| Full name: F-box protein 22 | Alias Symbol: FBX22|FISTC1 | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 26263 | HGNC ID: HGNC:13593 | Ensembl Gene: ENSG00000167196 | OMIM ID: 609096 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO22 | 26263 | 225736_at | 0.2330 | 0.7304 | |
| GSE20347 | FBXO22 | 26263 | 219638_at | -0.0420 | 0.6967 | |
| GSE23400 | FBXO22 | 26263 | 219638_at | -0.0025 | 0.9245 | |
| GSE26886 | FBXO22 | 26263 | 225736_at | -0.0761 | 0.6824 | |
| GSE29001 | FBXO22 | 26263 | 219638_at | -0.1840 | 0.4625 | |
| GSE38129 | FBXO22 | 26263 | 219638_at | 0.0020 | 0.9878 | |
| GSE45670 | FBXO22 | 26263 | 225736_at | 0.6352 | 0.0014 | |
| GSE53622 | FBXO22 | 26263 | 68771 | 0.5329 | 0.0000 | |
| GSE53624 | FBXO22 | 26263 | 68771 | 0.5277 | 0.0000 | |
| GSE63941 | FBXO22 | 26263 | 225736_at | 0.5087 | 0.2764 | |
| GSE77861 | FBXO22 | 26263 | 225736_at | 0.0980 | 0.7005 | |
| GSE97050 | FBXO22 | 26263 | A_23_P65870 | 0.3990 | 0.1899 | |
| SRP007169 | FBXO22 | 26263 | RNAseq | 0.2938 | 0.4146 | |
| SRP008496 | FBXO22 | 26263 | RNAseq | 0.0781 | 0.7428 | |
| SRP064894 | FBXO22 | 26263 | RNAseq | 0.0949 | 0.5998 | |
| SRP133303 | FBXO22 | 26263 | RNAseq | 0.3921 | 0.0060 | |
| SRP159526 | FBXO22 | 26263 | RNAseq | 0.4140 | 0.1120 | |
| SRP193095 | FBXO22 | 26263 | RNAseq | 0.1219 | 0.0896 | |
| SRP219564 | FBXO22 | 26263 | RNAseq | -0.0802 | 0.7934 | |
| TCGA | FBXO22 | 26263 | RNAseq | 0.1092 | 0.0616 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXO22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO22 | 26263 | 8 | 1 | 21 | |
| GSE20123 | FBXO22 | 26263 | 8 | 1 | 21 | |
| GSE43470 | FBXO22 | 26263 | 4 | 6 | 33 | |
| GSE46452 | FBXO22 | 26263 | 3 | 7 | 49 | |
| GSE47630 | FBXO22 | 26263 | 8 | 10 | 22 | |
| GSE54993 | FBXO22 | 26263 | 5 | 6 | 59 | |
| GSE54994 | FBXO22 | 26263 | 5 | 6 | 42 | |
| GSE60625 | FBXO22 | 26263 | 4 | 0 | 7 | |
| GSE74703 | FBXO22 | 26263 | 4 | 3 | 29 | |
| GSE74704 | FBXO22 | 26263 | 4 | 1 | 15 | |
| TCGA | FBXO22 | 26263 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 56; Total Number of normals: 365.
Somatic mutations of FBXO22:
Generating mutation plots.
Highly correlated genes for FBXO22:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO22 | SMUG1 | 0.711832 | 3 | 0 | 3 |
| FBXO22 | UBE2S | 0.694361 | 3 | 0 | 3 |
| FBXO22 | RAPGEF5 | 0.68878 | 4 | 0 | 3 |
| FBXO22 | SF3A3 | 0.687378 | 3 | 0 | 3 |
| FBXO22 | SFT2D1 | 0.680485 | 5 | 0 | 4 |
| FBXO22 | MRPL28 | 0.674707 | 4 | 0 | 4 |
| FBXO22 | KNSTRN | 0.674659 | 6 | 0 | 6 |
| FBXO22 | MFSD10 | 0.672505 | 3 | 0 | 3 |
| FBXO22 | MRPS17 | 0.670342 | 4 | 0 | 3 |
| FBXO22 | GALK2 | 0.668417 | 4 | 0 | 3 |
| FBXO22 | SH2D5 | 0.667882 | 4 | 0 | 4 |
| FBXO22 | POC1A | 0.661999 | 5 | 0 | 4 |
| FBXO22 | PDCD11 | 0.659959 | 5 | 0 | 3 |
| FBXO22 | APLN | 0.659659 | 4 | 0 | 3 |
| FBXO22 | ETAA1 | 0.657 | 5 | 0 | 4 |
| FBXO22 | DHX9 | 0.649522 | 4 | 0 | 3 |
| FBXO22 | CDSN | 0.646988 | 3 | 0 | 3 |
| FBXO22 | UBL7-AS1 | 0.646468 | 5 | 0 | 5 |
| FBXO22 | FPR1 | 0.641751 | 3 | 0 | 3 |
| FBXO22 | HAUS8 | 0.641106 | 5 | 0 | 3 |
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