| Full name: anti-Mullerian hormone receptor type 2 | Alias Symbol: MISR2|MISRII | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 269 | HGNC ID: HGNC:465 | Ensembl Gene: ENSG00000135409 | OMIM ID: 600956 |
| Drug and gene relationship at DGIdb | |||
AMHR2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04350 | TGF-beta signaling pathway |
Expression of AMHR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMHR2 | 269 | 206892_at | 0.0097 | 0.9822 | |
| GSE20347 | AMHR2 | 269 | 206892_at | -0.0391 | 0.7301 | |
| GSE23400 | AMHR2 | 269 | 206892_at | -0.2122 | 0.0000 | |
| GSE26886 | AMHR2 | 269 | 206892_at | 0.0132 | 0.9204 | |
| GSE29001 | AMHR2 | 269 | 206892_at | -0.3036 | 0.0671 | |
| GSE38129 | AMHR2 | 269 | 206892_at | -0.1926 | 0.0399 | |
| GSE45670 | AMHR2 | 269 | 206892_at | -0.0485 | 0.6123 | |
| GSE53622 | AMHR2 | 269 | 60704 | -0.0496 | 0.5243 | |
| GSE53624 | AMHR2 | 269 | 60704 | -0.1341 | 0.0570 | |
| GSE63941 | AMHR2 | 269 | 206892_at | 0.4050 | 0.0316 | |
| GSE77861 | AMHR2 | 269 | 206892_at | -0.1669 | 0.0983 | |
| GSE97050 | AMHR2 | 269 | A_24_P115990 | -0.1795 | 0.3620 | |
| TCGA | AMHR2 | 269 | RNAseq | -4.0443 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AMHR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMHR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMHR2 | 269 | 7 | 1 | 22 | |
| GSE20123 | AMHR2 | 269 | 7 | 1 | 22 | |
| GSE43470 | AMHR2 | 269 | 3 | 0 | 40 | |
| GSE46452 | AMHR2 | 269 | 7 | 1 | 51 | |
| GSE47630 | AMHR2 | 269 | 10 | 2 | 28 | |
| GSE54993 | AMHR2 | 269 | 0 | 5 | 65 | |
| GSE54994 | AMHR2 | 269 | 4 | 1 | 48 | |
| GSE60625 | AMHR2 | 269 | 0 | 0 | 11 | |
| GSE74703 | AMHR2 | 269 | 3 | 0 | 33 | |
| GSE74704 | AMHR2 | 269 | 5 | 1 | 14 | |
| TCGA | AMHR2 | 269 | 14 | 11 | 71 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of AMHR2:
Generating mutation plots.
Highly correlated genes for AMHR2:
Showing top 20/1407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMHR2 | C16orf82 | 0.790039 | 3 | 0 | 3 |
| AMHR2 | SPRED3 | 0.789028 | 3 | 0 | 3 |
| AMHR2 | SP7 | 0.788121 | 3 | 0 | 3 |
| AMHR2 | LRCH4 | 0.78346 | 3 | 0 | 3 |
| AMHR2 | SMOC1 | 0.779177 | 3 | 0 | 3 |
| AMHR2 | GFRA4 | 0.754343 | 7 | 0 | 7 |
| AMHR2 | INHBC | 0.752652 | 3 | 0 | 3 |
| AMHR2 | MAGEA8 | 0.750685 | 3 | 0 | 3 |
| AMHR2 | OR2C3 | 0.746308 | 3 | 0 | 3 |
| AMHR2 | CACFD1 | 0.744164 | 5 | 0 | 5 |
| AMHR2 | RALYL | 0.741038 | 4 | 0 | 4 |
| AMHR2 | TLR8 | 0.740892 | 3 | 0 | 3 |
| AMHR2 | ZNF687 | 0.73896 | 3 | 0 | 3 |
| AMHR2 | ASCL1 | 0.734328 | 4 | 0 | 4 |
| AMHR2 | ZNF491 | 0.730389 | 3 | 0 | 3 |
| AMHR2 | S100A5 | 0.727746 | 6 | 0 | 6 |
| AMHR2 | HPX | 0.725697 | 9 | 0 | 9 |
| AMHR2 | ADM2 | 0.723221 | 9 | 0 | 9 |
| AMHR2 | PGC | 0.717062 | 4 | 0 | 3 |
| AMHR2 | TSGA13 | 0.716875 | 4 | 0 | 3 |
For details and further investigation, click here
