| Full name: synaptotagmin 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 148281 | HGNC ID: HGNC:18638 | Ensembl Gene: ENSG00000134207 | OMIM ID: 607718 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT6 | 148281 | 244227_at | -0.0084 | 0.9798 | |
| GSE26886 | SYT6 | 148281 | 244227_at | -0.1057 | 0.1928 | |
| GSE45670 | SYT6 | 148281 | 244227_at | -0.0586 | 0.5966 | |
| GSE53622 | SYT6 | 148281 | 39357 | 0.3036 | 0.3579 | |
| GSE53624 | SYT6 | 148281 | 1331 | -0.0465 | 0.7046 | |
| GSE63941 | SYT6 | 148281 | 244227_at | 0.0320 | 0.8929 | |
| GSE77861 | SYT6 | 148281 | 244227_at | -0.1840 | 0.0584 | |
| TCGA | SYT6 | 148281 | RNAseq | -1.2476 | 0.0283 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SYT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT6 | 148281 | 0 | 9 | 21 | |
| GSE20123 | SYT6 | 148281 | 0 | 9 | 21 | |
| GSE43470 | SYT6 | 148281 | 0 | 8 | 35 | |
| GSE46452 | SYT6 | 148281 | 2 | 1 | 56 | |
| GSE47630 | SYT6 | 148281 | 9 | 5 | 26 | |
| GSE54993 | SYT6 | 148281 | 0 | 1 | 69 | |
| GSE54994 | SYT6 | 148281 | 7 | 3 | 43 | |
| GSE60625 | SYT6 | 148281 | 0 | 0 | 11 | |
| GSE74703 | SYT6 | 148281 | 0 | 7 | 29 | |
| GSE74704 | SYT6 | 148281 | 0 | 5 | 15 | |
| TCGA | SYT6 | 148281 | 11 | 30 | 55 |
Total number of gains: 29; Total number of losses: 78; Total Number of normals: 381.
Somatic mutations of SYT6:
Generating mutation plots.
Highly correlated genes for SYT6:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT6 | DACT3-AS1 | 0.699397 | 3 | 0 | 3 |
| SYT6 | NRXN2 | 0.6743 | 3 | 0 | 3 |
| SYT6 | DLGAP2 | 0.669191 | 4 | 0 | 4 |
| SYT6 | FAM171A2 | 0.661988 | 3 | 0 | 3 |
| SYT6 | HAAO | 0.658809 | 3 | 0 | 3 |
| SYT6 | SLC17A4 | 0.651379 | 3 | 0 | 3 |
| SYT6 | CTIF | 0.649479 | 3 | 0 | 3 |
| SYT6 | LINC01007 | 0.647465 | 3 | 0 | 3 |
| SYT6 | KDM8 | 0.643924 | 3 | 0 | 3 |
| SYT6 | OVCH1-AS1 | 0.642873 | 3 | 0 | 3 |
| SYT6 | MIR210HG | 0.639812 | 3 | 0 | 3 |
| SYT6 | ST3GAL3 | 0.63467 | 3 | 0 | 3 |
| SYT6 | TEX35 | 0.634374 | 3 | 0 | 3 |
| SYT6 | MYO18B | 0.632903 | 3 | 0 | 3 |
| SYT6 | C20orf173 | 0.621739 | 3 | 0 | 3 |
| SYT6 | LINC00868 | 0.61975 | 3 | 0 | 3 |
| SYT6 | RASL10B | 0.619448 | 3 | 0 | 3 |
| SYT6 | FAM47C | 0.618959 | 3 | 0 | 3 |
| SYT6 | FUT3 | 0.612253 | 3 | 0 | 3 |
| SYT6 | ELF3 | 0.610256 | 3 | 0 | 3 |
For details and further investigation, click here
