| Full name: myosin XVIIIB | Alias Symbol: BK125H2.1 | ||
| Type: protein-coding gene | Cytoband: 22q12.1 | ||
| Entrez ID: 84700 | HGNC ID: HGNC:18150 | Ensembl Gene: ENSG00000133454 | OMIM ID: 607295 |
| Drug and gene relationship at DGIdb | |||
Expression of MYO18B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYO18B | 84700 | 1554579_a_at | -0.1103 | 0.6858 | |
| GSE26886 | MYO18B | 84700 | 1554579_a_at | -0.0841 | 0.3501 | |
| GSE45670 | MYO18B | 84700 | 1554579_a_at | -0.0367 | 0.7562 | |
| GSE53622 | MYO18B | 84700 | 111035 | -0.1556 | 0.2807 | |
| GSE53624 | MYO18B | 84700 | 137087 | -0.2406 | 0.0504 | |
| GSE63941 | MYO18B | 84700 | 1554579_a_at | 0.4235 | 0.0872 | |
| GSE77861 | MYO18B | 84700 | 1554579_a_at | -0.0572 | 0.5418 | |
| GSE97050 | MYO18B | 84700 | A_23_P68846 | -0.2524 | 0.3981 | |
| SRP133303 | MYO18B | 84700 | RNAseq | -0.5276 | 0.4159 | |
| SRP159526 | MYO18B | 84700 | RNAseq | -0.7781 | 0.3999 | |
| SRP219564 | MYO18B | 84700 | RNAseq | -3.7056 | 0.0000 | |
| TCGA | MYO18B | 84700 | RNAseq | -2.0313 | 0.0032 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MYO18B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYO18B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYO18B | 84700 | 4 | 6 | 20 | |
| GSE20123 | MYO18B | 84700 | 4 | 5 | 21 | |
| GSE43470 | MYO18B | 84700 | 3 | 6 | 34 | |
| GSE46452 | MYO18B | 84700 | 31 | 1 | 27 | |
| GSE47630 | MYO18B | 84700 | 8 | 5 | 27 | |
| GSE54993 | MYO18B | 84700 | 3 | 6 | 61 | |
| GSE54994 | MYO18B | 84700 | 11 | 7 | 35 | |
| GSE60625 | MYO18B | 84700 | 5 | 0 | 6 | |
| GSE74703 | MYO18B | 84700 | 3 | 5 | 28 | |
| GSE74704 | MYO18B | 84700 | 1 | 3 | 16 | |
| TCGA | MYO18B | 84700 | 26 | 14 | 56 |
Total number of gains: 99; Total number of losses: 58; Total Number of normals: 331.
Somatic mutations of MYO18B:
Generating mutation plots.
Highly correlated genes for MYO18B:
Showing top 20/116 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYO18B | KCNA7 | 0.795371 | 3 | 0 | 3 |
| MYO18B | PRRG3 | 0.787265 | 3 | 0 | 3 |
| MYO18B | CHRD | 0.784009 | 3 | 0 | 3 |
| MYO18B | FGF17 | 0.756768 | 3 | 0 | 3 |
| MYO18B | FAM171A2 | 0.755728 | 3 | 0 | 3 |
| MYO18B | SEMA5B | 0.750218 | 3 | 0 | 3 |
| MYO18B | PTGDR2 | 0.744223 | 3 | 0 | 3 |
| MYO18B | AMN | 0.738868 | 3 | 0 | 3 |
| MYO18B | ZMYND10 | 0.736017 | 3 | 0 | 3 |
| MYO18B | CCDC42 | 0.734959 | 3 | 0 | 3 |
| MYO18B | ADAMTS7 | 0.730342 | 3 | 0 | 3 |
| MYO18B | NOXA1 | 0.72893 | 3 | 0 | 3 |
| MYO18B | CELF4 | 0.722175 | 3 | 0 | 3 |
| MYO18B | DPEP3 | 0.71977 | 3 | 0 | 3 |
| MYO18B | SLC35F3 | 0.718121 | 3 | 0 | 3 |
| MYO18B | SIGLEC11 | 0.709891 | 3 | 0 | 3 |
| MYO18B | OR4D1 | 0.708111 | 3 | 0 | 3 |
| MYO18B | TULP2 | 0.707645 | 3 | 0 | 3 |
| MYO18B | CTSE | 0.703054 | 3 | 0 | 3 |
| MYO18B | GTF2IRD2B | 0.702433 | 3 | 0 | 3 |
For details and further investigation, click here
