| Full name: tripartite motif containing 27 | Alias Symbol: RNF76 | ||
| Type: protein-coding gene | Cytoband: 6p22.1 | ||
| Entrez ID: 5987 | HGNC ID: HGNC:9975 | Ensembl Gene: ENSG00000204713 | OMIM ID: 602165 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM27 | 5987 | 212118_at | 0.7146 | 0.2743 | |
| GSE20347 | TRIM27 | 5987 | 212116_at | 0.6944 | 0.0001 | |
| GSE23400 | TRIM27 | 5987 | 212118_at | 0.4490 | 0.0000 | |
| GSE26886 | TRIM27 | 5987 | 212116_at | 0.9695 | 0.0004 | |
| GSE29001 | TRIM27 | 5987 | 212118_at | 0.5161 | 0.0294 | |
| GSE38129 | TRIM27 | 5987 | 212116_at | 0.7268 | 0.0000 | |
| GSE45670 | TRIM27 | 5987 | 212118_at | 0.0863 | 0.6880 | |
| GSE53622 | TRIM27 | 5987 | 103434 | 0.5901 | 0.0000 | |
| GSE53624 | TRIM27 | 5987 | 103434 | 0.8083 | 0.0000 | |
| GSE63941 | TRIM27 | 5987 | 212116_at | -0.0830 | 0.8282 | |
| GSE77861 | TRIM27 | 5987 | 212118_at | 0.1010 | 0.7097 | |
| GSE97050 | TRIM27 | 5987 | A_32_P137035 | 0.5624 | 0.1533 | |
| SRP007169 | TRIM27 | 5987 | RNAseq | 0.5993 | 0.1350 | |
| SRP008496 | TRIM27 | 5987 | RNAseq | 0.6823 | 0.0087 | |
| SRP064894 | TRIM27 | 5987 | RNAseq | 0.6591 | 0.0000 | |
| SRP133303 | TRIM27 | 5987 | RNAseq | 0.4609 | 0.0005 | |
| SRP159526 | TRIM27 | 5987 | RNAseq | 0.5223 | 0.0064 | |
| SRP193095 | TRIM27 | 5987 | RNAseq | 0.3027 | 0.0174 | |
| SRP219564 | TRIM27 | 5987 | RNAseq | 0.8610 | 0.0047 | |
| TCGA | TRIM27 | 5987 | RNAseq | -0.0332 | 0.4881 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRIM27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM27 | 5987 | 3 | 2 | 25 | |
| GSE20123 | TRIM27 | 5987 | 3 | 2 | 25 | |
| GSE43470 | TRIM27 | 5987 | 5 | 0 | 38 | |
| GSE46452 | TRIM27 | 5987 | 1 | 10 | 48 | |
| GSE47630 | TRIM27 | 5987 | 7 | 4 | 29 | |
| GSE54993 | TRIM27 | 5987 | 2 | 1 | 67 | |
| GSE54994 | TRIM27 | 5987 | 11 | 4 | 38 | |
| GSE60625 | TRIM27 | 5987 | 0 | 1 | 10 | |
| GSE74703 | TRIM27 | 5987 | 5 | 0 | 31 | |
| GSE74704 | TRIM27 | 5987 | 0 | 1 | 19 | |
| TCGA | TRIM27 | 5987 | 16 | 19 | 61 |
Total number of gains: 53; Total number of losses: 44; Total Number of normals: 391.
Somatic mutations of TRIM27:
Generating mutation plots.
Highly correlated genes for TRIM27:
Showing top 20/1085 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM27 | UQCC2 | 0.725229 | 3 | 0 | 3 |
| TRIM27 | SBK1 | 0.716434 | 3 | 0 | 3 |
| TRIM27 | PTGES3 | 0.714338 | 4 | 0 | 4 |
| TRIM27 | SETD1A | 0.71187 | 3 | 0 | 3 |
| TRIM27 | BYSL | 0.708335 | 10 | 0 | 10 |
| TRIM27 | CHTF18 | 0.684471 | 3 | 0 | 3 |
| TRIM27 | TXNDC12 | 0.683938 | 5 | 0 | 5 |
| TRIM27 | YDJC | 0.680803 | 5 | 0 | 5 |
| TRIM27 | SH3BP4 | 0.67816 | 8 | 0 | 8 |
| TRIM27 | SOX4 | 0.6754 | 9 | 0 | 8 |
| TRIM27 | DNA2 | 0.672149 | 9 | 0 | 9 |
| TRIM27 | METTL23 | 0.67145 | 5 | 0 | 4 |
| TRIM27 | ABCF1 | 0.669017 | 10 | 0 | 10 |
| TRIM27 | SPC24 | 0.668196 | 5 | 0 | 5 |
| TRIM27 | DPY19L1 | 0.664454 | 9 | 0 | 9 |
| TRIM27 | GEMIN4 | 0.662533 | 5 | 0 | 5 |
| TRIM27 | ASB6 | 0.661693 | 4 | 0 | 4 |
| TRIM27 | MEA1 | 0.659962 | 7 | 0 | 7 |
| TRIM27 | MCM3 | 0.657353 | 8 | 0 | 8 |
| TRIM27 | SLC16A1 | 0.654039 | 6 | 0 | 6 |
For details and further investigation, click here
