| Full name: bifunctional apoptosis regulator | Alias Symbol: BAR|RNF47 | ||
| Type: protein-coding gene | Cytoband: 16p13.12 | ||
| Entrez ID: 51283 | HGNC ID: HGNC:17613 | Ensembl Gene: ENSG00000103429 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of BFAR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BFAR | 51283 | 218056_at | 0.4559 | 0.2492 | |
| GSE20347 | BFAR | 51283 | 218056_at | 0.6682 | 0.0001 | |
| GSE23400 | BFAR | 51283 | 218056_at | 0.5372 | 0.0000 | |
| GSE26886 | BFAR | 51283 | 218056_at | 0.9335 | 0.0000 | |
| GSE29001 | BFAR | 51283 | 218056_at | 0.7859 | 0.0063 | |
| GSE38129 | BFAR | 51283 | 218056_at | 0.5874 | 0.0000 | |
| GSE45670 | BFAR | 51283 | 218056_at | 0.4109 | 0.0242 | |
| GSE53622 | BFAR | 51283 | 11500 | 0.7810 | 0.0000 | |
| GSE53624 | BFAR | 51283 | 11500 | 0.8521 | 0.0000 | |
| GSE63941 | BFAR | 51283 | 218056_at | -0.3978 | 0.3091 | |
| GSE77861 | BFAR | 51283 | 218056_at | 0.7489 | 0.0186 | |
| GSE97050 | BFAR | 51283 | A_23_P65963 | 0.2328 | 0.3783 | |
| SRP007169 | BFAR | 51283 | RNAseq | 1.5372 | 0.0000 | |
| SRP008496 | BFAR | 51283 | RNAseq | 1.2506 | 0.0000 | |
| SRP064894 | BFAR | 51283 | RNAseq | 0.5207 | 0.0016 | |
| SRP133303 | BFAR | 51283 | RNAseq | 0.7750 | 0.0000 | |
| SRP159526 | BFAR | 51283 | RNAseq | 0.6930 | 0.0213 | |
| SRP193095 | BFAR | 51283 | RNAseq | 0.4010 | 0.0216 | |
| SRP219564 | BFAR | 51283 | RNAseq | 0.5196 | 0.0403 | |
| TCGA | BFAR | 51283 | RNAseq | 0.0484 | 0.3220 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by BFAR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BFAR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BFAR | 51283 | 5 | 4 | 21 | |
| GSE20123 | BFAR | 51283 | 5 | 3 | 22 | |
| GSE43470 | BFAR | 51283 | 3 | 3 | 37 | |
| GSE46452 | BFAR | 51283 | 38 | 1 | 20 | |
| GSE47630 | BFAR | 51283 | 13 | 7 | 20 | |
| GSE54993 | BFAR | 51283 | 3 | 5 | 62 | |
| GSE54994 | BFAR | 51283 | 4 | 11 | 38 | |
| GSE60625 | BFAR | 51283 | 4 | 1 | 6 | |
| GSE74703 | BFAR | 51283 | 3 | 2 | 31 | |
| GSE74704 | BFAR | 51283 | 2 | 1 | 17 | |
| TCGA | BFAR | 51283 | 20 | 12 | 64 |
Total number of gains: 100; Total number of losses: 50; Total Number of normals: 338.
Somatic mutations of BFAR:
Generating mutation plots.
Highly correlated genes for BFAR:
Showing top 20/1107 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BFAR | C18orf54 | 0.712242 | 5 | 0 | 5 |
| BFAR | ARHGAP21 | 0.6949 | 4 | 0 | 4 |
| BFAR | ACTL6A | 0.685917 | 10 | 0 | 10 |
| BFAR | CMSS1 | 0.684531 | 6 | 0 | 6 |
| BFAR | FNDC3B | 0.681289 | 11 | 0 | 9 |
| BFAR | PPT1 | 0.681214 | 10 | 0 | 9 |
| BFAR | GFM1 | 0.679055 | 6 | 0 | 6 |
| BFAR | MAD2L2 | 0.678972 | 5 | 0 | 5 |
| BFAR | PRPS1 | 0.67874 | 11 | 0 | 10 |
| BFAR | TRAF7 | 0.677026 | 4 | 0 | 4 |
| BFAR | UBTD2 | 0.675124 | 4 | 0 | 4 |
| BFAR | COLGALT1 | 0.674169 | 10 | 0 | 10 |
| BFAR | ST7 | 0.67372 | 3 | 0 | 3 |
| BFAR | ZDHHC16 | 0.672988 | 5 | 0 | 5 |
| BFAR | PDIA5 | 0.672842 | 3 | 0 | 3 |
| BFAR | LSM10 | 0.672459 | 5 | 0 | 5 |
| BFAR | C5orf15 | 0.67123 | 8 | 0 | 8 |
| BFAR | INO80E | 0.671165 | 3 | 0 | 3 |
| BFAR | KIF3B | 0.671012 | 11 | 0 | 10 |
| BFAR | PGP | 0.670361 | 4 | 0 | 4 |
For details and further investigation, click here
