| Full name: neurexophilin 3 | Alias Symbol: NPH3 | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 11248 | HGNC ID: HGNC:8077 | Ensembl Gene: ENSG00000182575 | OMIM ID: 604636 |
| Drug and gene relationship at DGIdb | |||
Expression of NXPH3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NXPH3 | 11248 | 221991_at | -0.2562 | 0.4772 | |
| GSE20347 | NXPH3 | 11248 | 221991_at | 0.0318 | 0.7267 | |
| GSE23400 | NXPH3 | 11248 | 221991_at | -0.1330 | 0.0014 | |
| GSE26886 | NXPH3 | 11248 | 228210_at | 0.1774 | 0.1993 | |
| GSE29001 | NXPH3 | 11248 | 221991_at | -0.1556 | 0.3897 | |
| GSE38129 | NXPH3 | 11248 | 221991_at | -0.2544 | 0.0160 | |
| GSE45670 | NXPH3 | 11248 | 221991_at | -0.1783 | 0.0533 | |
| GSE53622 | NXPH3 | 11248 | 59311 | -0.9319 | 0.0000 | |
| GSE53624 | NXPH3 | 11248 | 59311 | -0.8758 | 0.0000 | |
| GSE63941 | NXPH3 | 11248 | 221991_at | 0.3835 | 0.0600 | |
| GSE77861 | NXPH3 | 11248 | 228210_at | -0.0068 | 0.9701 | |
| GSE97050 | NXPH3 | 11248 | A_24_P940086 | -0.2037 | 0.4587 | |
| SRP064894 | NXPH3 | 11248 | RNAseq | -0.0439 | 0.9288 | |
| SRP133303 | NXPH3 | 11248 | RNAseq | -1.3358 | 0.0132 | |
| SRP159526 | NXPH3 | 11248 | RNAseq | -0.3204 | 0.6172 | |
| SRP219564 | NXPH3 | 11248 | RNAseq | -0.1969 | 0.8401 | |
| TCGA | NXPH3 | 11248 | RNAseq | -0.8645 | 0.0019 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NXPH3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NXPH3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NXPH3 | 11248 | 6 | 2 | 22 | |
| GSE20123 | NXPH3 | 11248 | 6 | 2 | 22 | |
| GSE43470 | NXPH3 | 11248 | 3 | 2 | 38 | |
| GSE46452 | NXPH3 | 11248 | 32 | 0 | 27 | |
| GSE47630 | NXPH3 | 11248 | 9 | 0 | 31 | |
| GSE54993 | NXPH3 | 11248 | 2 | 4 | 64 | |
| GSE54994 | NXPH3 | 11248 | 10 | 5 | 38 | |
| GSE60625 | NXPH3 | 11248 | 4 | 0 | 7 | |
| GSE74703 | NXPH3 | 11248 | 3 | 2 | 31 | |
| GSE74704 | NXPH3 | 11248 | 4 | 1 | 15 | |
| TCGA | NXPH3 | 11248 | 27 | 7 | 62 |
Total number of gains: 106; Total number of losses: 25; Total Number of normals: 357.
Somatic mutations of NXPH3:
Generating mutation plots.
Highly correlated genes for NXPH3:
Showing top 20/739 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NXPH3 | PLB1 | 0.769373 | 3 | 0 | 3 |
| NXPH3 | C22orf39 | 0.764985 | 3 | 0 | 3 |
| NXPH3 | ZNF687 | 0.750102 | 3 | 0 | 3 |
| NXPH3 | PRR26 | 0.74084 | 3 | 0 | 3 |
| NXPH3 | MYH14 | 0.736368 | 3 | 0 | 3 |
| NXPH3 | WNT9A | 0.731994 | 3 | 0 | 3 |
| NXPH3 | FAM178B | 0.726721 | 3 | 0 | 3 |
| NXPH3 | TTBK1 | 0.726446 | 4 | 0 | 4 |
| NXPH3 | PRAMEF12 | 0.724584 | 6 | 0 | 6 |
| NXPH3 | TRPM3 | 0.721792 | 4 | 0 | 3 |
| NXPH3 | LIME1 | 0.721538 | 3 | 0 | 3 |
| NXPH3 | TNR | 0.720914 | 5 | 0 | 4 |
| NXPH3 | SLC22A12 | 0.720294 | 4 | 0 | 3 |
| NXPH3 | GRIK5 | 0.715623 | 9 | 0 | 8 |
| NXPH3 | NXNL1 | 0.713262 | 3 | 0 | 3 |
| NXPH3 | VIPR2 | 0.708574 | 9 | 0 | 8 |
| NXPH3 | LMAN1L | 0.703897 | 6 | 0 | 6 |
| NXPH3 | SYPL2 | 0.702208 | 4 | 0 | 3 |
| NXPH3 | SV2C | 0.700883 | 5 | 0 | 5 |
| NXPH3 | SVIL | 0.70063 | 4 | 0 | 4 |
For details and further investigation, click here
