| Full name: proline rich protein BstNI subfamily 1 (gene/pseudogene) | Alias Symbol: PM|PMF|PMS|PRB1M|PRB1L | ||
| Type: protein-coding gene | Cytoband: 12p13.2 | ||
| Entrez ID: 5542 | HGNC ID: HGNC:9337 | Ensembl Gene: ENSG00000251655 | OMIM ID: 180989 |
| Drug and gene relationship at DGIdb | |||
Expression of PRB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRB1 | 5542 | 211531_x_at | -0.0642 | 0.7860 | |
| GSE20347 | PRB1 | 5542 | 211531_x_at | -0.0644 | 0.5109 | |
| GSE23400 | PRB1 | 5542 | 211531_x_at | -0.2219 | 0.0000 | |
| GSE26886 | PRB1 | 5542 | 211531_x_at | -0.2763 | 0.3187 | |
| GSE29001 | PRB1 | 5542 | 211531_x_at | -0.2742 | 0.1463 | |
| GSE38129 | PRB1 | 5542 | 210597_x_at | -0.0786 | 0.4312 | |
| GSE45670 | PRB1 | 5542 | 211531_x_at | 0.0968 | 0.4002 | |
| GSE53622 | PRB1 | 5542 | 15693 | -1.1812 | 0.0000 | |
| GSE53624 | PRB1 | 5542 | 15693 | -1.7418 | 0.0000 | |
| GSE63941 | PRB1 | 5542 | 211531_x_at | 0.9019 | 0.0001 | |
| GSE77861 | PRB1 | 5542 | 211531_x_at | -0.1962 | 0.1192 | |
| GSE97050 | PRB1 | 5542 | A_33_P3258593 | -1.2758 | 0.2503 | |
| TCGA | PRB1 | 5542 | RNAseq | 0.8441 | 0.6464 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PRB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRB1 | 5542 | 6 | 2 | 22 | |
| GSE20123 | PRB1 | 5542 | 6 | 2 | 22 | |
| GSE43470 | PRB1 | 5542 | 10 | 3 | 30 | |
| GSE46452 | PRB1 | 5542 | 10 | 1 | 48 | |
| GSE47630 | PRB1 | 5542 | 13 | 2 | 25 | |
| GSE54993 | PRB1 | 5542 | 1 | 9 | 60 | |
| GSE54994 | PRB1 | 5542 | 10 | 2 | 41 | |
| GSE60625 | PRB1 | 5542 | 0 | 1 | 10 | |
| GSE74703 | PRB1 | 5542 | 9 | 2 | 25 | |
| GSE74704 | PRB1 | 5542 | 4 | 1 | 15 | |
| TCGA | PRB1 | 5542 | 39 | 7 | 50 |
Total number of gains: 108; Total number of losses: 32; Total Number of normals: 348.
Somatic mutations of PRB1:
Generating mutation plots.
Highly correlated genes for PRB1:
Showing top 20/1289 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRB1 | PRH2 | 0.821011 | 3 | 0 | 3 |
| PRB1 | LINC01119 | 0.779038 | 3 | 0 | 3 |
| PRB1 | PRB4 | 0.752781 | 12 | 0 | 11 |
| PRB1 | UCN3 | 0.741278 | 3 | 0 | 3 |
| PRB1 | C4orf17 | 0.72642 | 3 | 0 | 3 |
| PRB1 | DEFB118 | 0.712041 | 5 | 0 | 5 |
| PRB1 | LINC00347 | 0.700985 | 4 | 0 | 4 |
| PRB1 | EDA2R | 0.700264 | 6 | 0 | 6 |
| PRB1 | GAB4 | 0.695671 | 3 | 0 | 3 |
| PRB1 | KLK4 | 0.694652 | 3 | 0 | 3 |
| PRB1 | RGR | 0.692543 | 5 | 0 | 4 |
| PRB1 | MIR4755 | 0.689984 | 5 | 0 | 4 |
| PRB1 | SHC2 | 0.688909 | 3 | 0 | 3 |
| PRB1 | NUCB1 | 0.68876 | 3 | 0 | 3 |
| PRB1 | GFRA4 | 0.687616 | 6 | 0 | 5 |
| PRB1 | LRRC26 | 0.686509 | 3 | 0 | 3 |
| PRB1 | VIPR2 | 0.684989 | 7 | 0 | 7 |
| PRB1 | ART1 | 0.681359 | 6 | 0 | 6 |
| PRB1 | PACS2 | 0.681328 | 3 | 0 | 3 |
| PRB1 | DCXR | 0.681189 | 3 | 0 | 3 |
For details and further investigation, click here
