| Full name: glycoprotein 2 | Alias Symbol: ZAP75 | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 2813 | HGNC ID: HGNC:4441 | Ensembl Gene: ENSG00000169347 | OMIM ID: 602977 |
| Drug and gene relationship at DGIdb | |||
Expression of GP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GP2 | 2813 | 208473_s_at | -0.4994 | 0.3815 | |
| GSE20347 | GP2 | 2813 | 206681_x_at | -0.0451 | 0.6985 | |
| GSE23400 | GP2 | 2813 | 208473_s_at | -0.2891 | 0.0000 | |
| GSE26886 | GP2 | 2813 | 214324_at | 0.3419 | 0.0245 | |
| GSE29001 | GP2 | 2813 | 208473_s_at | 0.0719 | 0.6831 | |
| GSE38129 | GP2 | 2813 | 206681_x_at | -0.0615 | 0.6250 | |
| GSE45670 | GP2 | 2813 | 214324_at | -0.6911 | 0.0283 | |
| GSE53622 | GP2 | 2813 | 39819 | -2.9438 | 0.0000 | |
| GSE53624 | GP2 | 2813 | 39819 | -2.9656 | 0.0000 | |
| GSE63941 | GP2 | 2813 | 206681_x_at | 0.2933 | 0.0611 | |
| GSE77861 | GP2 | 2813 | 206681_x_at | -0.1170 | 0.3052 | |
| SRP133303 | GP2 | 2813 | RNAseq | -3.0178 | 0.0000 | |
| SRP159526 | GP2 | 2813 | RNAseq | 0.9164 | 0.3637 | |
| TCGA | GP2 | 2813 | RNAseq | -4.0088 | 0.0019 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by GP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GP2 | 2813 | 6 | 3 | 21 | |
| GSE20123 | GP2 | 2813 | 6 | 2 | 22 | |
| GSE43470 | GP2 | 2813 | 3 | 3 | 37 | |
| GSE46452 | GP2 | 2813 | 38 | 1 | 20 | |
| GSE47630 | GP2 | 2813 | 11 | 6 | 23 | |
| GSE54993 | GP2 | 2813 | 3 | 5 | 62 | |
| GSE54994 | GP2 | 2813 | 3 | 10 | 40 | |
| GSE60625 | GP2 | 2813 | 4 | 0 | 7 | |
| GSE74703 | GP2 | 2813 | 3 | 2 | 31 | |
| GSE74704 | GP2 | 2813 | 3 | 1 | 16 | |
| TCGA | GP2 | 2813 | 19 | 13 | 64 |
Total number of gains: 99; Total number of losses: 46; Total Number of normals: 343.
Somatic mutations of GP2:
Generating mutation plots.
Highly correlated genes for GP2:
Showing top 20/654 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GP2 | BPIFB1 | 0.802018 | 4 | 0 | 4 |
| GP2 | BPIFB2 | 0.746759 | 5 | 0 | 4 |
| GP2 | NXPE4 | 0.737688 | 9 | 0 | 8 |
| GP2 | EDA2R | 0.734616 | 4 | 0 | 4 |
| GP2 | ATG10 | 0.733795 | 4 | 0 | 4 |
| GP2 | MUC5B | 0.72299 | 7 | 0 | 7 |
| GP2 | AZGP1 | 0.720309 | 6 | 0 | 6 |
| GP2 | TFF3 | 0.719019 | 6 | 0 | 5 |
| GP2 | TFF1 | 0.718414 | 6 | 0 | 5 |
| GP2 | MS4A8 | 0.71788 | 3 | 0 | 3 |
| GP2 | GDF5 | 0.713509 | 4 | 0 | 4 |
| GP2 | LBP | 0.707677 | 4 | 0 | 4 |
| GP2 | C6orf58 | 0.70383 | 6 | 0 | 5 |
| GP2 | CCL16 | 0.703716 | 6 | 0 | 5 |
| GP2 | FOXN3-AS2 | 0.700069 | 5 | 0 | 5 |
| GP2 | TCL6 | 0.699976 | 5 | 0 | 5 |
| GP2 | CCL1 | 0.699455 | 4 | 0 | 4 |
| GP2 | KIR2DS3 | 0.69683 | 4 | 0 | 4 |
| GP2 | BTN1A1 | 0.690706 | 4 | 0 | 4 |
| GP2 | ZG16B | 0.687907 | 5 | 0 | 4 |
For details and further investigation, click here
