ST7

 

Full name: suppression of tumorigenicity 7 Alias Symbol: TSG7|SEN4|ETS7q|HELG|RAY1|FAM4A
Type: protein-coding gene Cytoband: 7q31.2
Entrez ID: 7982 HGNC ID: HGNC:11351 Ensembl Gene: ENSG00000004866 OMIM ID: 600833
Drug and gene relationship at DGIdb

 

Expression of ST7:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 ST7 7982 53162 0.4229 0.0000
GSE53624 ST7 7982 53162 0.2082 0.0211
GSE97050 ST7 7982 A_23_P215735 0.2233 0.4948
SRP007169 ST7 7982 RNAseq 0.4908 0.2162
SRP008496 ST7 7982 RNAseq 0.2532 0.3201
SRP064894 ST7 7982 RNAseq 0.4511 0.0104
SRP133303 ST7 7982 RNAseq 0.5065 0.0000
SRP159526 ST7 7982 RNAseq 0.3951 0.0739
SRP193095 ST7 7982 RNAseq 0.1762 0.1296
SRP219564 ST7 7982 RNAseq 0.3880 0.2591
TCGA ST7 7982 RNAseq -0.1136 0.0405

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ST7 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ST7:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ST7 7982 9 2 19
GSE20123 ST7 7982 10 2 18
GSE43470 ST7 7982 3 2 38
GSE46452 ST7 7982 8 1 50
GSE47630 ST7 7982 7 4 29
GSE54993 ST7 7982 2 7 61
GSE54994 ST7 7982 12 5 36
GSE60625 ST7 7982 0 0 11
GSE74703 ST7 7982 3 2 31
GSE74704 ST7 7982 7 2 11
TCGA ST7 7982 33 17 46

Total number of gains: 94; Total number of losses: 44; Total Number of normals: 350.  

 

Somatic mutations of ST7:

 

Generating mutation plots.

 

Highly correlated genes for ST7:

 

Showing all 10 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ST7BFAR0.67372303
ST7TRIM270.62866303
ST7CASP60.628398303
ST7SH3BP40.597933303
ST7TMEM90.59642303
ST7STIM20.591939303
ST7CSGALNACT20.583366303
ST7POLE40.537713303
ST7FBXO220.526488303
ST7POT10.512153403

For details and further investigation, click here