4 | 0 | 3 |
| EFCC1 | KIR3DL3 | 0.636285 | 5 | 0 | 4 |
| EFCC1 | CCDC30 | 0.633427 | 4 | 0 | 4 |
| EFCC1 | DENND1C | 0.632214 | 3 | 0 | 3 |
| EFCC1 | C1orf105 | 0.632032 | 4 | 0 | 4 |
| EFCC1 | ATP1A3 | 0.628925 | 4 | 0 | 4 |
| EFCC1 | DENND6B | 0.628797 | 5 | 0 | 4 |
| EFCC1 | ACVR2B-AS1 | 0.62763 | 4 | 0 | 4 |
| EFCC1 | NXPH3 | 0.627533 | 5 | 0 | 5 |
| EFCC1 | ATP2B2 | 0.626107 | 3 | 0 | 3 |
For details and further investigation, click here
