| Full name: cytokine receptor like factor 2 | Alias Symbol: CRL2|TSLPR | ||
| Type: protein-coding gene | Cytoband: Xp22.3 and Yp11.3 | ||
| Entrez ID: 64109 | HGNC ID: HGNC:14281 | Ensembl Gene: ENSG00000205755 | OMIM ID: 300357|400023 |
| Drug and gene relationship at DGIdb | |||
CRLF2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway |
Expression of CRLF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRLF2 | 64109 | 208303_s_at | -0.1049 | 0.6867 | |
| GSE20347 | CRLF2 | 64109 | 208303_s_at | -0.0473 | 0.5744 | |
| GSE23400 | CRLF2 | 64109 | 208303_s_at | -0.2752 | 0.0000 | |
| GSE26886 | CRLF2 | 64109 | 208303_s_at | -0.1271 | 0.3203 | |
| GSE29001 | CRLF2 | 64109 | 208303_s_at | -0.2964 | 0.0422 | |
| GSE38129 | CRLF2 | 64109 | 208303_s_at | -0.1680 | 0.0401 | |
| GSE45670 | CRLF2 | 64109 | 208303_s_at | 0.0262 | 0.8164 | |
| GSE63941 | CRLF2 | 64109 | 208303_s_at | 0.0468 | 0.8073 | |
| GSE77861 | CRLF2 | 64109 | 208303_s_at | -0.1372 | 0.1513 | |
| GSE97050 | CRLF2 | 64109 | A_33_P3298139 | 0.3614 | 0.1550 | |
| SRP133303 | CRLF2 | 64109 | RNAseq | -0.7405 | 0.0080 | |
| TCGA | CRLF2 | 64109 | RNAseq | -1.5331 | 0.0523 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRLF2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CRLF2:
No record found for this gene.
Somatic mutations of CRLF2:
Generating mutation plots.
Highly correlated genes for CRLF2:
Showing top 20/833 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRLF2 | RUNX1T1 | 0.700283 | 3 | 0 | 3 |
| CRLF2 | ENPP3 | 0.700093 | 3 | 0 | 3 |
| CRLF2 | GRIP2 | 0.695496 | 5 | 0 | 5 |
| CRLF2 | STXBP6 | 0.694283 | 3 | 0 | 3 |
| CRLF2 | ASMT | 0.678257 | 4 | 0 | 3 |
| CRLF2 | SNX32 | 0.674802 | 3 | 0 | 3 |
| CRLF2 | SH2D1A | 0.671849 | 3 | 0 | 3 |
| CRLF2 | RGR | 0.666874 | 4 | 0 | 3 |
| CRLF2 | SPX | 0.666182 | 5 | 0 | 4 |
| CRLF2 | HTR3C | 0.665416 | 3 | 0 | 3 |
| CRLF2 | ACVR2B-AS1 | 0.661933 | 5 | 0 | 5 |
| CRLF2 | GPR31 | 0.660047 | 6 | 0 | 6 |
| CRLF2 | PIWIL2 | 0.65957 | 5 | 0 | 4 |
| CRLF2 | ZNF582-AS1 | 0.659567 | 3 | 0 | 3 |
| CRLF2 | GDF2 | 0.658116 | 3 | 0 | 3 |
| CRLF2 | KLHL35 | 0.656561 | 4 | 0 | 4 |
| CRLF2 | PRODH2 | 0.656502 | 6 | 0 | 6 |
| CRLF2 | KLHL4 | 0.654448 | 4 | 0 | 4 |
| CRLF2 | SSTR4 | 0.653898 | 5 | 0 | 5 |
| CRLF2 | IL18BP | 0.651985 | 5 | 0 | 4 |
For details and further investigation, click here
