| Full name: TATA-box binding protein associated factor 11 | Alias Symbol: TAFII28 | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 6882 | HGNC ID: HGNC:11544 | Ensembl Gene: ENSG00000064995 | OMIM ID: 600772 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF11 | 6882 | 209358_at | 0.5039 | 0.3224 | |
| GSE20347 | TAF11 | 6882 | 209358_at | 0.3065 | 0.0105 | |
| GSE23400 | TAF11 | 6882 | 209358_at | 0.3850 | 0.0000 | |
| GSE26886 | TAF11 | 6882 | 209358_at | 0.2940 | 0.2145 | |
| GSE29001 | TAF11 | 6882 | 209358_at | 0.0360 | 0.9117 | |
| GSE38129 | TAF11 | 6882 | 209358_at | 0.4121 | 0.0000 | |
| GSE45670 | TAF11 | 6882 | 209358_at | 0.2242 | 0.0346 | |
| GSE53622 | TAF11 | 6882 | 94813 | 0.1652 | 0.0123 | |
| GSE53624 | TAF11 | 6882 | 94813 | 0.3661 | 0.0000 | |
| GSE63941 | TAF11 | 6882 | 209358_at | -0.0200 | 0.9624 | |
| GSE77861 | TAF11 | 6882 | 209358_at | 0.0591 | 0.7751 | |
| GSE97050 | TAF11 | 6882 | A_23_P59202 | -0.1987 | 0.5492 | |
| SRP007169 | TAF11 | 6882 | RNAseq | -0.3093 | 0.4032 | |
| SRP008496 | TAF11 | 6882 | RNAseq | -0.1899 | 0.3596 | |
| SRP064894 | TAF11 | 6882 | RNAseq | 0.2693 | 0.0542 | |
| SRP133303 | TAF11 | 6882 | RNAseq | 0.0794 | 0.5363 | |
| SRP159526 | TAF11 | 6882 | RNAseq | 0.3392 | 0.1071 | |
| SRP193095 | TAF11 | 6882 | RNAseq | 0.0979 | 0.1237 | |
| SRP219564 | TAF11 | 6882 | RNAseq | 0.1007 | 0.6476 | |
| TCGA | TAF11 | 6882 | RNAseq | 0.0904 | 0.1095 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF11 | 6882 | 5 | 0 | 25 | |
| GSE20123 | TAF11 | 6882 | 5 | 0 | 25 | |
| GSE43470 | TAF11 | 6882 | 5 | 1 | 37 | |
| GSE46452 | TAF11 | 6882 | 2 | 9 | 48 | |
| GSE47630 | TAF11 | 6882 | 8 | 4 | 28 | |
| GSE54993 | TAF11 | 6882 | 3 | 1 | 66 | |
| GSE54994 | TAF11 | 6882 | 11 | 4 | 38 | |
| GSE60625 | TAF11 | 6882 | 1 | 0 | 10 | |
| GSE74703 | TAF11 | 6882 | 5 | 0 | 31 | |
| GSE74704 | TAF11 | 6882 | 2 | 0 | 18 | |
| TCGA | TAF11 | 6882 | 17 | 16 | 63 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of TAF11:
Generating mutation plots.
Highly correlated genes for TAF11:
Showing top 20/654 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF11 | ZNF121 | 0.843862 | 3 | 0 | 3 |
| TAF11 | CCDC15 | 0.825664 | 3 | 0 | 3 |
| TAF11 | ELOF1 | 0.78812 | 3 | 0 | 3 |
| TAF11 | SMCR8 | 0.780757 | 3 | 0 | 3 |
| TAF11 | TYW5 | 0.776578 | 3 | 0 | 3 |
| TAF11 | EIF3C | 0.770067 | 3 | 0 | 3 |
| TAF11 | ZMYND19 | 0.760614 | 3 | 0 | 3 |
| TAF11 | NUDT19 | 0.756453 | 3 | 0 | 3 |
| TAF11 | SARNP | 0.752237 | 3 | 0 | 3 |
| TAF11 | ZNF700 | 0.749522 | 4 | 0 | 4 |
| TAF11 | WWP1 | 0.743234 | 3 | 0 | 3 |
| TAF11 | PET117 | 0.741188 | 3 | 0 | 3 |
| TAF11 | SYNE2 | 0.733587 | 3 | 0 | 3 |
| TAF11 | DYRK2 | 0.733106 | 4 | 0 | 4 |
| TAF11 | GPATCH1 | 0.731487 | 3 | 0 | 3 |
| TAF11 | WHAMM | 0.727054 | 3 | 0 | 3 |
| TAF11 | ZFP30 | 0.724886 | 3 | 0 | 3 |
| TAF11 | ZNF627 | 0.723233 | 3 | 0 | 3 |
| TAF11 | RIMKLB | 0.722643 | 3 | 0 | 3 |
| TAF11 | ANKRD28 | 0.719793 | 3 | 0 | 3 |
For details and further investigation, click here
