| Full name: DLG associated protein 2 | Alias Symbol: DAP-2 | ||
| Type: protein-coding gene | Cytoband: 8p23.3 | ||
| Entrez ID: 9228 | HGNC ID: HGNC:2906 | Ensembl Gene: ENSG00000198010 | OMIM ID: 605438 |
| Drug and gene relationship at DGIdb | |||
Expression of DLGAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLGAP2 | 9228 | 216916_s_at | -0.0819 | 0.7550 | |
| GSE20347 | DLGAP2 | 9228 | 216916_s_at | -0.0860 | 0.2723 | |
| GSE23400 | DLGAP2 | 9228 | 216916_s_at | -0.1614 | 0.0000 | |
| GSE26886 | DLGAP2 | 9228 | 216916_s_at | -0.1654 | 0.2933 | |
| GSE29001 | DLGAP2 | 9228 | 216916_s_at | -0.1242 | 0.3544 | |
| GSE38129 | DLGAP2 | 9228 | 216916_s_at | -0.2207 | 0.0022 | |
| GSE45670 | DLGAP2 | 9228 | 216916_s_at | -0.1069 | 0.3344 | |
| GSE53622 | DLGAP2 | 9228 | 118383 | -0.2467 | 0.2309 | |
| GSE53624 | DLGAP2 | 9228 | 118383 | -0.2324 | 0.0435 | |
| GSE63941 | DLGAP2 | 9228 | 216916_s_at | 0.1462 | 0.1907 | |
| GSE77861 | DLGAP2 | 9228 | 216916_s_at | -0.1339 | 0.1424 | |
| SRP133303 | DLGAP2 | 9228 | RNAseq | -1.4786 | 0.0089 | |
| TCGA | DLGAP2 | 9228 | RNAseq | -1.8049 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by DLGAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLGAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLGAP2 | 9228 | 5 | 13 | 12 | |
| GSE20123 | DLGAP2 | 9228 | 5 | 13 | 12 | |
| GSE43470 | DLGAP2 | 9228 | 5 | 9 | 29 | |
| GSE46452 | DLGAP2 | 9228 | 12 | 14 | 33 | |
| GSE47630 | DLGAP2 | 9228 | 10 | 8 | 22 | |
| GSE54993 | DLGAP2 | 9228 | 4 | 14 | 52 | |
| GSE54994 | DLGAP2 | 9228 | 10 | 18 | 25 | |
| GSE60625 | DLGAP2 | 9228 | 3 | 0 | 8 | |
| GSE74703 | DLGAP2 | 9228 | 5 | 7 | 24 | |
| GSE74704 | DLGAP2 | 9228 | 4 | 8 | 8 | |
| TCGA | DLGAP2 | 9228 | 14 | 41 | 41 |
Total number of gains: 77; Total number of losses: 145; Total Number of normals: 266.
Somatic mutations of DLGAP2:
Generating mutation plots.
Highly correlated genes for DLGAP2:
Showing top 20/964 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLGAP2 | RAMP3 | 0.713992 | 3 | 0 | 3 |
| DLGAP2 | DRD5 | 0.694111 | 3 | 0 | 3 |
| DLGAP2 | OR6A2 | 0.689981 | 4 | 0 | 4 |
| DLGAP2 | EDA2R | 0.688165 | 5 | 0 | 4 |
| DLGAP2 | CKM | 0.687388 | 3 | 0 | 3 |
| DLGAP2 | HSPB6 | 0.684662 | 4 | 0 | 4 |
| DLGAP2 | SIX6 | 0.68454 | 7 | 0 | 7 |
| DLGAP2 | KLHDC8A | 0.676474 | 4 | 0 | 4 |
| DLGAP2 | FMN2 | 0.675709 | 3 | 0 | 3 |
| DLGAP2 | UBQLN3 | 0.671833 | 5 | 0 | 4 |
| DLGAP2 | SYT6 | 0.669191 | 4 | 0 | 4 |
| DLGAP2 | RPS6KA6 | 0.666112 | 3 | 0 | 3 |
| DLGAP2 | PSG7 | 0.665994 | 4 | 0 | 4 |
| DLGAP2 | CPTP | 0.66378 | 4 | 0 | 4 |
| DLGAP2 | FSTL4 | 0.662348 | 4 | 0 | 4 |
| DLGAP2 | ZNF717 | 0.660603 | 4 | 0 | 4 |
| DLGAP2 | SPIN2A | 0.659927 | 3 | 0 | 3 |
| DLGAP2 | GRM1 | 0.659461 | 3 | 0 | 3 |
| DLGAP2 | CYP4A11 | 0.656846 | 5 | 0 | 5 |
| DLGAP2 | HPCA | 0.653329 | 4 | 0 | 4 |
For details and further investigation, click here
