| Full name: 3-hydroxyanthranilate 3,4-dioxygenase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p21 | ||
| Entrez ID: 23498 | HGNC ID: HGNC:4796 | Ensembl Gene: ENSG00000162882 | OMIM ID: 604521 |
| Drug and gene relationship at DGIdb | |||
Expression of HAAO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HAAO | 23498 | 205657_at | -0.3482 | 0.2653 | |
| GSE20347 | HAAO | 23498 | 205657_at | -0.2316 | 0.0094 | |
| GSE23400 | HAAO | 23498 | 205657_at | -0.3046 | 0.0000 | |
| GSE26886 | HAAO | 23498 | 205657_at | -0.2993 | 0.0163 | |
| GSE29001 | HAAO | 23498 | 205657_at | -0.2811 | 0.0433 | |
| GSE38129 | HAAO | 23498 | 205657_at | -0.3836 | 0.0000 | |
| GSE45670 | HAAO | 23498 | 205657_at | -0.1847 | 0.0377 | |
| GSE53622 | HAAO | 23498 | 120674 | -0.7600 | 0.0000 | |
| GSE53624 | HAAO | 23498 | 120674 | -1.0512 | 0.0000 | |
| GSE63941 | HAAO | 23498 | 205657_at | 0.2487 | 0.1739 | |
| GSE77861 | HAAO | 23498 | 205657_at | -0.2802 | 0.0063 | |
| GSE97050 | HAAO | 23498 | A_23_P28697 | -0.0866 | 0.6622 | |
| SRP064894 | HAAO | 23498 | RNAseq | -0.7343 | 0.0096 | |
| SRP133303 | HAAO | 23498 | RNAseq | -1.3227 | 0.0000 | |
| SRP159526 | HAAO | 23498 | RNAseq | -0.0952 | 0.8550 | |
| SRP193095 | HAAO | 23498 | RNAseq | -0.8118 | 0.0107 | |
| SRP219564 | HAAO | 23498 | RNAseq | 0.0862 | 0.8821 | |
| TCGA | HAAO | 23498 | RNAseq | -0.4910 | 0.0388 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by HAAO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HAAO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HAAO | 23498 | 12 | 1 | 17 | |
| GSE20123 | HAAO | 23498 | 11 | 1 | 18 | |
| GSE43470 | HAAO | 23498 | 3 | 0 | 40 | |
| GSE46452 | HAAO | 23498 | 1 | 4 | 54 | |
| GSE47630 | HAAO | 23498 | 7 | 0 | 33 | |
| GSE54993 | HAAO | 23498 | 0 | 5 | 65 | |
| GSE54994 | HAAO | 23498 | 10 | 0 | 43 | |
| GSE60625 | HAAO | 23498 | 0 | 3 | 8 | |
| GSE74703 | HAAO | 23498 | 3 | 0 | 33 | |
| GSE74704 | HAAO | 23498 | 10 | 1 | 9 | |
| TCGA | HAAO | 23498 | 35 | 2 | 59 |
Total number of gains: 92; Total number of losses: 17; Total Number of normals: 379.
Somatic mutations of HAAO:
Generating mutation plots.
Highly correlated genes for HAAO:
Showing top 20/1312 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HAAO | FAM163B | 0.764013 | 3 | 0 | 3 |
| HAAO | EBP | 0.76277 | 3 | 0 | 3 |
| HAAO | BARHL2 | 0.756608 | 3 | 0 | 3 |
| HAAO | WDR87 | 0.753443 | 3 | 0 | 3 |
| HAAO | OR10G8 | 0.744356 | 3 | 0 | 3 |
| HAAO | BTBD19 | 0.741529 | 4 | 0 | 4 |
| HAAO | TEN1 | 0.736939 | 3 | 0 | 3 |
| HAAO | CPS1-IT1 | 0.726421 | 3 | 0 | 3 |
| HAAO | ANKDD1A | 0.722992 | 3 | 0 | 3 |
| HAAO | MFSD2B | 0.717616 | 3 | 0 | 3 |
| HAAO | PROCA1 | 0.715389 | 4 | 0 | 4 |
| HAAO | MYO1A | 0.712964 | 9 | 0 | 8 |
| HAAO | FAM189A1 | 0.712894 | 3 | 0 | 3 |
| HAAO | KRTAP5-4 | 0.712458 | 3 | 0 | 3 |
| HAAO | THRSP | 0.712249 | 4 | 0 | 4 |
| HAAO | LELP1 | 0.711992 | 4 | 0 | 3 |
| HAAO | DPYSL4 | 0.711959 | 7 | 0 | 6 |
| HAAO | PAX8 | 0.709673 | 8 | 0 | 8 |
| HAAO | COX4I2 | 0.708897 | 3 | 0 | 3 |
| HAAO | KRTAP20-1 | 0.703813 | 3 | 0 | 3 |
For details and further investigation, click here
