STIM2

 

Full name: stromal interaction molecule 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 4p15.2
Entrez ID: 57620 HGNC ID: HGNC:19205 Ensembl Gene: ENSG00000109689 OMIM ID: 610841
Drug and gene relationship at DGIdb

 

STIM2 involved pathways:

KEGG pathway Description View
hsa04020Calcium signaling pathway

 

Expression of STIM2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STIM2 57620 225246_at 1.0877 0.0498
GSE26886 STIM2 57620 234140_s_at 0.7970 0.0001
GSE45670 STIM2 57620 234140_s_at 0.3927 0.1243
GSE53622 STIM2 57620 99598 0.7614 0.0000
GSE53624 STIM2 57620 99598 0.7648 0.0000
GSE63941 STIM2 57620 225246_at -1.4555 0.0141
GSE77861 STIM2 57620 234140_s_at 0.8528 0.0089
GSE97050 STIM2 57620 A_23_P81048 0.2716 0.3054
SRP007169 STIM2 57620 RNAseq 1.4902 0.0004
SRP008496 STIM2 57620 RNAseq 1.7002 0.0000
SRP064894 STIM2 57620 RNAseq 0.7261 0.0000
SRP133303 STIM2 57620 RNAseq 0.2889 0.0140
SRP159526 STIM2 57620 RNAseq 0.7412 0.0190
SRP193095 STIM2 57620 RNAseq 0.4365 0.0193
SRP219564 STIM2 57620 RNAseq 1.0930 0.0000
TCGA STIM2 57620 RNAseq 0.0950 0.1056

Upregulated datasets: 4; Downregulated datasets: 1.  

 

Survival by STIM2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of STIM2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STIM2 57620 0 18 12
GSE20123 STIM2 57620 0 16 14
GSE43470 STIM2 57620 0 13 30
GSE46452 STIM2 57620 1 36 22
GSE47630 STIM2 57620 1 19 20
GSE54993 STIM2 57620 9 0 61
GSE54994 STIM2 57620 5 11 37
GSE60625 STIM2 57620 0 0 11
GSE74703 STIM2 57620 0 11 25
GSE74704 STIM2 57620 0 10 10
TCGA STIM2 57620 11 47 38

Total number of gains: 27; Total number of losses: 181; Total Number of normals: 280.  

 

Somatic mutations of STIM2:

 

Generating mutation plots.

 

Highly correlated genes for STIM2:

 

Showing top 20/902 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STIM2TTC130.747178404
STIM2MTERF30.735532404
STIM2PDE7A0.732237505
STIM2DVL20.726579403
STIM2TRIO0.719169504
STIM2LRP120.717295606
STIM2CCDC860.712795303
STIM2TNC0.699291404
STIM2LPCAT10.690155606
STIM2ATG2A0.682932303
STIM2SLC52A10.682254303
STIM2SERPINH10.681809605
STIM2RBM410.678883303
STIM2NCAPG0.675441403
STIM2IFNGR10.674573606
STIM2CERS20.673426404
STIM2PRR5L0.672788605
STIM2AP2B10.671663504
STIM2BOD10.669861404
STIM2RNF2170.669728403

For details and further investigation, click here