| Full name: neurexin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 9379 | HGNC ID: HGNC:8009 | Ensembl Gene: ENSG00000110076 | OMIM ID: 600566 |
| Drug and gene relationship at DGIdb | |||
Expression of NRXN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRXN2 | 9379 | 209983_s_at | -0.1611 | 0.5887 | |
| GSE20347 | NRXN2 | 9379 | 209983_s_at | 0.0850 | 0.2166 | |
| GSE23400 | NRXN2 | 9379 | 209982_s_at | -0.0694 | 0.0437 | |
| GSE26886 | NRXN2 | 9379 | 209982_s_at | 0.9185 | 0.0005 | |
| GSE29001 | NRXN2 | 9379 | 209983_s_at | 0.0524 | 0.7333 | |
| GSE38129 | NRXN2 | 9379 | 209982_s_at | 0.0160 | 0.9572 | |
| GSE45670 | NRXN2 | 9379 | 209982_s_at | -0.3336 | 0.1595 | |
| GSE53622 | NRXN2 | 9379 | 123850 | 0.1272 | 0.6277 | |
| GSE53624 | NRXN2 | 9379 | 123850 | 0.5861 | 0.0015 | |
| GSE63941 | NRXN2 | 9379 | 209982_s_at | 0.2369 | 0.5014 | |
| GSE77861 | NRXN2 | 9379 | 209983_s_at | -0.1897 | 0.1166 | |
| GSE97050 | NRXN2 | 9379 | A_24_P261470 | -0.0377 | 0.9081 | |
| SRP133303 | NRXN2 | 9379 | RNAseq | -0.5033 | 0.2790 | |
| SRP219564 | NRXN2 | 9379 | RNAseq | 0.7746 | 0.4292 | |
| TCGA | NRXN2 | 9379 | RNAseq | 0.0329 | 0.9228 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NRXN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRXN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRXN2 | 9379 | 7 | 6 | 17 | |
| GSE20123 | NRXN2 | 9379 | 7 | 6 | 17 | |
| GSE43470 | NRXN2 | 9379 | 1 | 3 | 39 | |
| GSE46452 | NRXN2 | 9379 | 9 | 4 | 46 | |
| GSE47630 | NRXN2 | 9379 | 5 | 6 | 29 | |
| GSE54993 | NRXN2 | 9379 | 3 | 1 | 66 | |
| GSE54994 | NRXN2 | 9379 | 6 | 5 | 42 | |
| GSE60625 | NRXN2 | 9379 | 0 | 3 | 8 | |
| GSE74703 | NRXN2 | 9379 | 1 | 1 | 34 | |
| GSE74704 | NRXN2 | 9379 | 5 | 4 | 11 | |
| TCGA | NRXN2 | 9379 | 21 | 9 | 66 |
Total number of gains: 65; Total number of losses: 48; Total Number of normals: 375.
Somatic mutations of NRXN2:
Generating mutation plots.
Highly correlated genes for NRXN2:
Showing top 20/260 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRXN2 | HHLA1 | 0.72106 | 3 | 0 | 3 |
| NRXN2 | CERS1 | 0.701722 | 3 | 0 | 3 |
| NRXN2 | OBP2A | 0.700191 | 3 | 0 | 3 |
| NRXN2 | SIGLEC1 | 0.699087 | 3 | 0 | 3 |
| NRXN2 | TOLLIP-AS1 | 0.696165 | 3 | 0 | 3 |
| NRXN2 | ADAMTSL5 | 0.679414 | 3 | 0 | 3 |
| NRXN2 | CD63 | 0.67571 | 3 | 0 | 3 |
| NRXN2 | SYT6 | 0.6743 | 3 | 0 | 3 |
| NRXN2 | PTRHD1 | 0.673802 | 3 | 0 | 3 |
| NRXN2 | NAALADL1 | 0.663073 | 5 | 0 | 4 |
| NRXN2 | COL23A1 | 0.661755 | 3 | 0 | 3 |
| NRXN2 | RBP2 | 0.659232 | 3 | 0 | 3 |
| NRXN2 | KLHL31 | 0.658014 | 3 | 0 | 3 |
| NRXN2 | NOXO1 | 0.657619 | 3 | 0 | 3 |
| NRXN2 | PLA2G2A | 0.655355 | 3 | 0 | 3 |
| NRXN2 | DSEL | 0.65293 | 3 | 0 | 3 |
| NRXN2 | ACO1 | 0.651439 | 3 | 0 | 3 |
| NRXN2 | ADAM11 | 0.649518 | 4 | 0 | 3 |
| NRXN2 | CMA1 | 0.646274 | 4 | 0 | 3 |
| NRXN2 | VGLL2 | 0.645303 | 3 | 0 | 3 |
For details and further investigation, click here
